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Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

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381–390 of 456 posts

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#381

If he’s right, we’ll know before the end of Trump’s term. How much are people willing to bet that the incidence of autism will remain unchanged and the administration will disavow everything. “Nobody knew autism was so complicated.” — future Trump, probably.

They’re going to mess with the data to make whatever story they tell ‘right’.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#382
post #50

Earlier quoted context omitted.

You shoudln’t even be entertaining this lunacy with any response. Anything coming out of the RFK jr health department is batshit.

He was legitimately put into a position of power by the american political system. And this is an article by the BBC, probably the most respected news source on the planet. Crazy is now the norm, the leading voice. It must be confronted.

Yep, Democratic Party refused to do a real primary so he switched sides

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#383
I wonder if this hating on autism is part of the regime's focus on loyalty. Autistic people tend to make their own plans and are much more independent. I'd never be able to follow orders in an army for example.

Whereas the current administration is all about loyalty over facts. They even make the meteorological employees do a loyalty test now so they'll follow the narrative and not the science.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#384

Earlier quoted context omitted.

A better example might be how some animals (turtles in particular) have their sex defined by their egg temperature

That isn't a genetic change either, though. Those species of turtle either lack the typical sex-determining chromosomes entirely, or have sex-determining chromosomes which can be inactivated during development. The genotype doesn't change as a result of what temperature the egg is incubated at; its expression does. Further reading: https://www.sciencedaily.com/releases/2021/07/210726102148.h...

That's exactly the point. Gene expression can be modified by the environment

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#385

Here's the relevant study from earlier this year: https://hsph.harvard.edu/news/using-acetaminophen-during-pre... It's a meta-analysis that considered a bunch of individual studies, their effect size, and their quality. It claims that Tylenol use has increased alongside a 20-fold increase in autism rates, suggesting causation, and recommends immediate efforts to reduce Tylenol use during pregnancy. One objection that…

Reading the paper, I'm wondering why they didn't do an actual meta-analysis, to estimate average effect size or likelihood of publication bias. As it is, it's more of a systematic review.

The studies in general they include are case control and prospective cohort studies, predicting neurobehavioral outcomes from paracetamol use retrospectively or prospectively.

The most interesting ones to me are siblings control studies where they compare siblings with and without exposure or case status to control for unmeasured confounds like genetic or family environment variables.

In those studies they reviewed there is still a link but it's much weaker, mostly limited to mothers using paracetamol for a month or more, and on measures not necessarily reflecting autism per se.

That pattern to me is equally suggestive of something other than paracetamol being the causal factor. It could be reflective of a dose response relationship, but you also have to wonder about what else might be going on among women who feel compelled to take paracetamol for over a month at least during pregnancy.

Maybe a paper to call for further better research but not exactly a clear causal link.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#386

Earlier quoted context omitted.

His prior legal track record has no relevance to his current work?

No, because, as forgotoldacc points out, Trump is going to just keep doing whatever he wants regardless, and he wasn't appointed based on actual expertise or prior success: he was appointed because he validates the biases of Trump's base.

I’ll have an aspirin thank you. The main problem isn’t going to be solved.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#387

Earlier quoted context omitted.

Taking 1 gram every couple of hours does NOT seem entirely reasonable when the directions on every Tylenol bottle in the world say to take no more than 1g (2x500mg caps) every FOUR HOURS at most and no more than 4g per 24-hour period. Half the bottle is covered in ominous red warnings about liver damage. It’s like saying jumping on subway tracks when there’s no train is entirely reasonable when there are ample warnin…

Some of y’all have never worked a blue collar job in your lives and it shows.

What’s your point here?

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#388

Not specific to tylenol and autism, but I think important: RFK Jr. will be issuing findings using "gold-standard science" and hold up the findings as definitive (as proof, etc.) at the same time that he completely minimizes and bemoans current scientific processes. While we may be able to tell the difference between RFK's BS science and real science, what does this mean for everyone else? Especially because RFK Jr. d…

Nobody should have been trusting science to begin with. Maybe it will help to show science-believers that they should be more cautious.

What's the alternative? What should one trust instead?

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#389
post #164

There is research correlating autism and mothers taking certain medications (painkillers, antidepressants). Since autism is hereditary, there is a significant chance that these mothers are autistic too. Autistic people have a vastly high risk of depression, and often have unusual pain thresholds, requiring more painkillers. I would not be surprised of the correlation was real, but the direction of action was reversed…

According to my friend who is a geneticist, 30% of cases of autism can be found in DNA. Clearly not all cases are.

Well diagnosing autism is incredibly subjective anyway. It’s not like a broken arm.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#390

It is the safest painkiller currently available. Ibuprofen can cause gut bleeding and renal issues if overdosed on. We all know about opiates. Some facts - typical adult dose is 1g. Max suggested cap on the drug label is 3g per day (about 6 pills at usual 500mg dose). You need to take 10g (20 pills) to be at real risk of hepatotoxicity. So 10 times the typical dose is when you have overdose effects. (basically 20 pil…

> We all know about opiates No, I do not think we do, because it causes none of the side-effects associated with NSAIDs, and it is even safer than acetaminophen, i.e. there is no risk of hepatotoxicity whatsoever. The only side-effect is euphoria. Please do not mention respiratory depression here, that is a non-issue, it matters as so much as liver failure matters with acetaminophen overdoses. Opiates are safer than…

If the safest drug is also the one most prone to misuse, and misuse makes it unsafe, then it is no longer the safest drug. The reason society should be wary is precisely because people misuse it on a scale that vastly eclipses garden variety drugs like acetaminophen.
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