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Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

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Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#221

Post by ricardobeat »

mschuster91 wrote: post #197
devwastaken wrote: post #183

Earlier quoted context omitted.

[flagged]

> there is no evidence of gene expression for autism. The fact that we haven't identified candidate genes for autism and a bunch of other mental health issues doesn't mean these aren't hereditary or have hereditary triggers that make outbreaks easier. > if anything it is epigenetic caused by environmental pollutants and hormone exposure Doubtful. The difference to older times is, we now properly diagnose mental healt…

You don't have to identify the root cause for that though, all it takes is studying the prevalence of a disease across family trees, that would be evidence of genetic expression.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#222

Post by johnisgood »

slenk wrote: post #215
johnisgood wrote: post #167

Earlier quoted context omitted.

> We all know about opiates No, I do not think we do, because it causes none of the side-effects associated with NSAIDs, and it is even safer than acetaminophen, i.e. there is no risk of hepatotoxicity whatsoever. The only side-effect is euphoria. Please do not mention respiratory depression here, that is a non-issue, it matters as so much as liver failure matters with acetaminophen overdoses. Opiates are safer than…

Tylenol isn't addictive. Every opiate is. Even as an alcoholic having to get surgery terrifies me because of how addictive opiates is and that is all doctors push now-a-days. eta this is nothing to do with purity of the product. I never heard of someone selling themselves for Tylenol/acetaminophen

That is an oversimplification, and there are many studies out there proving that people receiving opiates at the hospital do not get psychologically addicted to it, if you are talking about that.

And surely I am not alone with not experiencing euphoria from opiates. It is probably a low % of people though, I do not deny that.

> purity of the product

Overdoses and negative public perception does have to do with that though.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#223

Post by tialaramex »

daveoc64 wrote: post #80

I'm always surprised at the hostility to Acetaminophen on HN (or Paracetamol as we call it here in the UK). It's one of the most commonly used medicines in the UK - and certainly the most popular painkiller. YouGov even did a survey confirming that - https://ygo-assets-websites-editorial-emea.yougov.net/docume... The safety aspects of it are not something that gets raised in the UK much - other than suicide attempts,…

If Paracetamol was invented today it would likely never receive an OTC (over the counter sale, meaning you can just buy it from a retail outlet the way you'd buy cough medicine or toothpaste) license in the UK. Yes, it's safe (and for a bunch of people including me, effective) at the licensed dose, but it's useless at about half that dose, and it's toxic, leading to very nasty deaths in some cases, at just about 3-4 times that effective dose.

That's a very narrow efficacy window. There are modern drugs with a narrow efficacy window but they have pharmacy only licenses or require prescription, which both mean somebody who knows what the hell they're doing sold you the drug, not the automated checkout at a supermarket. That's a vital opportunity to spot that e.g. you're taking this every single day (so it's ongoing pain, probably needs a different intervention, paracetamol is contrandicated) or you have an obvious wound, which needs medical attention not painkillers. Or sometimes very dumb things, like, hey, the actual symptoms you have described mean you're likely pregnant did you even realise that? Would you like a pregnancy test instead ?

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#224

Post by delfinom »

WalterBright wrote: post #218
daveoc64 wrote: post #80

I'm always surprised at the hostility to Acetaminophen on HN (or Paracetamol as we call it here in the UK). It's one of the most commonly used medicines in the UK - and certainly the most popular painkiller. YouGov even did a survey confirming that - https://ygo-assets-websites-editorial-emea.yougov.net/docume... The safety aspects of it are not something that gets raised in the UK much - other than suicide attempts,…

A friend of mine, Eric Engstrom, died of liver failure after taking (too much) Tylenol. Tylenol use over time can sneak up on you in the form of cumulative liver damage. No, I'm not a doctor and this isn't medical advice. Personally, a works-most-of-the-time treatment for headaches is going out for a walk. I don't know why it works, but it does.

Headaches have various causes, and you have to look at where the pain is "originating" from to even try and figure out why. Going out of a walk could be due to a sinus getting irritated and going out for fresh air helps relax it. It can also just be a stress headache and going for a walk relaxes you.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#225

Post by paulvnickerson »

Here's the relevant study from earlier this year: https://hsph.harvard.edu/news/using-acetaminophen-during-pre...

It's a meta-analysis that considered a bunch of individual studies, their effect size, and their quality. It claims that Tylenol use has increased alongside a 20-fold increase in autism rates, suggesting causation, and recommends immediate efforts to reduce Tylenol use during pregnancy.

One objection that I've seen is that the lead author, Dr. Baccarelli, has a conflict of interest because he was an expert witness in a lawsuit about acetaminophen and neurodevelopmental disorders. If you think about it though, someone knowledgeable enough to write this paper is exactly the kind of person you'd want to serve as an expert witness.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#226

Post by yencabulator »

op00to wrote: post #177
throw0101c wrote: post #103

Earlier quoted context omitted.

> There’s a marked increase in mental illnesses diagnosed. There was a marked increase in left-handedness once the 'stigma' of it was removed.

This sinister finding must be further investigated.

And righted?

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#227

Post by delfinom »

protonbob wrote: post #85

There really are risks. It's just not worth it during pregnancy. The pain killing effects of tylenol aren't worth the potential risks during pregnancy. https://www.mountsinai.org/about/newsroom/2025/mount-sinai-s...

>While the study does not show that acetaminophen directly causes neurodevelopmental disorders,

_magic statement_.

Because tylenol is often used to treat a symptom like inflammation, that is where the problem could really lie and needs more studying. Inflammation in the human body causes tons of damage.

Shit, you know why measles is serious in adults? Sure pretty every adult can shrug it off, BUT. It causes mass inflammation in the human body, and because of that, it can and does make men sterile because inflammation kills the testes ability to produce sperm.

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#229

Post by triyambakam »

FirmwareBurner wrote: post #98
docstryder wrote: post #75

It is the safest painkiller currently available. Ibuprofen can cause gut bleeding and renal issues if overdosed on. We all know about opiates. Some facts - typical adult dose is 1g. Max suggested cap on the drug label is 3g per day (about 6 pills at usual 500mg dose). You need to take 10g (20 pills) to be at real risk of hepatotoxicity. So 10 times the typical dose is when you have overdose effects. (basically 20 pil…

I'm sorry but as a non American I can only think about Rehab Officer Tylenol Jones from the Idiocracy movie since that's the first time I heard about Tylenol without knowing it's a drug, and in the movie everyone had well known American brands as their names due to overreach of corporate marketing into society, but that part of the satire went over my head as a European kid back then, thinking Tylenol was just a pers…

There's a Rammstein song, „we all live in Amerika, Coca-Cola, wunderbar!”

Re: Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy

#230

Post by abeyer »

jimbob45 wrote: post #204
loloquwowndueo wrote: post #82

Earlier quoted context omitted.

Taking 1 gram every couple of hours does NOT seem entirely reasonable when the directions on every Tylenol bottle in the world say to take no more than 1g (2x500mg caps) every FOUR HOURS at most and no more than 4g per 24-hour period. Half the bottle is covered in ominous red warnings about liver damage. It’s like saying jumping on subway tracks when there’s no train is entirely reasonable when there are ample warnin…

Some of y’all have never worked a blue collar job in your lives and it shows.

Most of the blue collar coworkers I've had knew full well that you just needed to add some hydrocodone into the mix and you'd be fine w/ a few hundred mg on the acetaminophen for a full shift.
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