How long til we're all on Ozempic? • Hacker News Board

Re: How long til we're all on Ozempic?

#811

Post by addicted » Sat, Oct 12, 2024, 5:58 AM UTC

alluro2 wrote: post #765

arijo wrote: post #573

Earlier quoted context omitted.

Cut on carbs and you will have all the benefits without the nasty side effects. Check https://metabolicmind.org for details. My own experience with the keto diet - https://www.feelingbuggy.com/p/finding-hope-after-decades-of...

I've got to say, pretty frustrating seeing answers like this. It just completely ignores all the real, valid difficulty that people have in fighting obesity. If you "just" follow this diet, that requires discipline, strong will, buying correct supplies, 2h of cooking a day, measuring, counting, adhering to strict eating timeline, for months (years for some people), you'll be golden! There is plenty of research into b…

And there’s no truth to it either.

Cutting carbs only helps to the extent you’ve reduced calorie intake.

People drop their calories too low, and then they take a cheat week after a year or so where they eat pasta, and suddenly they feel a lot better and they’re back to eating more calories and back to gaining weight, leading to yo-yo dieting, which may even be worse than just having a higher than healthy but static weight.

Re: How long til we're all on Ozempic?

#812

Post by addicted » Sat, Oct 12, 2024, 6:00 AM UTC

Izkata wrote: post #753

Etheryte wrote: post #681

Earlier quoted context omitted.

This is about as useful as telling someone who's obese to just eat less. Factually yes, it might help them, but practically they're clearly unable to implement it, probably for a plethora of underlying reasons.

For Millennials in the US, it might be very useful. We grew up with this food pyramid being pushed at us all the time: https://en.wikipedia.org/wiki/Food_pyramid_%28nutrition%29?u... That's a lot of carbs. Only like 3 years ago did I learn they changed it around 20 years ago to be less carb-centric.

No one in the US follows the food pyramid.

Go see what people are eating in real life. There are a lot of studies.

Americans eat way more meat, almost no fruits and vegetables, and a lot of carbs.

The point is that the food pyramid has absolutely no impact and pointing to it and making correlations with it is like doing astrology to explain why you broke your hand while playing basketball the other day.

Edit: you do a great job to illustrate how little anyone knows about these food guidelines.

It took you 17 years to even learn they’ve changed.

Re: How long til we're all on Ozempic?

#813

Post by cashsterling » Sat, Oct 12, 2024, 6:07 AM UTC

timeinput wrote: post #625

unclad5968 wrote: post #585

Earlier quoted context omitted.

In what ways is fitness not within reach for a large portion of the population?

Something like 15% of the world lives in extreme poverty. This is darn near the best it's been in the history of the world (there used to be much more poverty by percentage), but this group would likely have trouble being fit. They might be skinny, but surely not fit. Ignoring that extreme the questions maybe different: How many hours does a median person have free from work, commute, and sleep? How much time must be…

The work-life balance & climate in some areas of the US (and other areas of the world) does make it hard to exercise... but that's only part of the story.

Eating healthier requires very little extra time: perhaps 2-3 hours a week for shopping and meal prep.

- making a salad take 5 minutes.

- baking 10 meals worth of chicken takes 30-45 minutes, with about 5-10 minutes of actual prep time.

- baking a few meals worth of salmon, or some other fish is about the same as chicken.

- cutting up an apple takes 1-2 minutes. Bananas, peaches are ready to go, almost no prep required.

- steaming fresh broccoli takes 3-5 min of prep... and about 15-20 minutes total.

- Equally important is making small decisions to avoid or limit less healthy foods, which requires no time at all and often saves us money [that we can spend on healthier foods instead].

Exercising: 30-60 minutes a day, most days, is ideal but anything is better than nothing. A morning and evening 20 minute walk is great place to start (and can be so relaxing). If a person spends time on Hacker News, they could instead allocate that time to exercise. There are free 15 minutes yoga videos on Youtube. A set of push ups requires 60 seconds. Sometimes I do body weight squats at my desk at work (especially during Teams calls, camera off of course).

Sleep: get at least 7 hours of sleep a night... ideally starting to bed before 11pm. more sleep gives us more energy to put towards being awesome during the day and more energy for exercise and doing the extra work to eat better.

I think almost everyone can set aside 6-10 hours in their week towards building their health. It is a matter of priorities... a person's health should be one of their top priorities.

Re: How long til we're all on Ozempic?

#814

Post by edanm » Sat, Oct 12, 2024, 6:10 AM UTC

unlikelytomato wrote: post #746

mrshadowgoose wrote: post #544

Earlier quoted context omitted.

> Why do we find it acceptable to help people who struggle with alcohol abuse, or nicotine addiction, or opioid addiction, but not to help people who struggle with food abuse? "Getting fit and staying fit" is a form of social capital, because it's extremely hard and only within reach of a small portion of the population. "Being fit" is strongly aligned with "being attractive" which confers all sorts of cross-cutting…

I would say my concerns are far more in the range of downstream effects from the medication. Specifically, I am concerned with muscle retention. Concerns aside, it's a little hard of an argument to swallow having visited many other countries where these things are simply not an issue. How can it be argued that the cause is anything other than behavior when so many others are doing just fine? There is more to this sto…

> Concerns aside, it's a little hard of an argument to swallow having visited many other countries where these things are simply not an issue.

Which countries? As far as I know, most Western countries have roughly similar issues with obesity, at least directionally.

Re: How long til we're all on Ozempic?

#815

Post by arijo » Sat, Oct 12, 2024, 6:15 AM UTC

addicted wrote: post #811

alluro2 wrote: post #765

Earlier quoted context omitted.

I've got to say, pretty frustrating seeing answers like this. It just completely ignores all the real, valid difficulty that people have in fighting obesity. If you "just" follow this diet, that requires discipline, strong will, buying correct supplies, 2h of cooking a day, measuring, counting, adhering to strict eating timeline, for months (years for some people), you'll be golden! There is plenty of research into b…

And there’s no truth to it either. Cutting carbs only helps to the extent you’ve reduced calorie intake. People drop their calories too low, and then they take a cheat week after a year or so where they eat pasta, and suddenly they feel a lot better and they’re back to eating more calories and back to gaining weight, leading to yo-yo dieting, which may even be worse than just having a higher than healthy but static w…

That’s not true - the ketogenic diet is not a calorie restriction diet. It was invented early last century by a medical doctor to simulate fasting and treat epilepsy in children. Low calorie diet lead to yo-yo dieting which is not the case for keto were you are allowed to eat enough calories to be satiated. The binge eating comes for the oscillating glucose and insulin levels driven by the consumption of refined carbs. Carb addiction is the problem and that’s the root cause we should be addressing to stop the metabolic health epidemic that has only been getting worse despite all the pharma profits.

Re: How long til we're all on Ozempic?

#816

Post by I_AM_A_SMURF » Sat, Oct 12, 2024, 6:30 AM UTC

AtlasBarfed wrote: post #232

arcticbull wrote: post #105

Earlier quoted context omitted.

> "Just eat less and exercise more" is trite. If it were that easy, we'd all be in fantastic shape. Studies show it just doesn't work. There was a massive (18,000,000 people) cohort analysis published in 2023 that showed the likelihood of someone losing 5% of their body weight in any given year was 1 in 11 and the likelihood of going from severely obese to normal weight is 1 in 1667. https://www.ncbi.nlm.nih.gov/pmc/…

People need to understand what activity / exercise really is. The desperation of the medical establishment to get people to do ANY exercise meant the general advice is watered down. It's the doom of the statistical distribution. Good outcomes are defined in relative terms on the bell curve, not on absolute performance which exercise is actually suited for. In days of manual labor jobs and lots of walking, people like…

I used to do a hard hike every week which burned around 1000 calories. You're not doing anything else that day unless you keep this up for a very long time.

But yes, great way to lose weight I agree, just not practical for a lot of people.

Re: How long til we're all on Ozempic?

#817

Post by coffeebeqn » Sat, Oct 12, 2024, 6:39 AM UTC

cthalupa wrote: post #719

pedalpete wrote: post #714

Earlier quoted context omitted.

Have you been recommended an exercise regimen, or taken one up yourself? The one the great things about GLP-1s is that with the weight loss, it's easier to be more active once you've lost some of the weight. The negatives is that the current breed promote a loss in muscle mass as well as fat loss, so it is very important to do your best to maintain if not increase muscle while on them. The next generation of drugs ar…

Cagrilintide (paired with semaglutide) and retatrutide are the next wave, though I'm not aware of any research for either indicating an increase in muscle mass. My understanding of the literature is that there's nothing special about semaglutide or tirzepatide that promote muscle loss - it's just people who lose weight based purely on diet tend to also lose muscle mass. Even bodybuilders lose some muscle mass when cu…

Bodybuilders lose muscle and they do a lot of hypertrophy training and high protein eating to counteract it. Probably the average ozempic taker does neither of those so they end up losing more

Re: How long til we're all on Ozempic?

#818

Post by coffeebeqn » Sat, Oct 12, 2024, 6:42 AM UTC

beezlebroxxxxxx wrote: post #411

r00fus wrote: post #386

Earlier quoted context omitted.

Most weight management programs recommend you wean off - and also recommend other drugs if needed (metformin) to for maintenance. The method of these programs is to use the GLP-1 medications to allow you to change your habits significantly while also reducing your weight. The goal being, you keep the new habits and your reduced metabolic requirements which allows you to keep the lower weight.

Interesting. If we think of effectiveness as maintained weight loss and eventually no longer requiring the drug then the next few years and decades will be fascinating to see how effective they are long-term.

Even if you start gaining weight after a year or two I guess you could cycle back on it right ?

Re: How long til we're all on Ozempic?

#819

Post by aucisson_masque » Sat, Oct 12, 2024, 6:49 AM UTC

leoh wrote: post #692

aucisson_masque wrote: post #655

So basically eat shit and then take drugs to lose the weight you accumulated because of your bad diet ?? Am I the only one to realize how this is so wrong? You would think When a pipe leaks, you fix it. You're not going to put a basin under it, empty it every day, pay for a new basin every few week and continue to have your damn pipe leak. Oh man... If only you could teach people how to eat better instead.

You are wrong because being overweight means that your endocrine system is very messed up and can make it extremely difficult to make meaningful changes to your diet and habits. Take a look at the preponderance of folks who have taken GLP-1s here and have affected tremendously positive changes to their diet and exercise habits.

Being overweight doesn't prevent you from putting less junk food in your mouth, and instead eating vegetable.

Re: How long til we're all on Ozempic?

#820

Post by OfficeChad » Sat, Oct 12, 2024, 6:59 AM UTC

indiebat wrote: post #17

I don’t want this to come out insensitive or from under the rock, but why is taking a drug a novel & cool idea (all of a sudden/recently) as opposed to good old fashioned working out and not eating more than what you need? okay, this drug is all kinds of great and it’s the next best thing since green grapes, still not eating more and workout is better than taking drugs that effect your brain right? Are doctors requir…

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