Progress of anti-aging therapies by clinical trial stage

Post by zhoujianfu » Fri, Jan 17, 2020, 6:18 AM UTC

peanutz454 wrote: post #120

sien wrote: post #67

There is a real possibility that in the next few decades some of these therapies might work. The book Lifespan by Dr David Sinclair is really interesting. Sinclair is a professor at Harvard. He's highly optimistic that something will come of the various ideas looking at slowing aging. https://www.amazon.com/Lifespan-Why-Age_and-Dont-Have/dp/150...

So when it happens, will we stop having kids? Because our current population and lifestyle do not seem sustainable. I only see population increasing and lifestyle being more burdensome on environment.

Post by tomerico » Fri, Jan 17, 2020, 7:01 AM UTC

peanutz454 wrote: post #120

sien wrote: post #67

There is a real possibility that in the next few decades some of these therapies might work. The book Lifespan by Dr David Sinclair is really interesting. Sinclair is a professor at Harvard. He's highly optimistic that something will come of the various ideas looking at slowing aging. https://www.amazon.com/Lifespan-Why-Age_and-Dont-Have/dp/150...

So when it happens, will we stop having kids? Because our current population and lifestyle do not seem sustainable. I only see population increasing and lifestyle being more burdensome on environment.

Post by ozfive » Fri, Jan 17, 2020, 7:09 AM UTC

sszz wrote: post #117

Alex3917 wrote: post #115

Earlier quoted context omitted.

More like: Phase I: Will this treatment immediately kill people? Phase II: Does this methodology seem like the right methodology to show some sort of result in larger trials? Phase III: Does the treatment work better than some type of placebo for at least a few weeks without causing obvious and unjustifiable harms during those few weeks. Phase IV: Let's shift our marketing budget into R&D so that we can claim to be u…

This is a super pessimistic and misleading description of phase 2 & 3 trials; actual efficacious drugs do come out of the FDA review process. Many phase 3 trials are against standard of care rather than placebo and many are longer than a few weeks, particularly for treatments where efficacy is hard to prove.

Post by ozfive » Fri, Jan 17, 2020, 7:22 AM UTC

LinuxBender wrote: post #17

chrisco255 wrote: post #10

Earlier quoted context omitted.

Not all of these are new drugs. NMN, for example, is a supplement that you can buy now. It's a bit expensive but the price is dropping as it becomes more popular. Others mentioned include HGH, which has been around for decades. Only problem there is that it's a controlled substance so getting a prescription for anti-aging purposes may be difficult.

I am not saying there isn't a use case for HGH, but you can increase your own natural HGH production through intermittent fasting, l-glutamine, and cycling up/down a few other molecules. I learned this by mistake, from trying to repair damage to my gut. The weird side effect was quite a bit of muscle development and I don't even work out. On top of that, I dampen mtorc1 with Berberine, Sulforaphane, Myrosinase, Trans…

Post by GolDDranks » Fri, Jan 17, 2020, 7:27 AM UTC

lcnmrn wrote: post #87

ganeshkrishnan wrote: post #84

Earlier quoted context omitted.

Ai is hardly hyper inflated. Everything from your phone to cars to planes use ai and machine learning one way or the other.

But it's not actually AI, it's just programmable probability.