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Prenatal cannabis exposure associated with mental disorders in children

nih.gov

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Re: Prenatal cannabis exposure associated with mental disorders in children

#121

Post by sigstoat »

ok_dad wrote: post #58
irrational wrote: post #50

Earlier quoted context omitted.

It’s still a DUI if you drive on it. The week after it was legalized in my state, a person managed to put their car through the second story of a home. The toxicology report showed the only thing in their system was cannabis.

Cannibis can be in your system for weeks or months, so take the authority reports that the accident was caused by cannabis intoxication with a grain of salt, and assume that absent other evidence it might be that the user in this case wasn’t high at the time. I’m not saying this to say no accidents has been caused by cannibis, but that there’s currently no way to tell current level of cannabis intoxication. Authoriti…

this is probably the second-most studied thing in forensic toxicology after alcohol use.

> Cannibis can be in your system for weeks or months

and the levels of active compounds[1] in somebody recently using, vs someone months away from use look very different, and their nature will generally work to the benefit of the defendant when reviewed by a competent forensic toxicologist.

[1] - not a yes/no from shitty screening methods; that kind of information comes off of quarter-million dollar mass spectrometers. they should be able to separate all of the inactive and active compounds from each other, enumerate them and list their exact concentrations in the blood.

Re: Prenatal cannabis exposure associated with mental disorders in children

#122

Post by Maursault »

someguydave wrote: post #78
Maursault wrote: post #26

Earlier quoted context omitted.

Quoted post unavailable.

Women are not in a vacuum, their decisions impact all the people and babies around them and those people and babies have a right to an opinion.

No post body was provided.

Re: Prenatal cannabis exposure associated with mental disorders in children

#123

Post by skissane »

scythe wrote: post #41
darth_avocado wrote: post #12

I’m glad this research is being done. I don’t use cannabis, but I also don’t frown upon it. However some of the conversations on the use of cannabis recently have changed from “it’s a drug, but it isn’t that bad” to “it is completely harmless”. Which in my opinion is very dangerous and could harm entire populations before we have enough research. In my opinion, it should be considered similar category as alcohol, cig…

The primary positive effect of cannabis in the general population is probably that it tends to interfere with alcohol consumption, due to excessive sedation. This probably explains the lack of negative population-level effects of cannabis legalization. The most concerning effect of cannabis is its tendency to increase heart rate. Quite a bit of research is available on the effects of cannabis use — the problem is tha…

Stumbling upon cases like this one really shocked me - “Penile self-amputation due to cannabis-induced psychosis: a case report”

https://jmedicalcasereports.biomedcentral.com/articles/10.11... (Edit: graphic images warning)

If you search PubMed, you will find case reports of other similar incidents. Now, no denying this is an extremely rare adverse effect, but still a quite frightening one. (Also worth stating, many of these reported cases of cannabis-induced psychotic penile self-amputation involve no known history of gender dysphoria.)

Re: Prenatal cannabis exposure associated with mental disorders in children

#124

Post by ch4s3 »

nico wrote: post #94
scythe wrote: post #41

Earlier quoted context omitted.

The primary positive effect of cannabis in the general population is probably that it tends to interfere with alcohol consumption, due to excessive sedation. This probably explains the lack of negative population-level effects of cannabis legalization. The most concerning effect of cannabis is its tendency to increase heart rate. Quite a bit of research is available on the effects of cannabis use — the problem is tha…

Recently attended a lecture on Cannabis by a renowned researcher on the subject (the Director of the UCLA Center for Cannabis & Cannabinoids) The most adverse (proven) effects of Cannabis are: * Frequent bronchitis (for people that smoke it) * Risk of vehicle crashes * Low pregnancy weight, preterm birth, NICU * Mental health (associated risk of schizophrenia, depression, anxiety, suicidal ideation, Cannabis use diso…

> Frequent bronchitis (for people that smoke it)

Yep breathing combustion products is pretty bad for you.

> Risk of vehicle crashes

I'm not aware of any proponents of driving while high.

> Low pregnancy weight, preterm birth, NICU

Again, who's advocating for pregnant women to consume cannabis?

> Mental health (associated risk of schizophrenia, depression, anxiety, suicidal ideation, Cannabis use disorder)

I think this is only for those already genetically predisposed to developing schizophrenia.

> Impaired learning, memory, attention

I'm not sure anyone thinks you should smoke a bunch of drugs before studying for finals.

Just for an ounce of perspective here.

Re: Prenatal cannabis exposure associated with mental disorders in children

#125

Post by subpixel »

moomoo11 wrote: post #101

Is this really surprising? Any time I had used cannabis I felt like my IQ dropped 20-30 points and I would lose hours of my day where it was difficult for me to learn. It made doing household chores not terrible, but brought out a lot of panic inducing moments and erratic behavior. I was thinking about a 100k other things while doing one thing. Later on I realized I wasn't even doing that one thing so well. Anything…

Sounds like you and I have similar reactions to marijuana. From “that smells great” to “I’m talking, but I can’t remember what I was going to say” in just three tokes.

What I’ve come to understand though is that for many other people, marijuana makes them feel great - sharp, alert, at ease and in control. I can empathize with the idea that “this can’t be bad!” even while acknowledging you’d have to be very deluded to smoke anything or consume any psychoactive drug while pregnant just because definitive proof of harm is lacking.

Re: Prenatal cannabis exposure associated with mental disorders in children

#126

Post by tyree731 »

ttpphd wrote: post #74
dr_dshiv wrote: post #17

“ 6 exposures (unplanned pregnancy; maternal alcohol, marijuana, and tobacco use early in pregnancy; pregnancy complications; and birth complications) independently associated with significant but small increases in CBCL total score. Among these 6, none increased the odds of crossing the threshold for clinically significant symptoms by itself. However, odds of exceeding this threshold became significant with 2 exposu…

Huh. Weird that from that result the focus of the conversation is on cannabis.

Well, most of the other factors were pretty agreeable, with marijuana being a somewhat surprising result.

Re: Prenatal cannabis exposure associated with mental disorders in children

#127

Post by Maursault »

asveikau wrote: post #45
Maursault wrote: post #26

Earlier quoted context omitted.

Quoted post unavailable.

https://www.google.com/search?q=cannabis+psychosis People are not making this up. It's a risk that needs to be weighed. Acknowledging this fact is not the same as being in favor of prohibition or criminalization or saying it'll happen to everyone.

I disagree. I think there is a lot of misinformation flooding the nets and the news, and this is provably true. Psychosis is a pretty obvious condition, and it was not difficult to observe psychosis thousands of years ago. Cannabis has been in wide global use since at least 8000BC, and yet... there just historically aren't enough crazy people for this to remotely pass the stiff test.

Re: Prenatal cannabis exposure associated with mental disorders in children

#128

Post by feet »

newswasboring wrote: post #83
feet wrote: post #66

Earlier quoted context omitted.

That's easy. The packages are labeled with nutrient information, don't eat any that contain any amount of trans fats. Also as a side note, hydrogen isn't a noble gas

I think this would mean eating nothing but home cooked meals or a 3x in grocery bill. I'm not even sure of the latter strategy

Really? Most food products I see, even processed ones, don't have trans fats.

What foods do you buy that do?

Re: Prenatal cannabis exposure associated with mental disorders in children

#129

Post by dekhn »

bergenty wrote: post #109
staringback wrote: post #75

Earlier quoted context omitted.

Do you need weed to survive?

We have very specific anadomide receptors in the brain that only respond to weed. Don’t know how much of that is hearsay.

Anandamide receptors. They don't only respond to weed- cannabis happens to be the only plant we know of that produces large amounts of THC or CBD. Anandamide is a chemical our body makes to stimulate those receptors "endogenously" (IE, for its own inner working). The purpose of anandamide receptors is still quite cryptic, or rather, I would say fairly subtle- it seems to "enhance the experience of pleasure in response to reward".

Re: Prenatal cannabis exposure associated with mental disorders in children

#130

Post by tsol »

taurath wrote: post #73
xattt wrote: post #39

Earlier quoted context omitted.

The same sentiment can be applied to current psychedelics research.

Can you post a source for any claim that theyre harmless? I don’t think any reputable researcher has ever said that, but they have started talking about potential for positive effects, which is a far cry from “if you take this it will ruin your life”.

I don't think there are any researchers saying marijuana is anything but beneficial. It's every day people. Same thing for psychedelics. There was a thread on LSD the other day and I had to point out twice that HPPD happens as a result, and is a disorder that can cause significant mental distress. Honestly I think it only does a disservice to the cause to make claims like that
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