Earlier quoted context omitted.
>ghee Cholesterol oxides in Indian ghee: possible cause of unexplained high risk of atherosclerosis in Indian immigrant populations: https://pubmed.ncbi.nlm.nih.gov/2887943/ "Substantial amounts of cholesterol oxides were found in ghee (12.3% of sterols), but not in fresh butter"
> Indian ghee We have been using ghee in India for thousands of years. If immigrant Indians are having problems, they should look into what changed in their diet and lifestyle after they immigrated.
Drastic increase in quantity of ghee (and sugar since a lot of Indian tests are a lot of ghee and sugar) consumed and reduction in labor (trading strenuous, perspiring work for air conditioned, sitting work) could be relevant factors that make ghee consumption from the previous thousand years not comparable to today.