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Had Covid? You’ll probably make antibodies for a lifetime

nature.com

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Re: Had Covid? You’ll probably make antibodies for a lifetime

#351

Post by swader999 »

amluto wrote: post #348
swader999 wrote: post #321

Earlier quoted context omitted.

We still don't have enough data on whether this will suffer ADE. If parent is young, isn't in a highly infectious area and behaves cautiously, they may be making a less risky decision.

We absolutely have enough data to rule out meaningful ADE. Study after study (the phase 3 trials and all the ongoing surveillance) indicates a massive reduction in the rate of severe infection among vaccine recipients. Sure, one can quibble about whether maybe some of the very small number of people who got a vaccine more than a couple weeks before a severe COVID case had a form of ADE, but that’s like saying that we…

ADE doesn't really show up until years later with different strains and different virus.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#352

Post by vinay427 »

laurent92 wrote: post #349
santiagobasulto wrote: post #251

Earlier quoted context omitted.

Some time ago i listened to a respected Argentina scientist (that lives and works in France) saying something: “we can’t confirm nor deny anything about COVID, given the poor quality of scientific procedure we follow in testing” He was complaining of lack of scientific rigorousity with testing (at least in France) and he compared it to the “behind the scenes” of a restaurant’s kitchen. For example, he was saying that…

Elon Musk got himself tested 4 times the same day in 2020. 2 positive 2 negative.

That's not surprising or particularly notable for a rapid antigen test, which is why they're not used as a full replacement for a PCR test in most countries.

The BD rapid test he used seems to be one which a paper [1] indicates has a lower positive percent agreement than a PCR test.

Rapid tests in general, compared directly to PCR, seem to do even worse with one paper [2] finding a symptomatic sensitivity of 72% and an asymptomatic sensitivity of 58%.

[1]: https://pubmed.ncbi.nlm.nih.gov/33023911/

[2]: https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD...

Re: Had Covid? You’ll probably make antibodies for a lifetime

#353

Post by aledalgrande »

XorNot wrote: post #3
mactavish88 wrote: post #2

Does anybody have any ideas as to what this means for people who've had COVID and then get vaccinated with one of the mRNA vaccines? If not, is anyone studying this?

Probably that the vaccine is somewhat irrelevant: though that's up for grabs since what your body targets vs. what the vaccine targets will be subtly different. I'm more interested that this means that quite likely, COVID-19 will be eradicated: with not many advantageous mutation pathways, and if vaccines are conferring immunity forever, it's pretty much going to be burned out of the population one way or the other.

It won't be. Look at vaccines in the US, the have flattened out at around 50%. Many countries are <30%. And there are animal reservoirs. This is not like polio.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#354

Post by nednar »

insaneirish wrote: post #285
nednar wrote: post #159

Earlier quoted context omitted.

In many locations you have hospitals close by with covid stations. So you could bring the people to the virus.

And that would work how, exactly?

For me, this would be a point where I would fully rely on the experts for deciding how to implement that step and check if the plan is feasible. I don't recommend executing such ideas without syncing with authorities and experts.

That shouldn't stop us from brain storming, though, and allow experts to decide, if it's an interesting idea or stupid.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#355

Post by Guvante »

sdsaga12 wrote: post #293
Guvante wrote: post #269

Earlier quoted context omitted.

Technically the wild and crazy ones were "it was bio engineered" and "let's ignore it and gain herd immunity". The former was being touted as justification for violence against Asians and the latter would involve millions of deaths in most countries. Tens of millions world wide.

Approximately 3.5 million globally have died from covid according to the WHO: https://covid19.who.int/ If you include deaths from related factors, like increased poverty or unrest, I'm sure the numbers go up a bit, but not to tens of millions. I don't state this as an attack, by the way. Covid and its entangled cultural and political issues are enormously emotionally charged, and, one way or another, that tends to sk…

COVID has a death per case rate of 3% give or take. It is estimated that only 1/3 of cases are confirmed. Thus we lose 1% of the people infected.

70% herd immunity without vaccines is 0.7% of your population basically. While I don't think we would lose the 49 million that implies unless we ignored it completely that does make saying we would lose 10s of millions if not for vaccinations not far fetched.

Yes I would put good odds we stay under 10 million in reality. I was only talking about the "natural herd immunity" idea.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#356

Post by tylerhou »

swader999 wrote: post #321
unethical_ban wrote: post #231

Earlier quoted context omitted.

Here you are, trying to say that Covid is less of a threat to yourself and others than the vaccine. Very few reactions have occurred. If you're worried about it, also don't go outside, cross a street, or go swimming in any body of water.

We still don't have enough data on whether this will suffer ADE. If parent is young, isn't in a highly infectious area and behaves cautiously, they may be making a less risky decision.

Covid infection produced antibodies can also cause ADE, so that's not a great argument against immunization.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#357

Post by inciampati »

mrtesthah wrote: post #260
seren wrote: post #86

From my understanding if you had an mRNA vaccine, your body was only exposed to an artificial spike protein, so effectively you have spike specific antibodies. On the other hand, if you had a real infection by the virus, you likely have antibodies for the spike protein and other part of the virus like the shell. So from my layman understanding, the immunity should be more resistant to a mutation of the spike protein.…

>So from my layman understanding, the immunity should be more resistant to a mutation of the spike protein. There have been several studies that suggest vaccination provides stronger immunity to mutations. Here's one titled Vaccine-induced immunity provides more robust heterotypic immunity than natural infection to emerging SARS-CoV-2 variants of concern : https://www.researchsquare.com/article/rs-226857/v1

Did any of these studies compare people who were vaccinated with people who had COVID19 at the same time relative to sampling? In this paper the two groups are separated in time, making it very hard to interpret the results. The effect could simply be due to difference in antibody titer at different times from infection.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#358

Post by nickysielicki »

CorrectHorseBat wrote: post #340
nickysielicki wrote: post #333

Earlier quoted context omitted.

> Confirmed by PCR What was the cycle threshold? The problem with this whole manufactured pandemic is that all the numbers and tests are bullshit because people are doing bad science. The massive relief bills introduced financial incentives to do bad science. It’s institutional failure at a massive scale.

Positive tests, hospitalisations and deaths are highly correlated. How could that be if the test are bullshit?

What do you mean by “highly” correlated? Source?

Do a google for “COVID PCR ct cycle threshold” and you’ll come across loads and loads of good articles about how the meaning of a positive PCR test is relative to the cycle threshold.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#359

Post by ulfw »

kevin_thibedeau wrote: post #279
santiagobasulto wrote: post #251

Earlier quoted context omitted.

Some time ago i listened to a respected Argentina scientist (that lives and works in France) saying something: “we can’t confirm nor deny anything about COVID, given the poor quality of scientific procedure we follow in testing” He was complaining of lack of scientific rigorousity with testing (at least in France) and he compared it to the “behind the scenes” of a restaurant’s kitchen. For example, he was saying that…

This is also why you never want your DNA to end up where it can be used for false accusations against you. Lab work isn't trustworthy against mistakes.

Paranoid a bit much?

Re: Had Covid? You’ll probably make antibodies for a lifetime

#360

Post by sharken »

loveistheanswer wrote: post #189

It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. Similar to how so many people have been unwilling to even consider a lab leak was a possibility, until just now it seems, because that idea was heresy to the orthodox dogma that ordained Scientists are Saviors. Humans have equated sickness…

It certainly seems very hard for a lot of people in countries with high vaccination percentage to cope with Corona being "just another disease" at this point.

My hope is that all the laws and restrictions will be rolled back as we learn that we can live with Corona.

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