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Had Covid? You’ll probably make antibodies for a lifetime

nature.com

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Re: Had Covid? You’ll probably make antibodies for a lifetime

#331

Post by singhrac »

blhack wrote: post #237
nednar wrote: post #48

If recovered people have longer term protection than vaccinated people (which is one possible interpretation of the headline's statement), would it make sense to first vaccinate someone and then expose them to the real virus, thereby generating the benefits with a much much lower risk or maybe even zero risk?

That will probably happen naturally. People tend to alter their behavior a lot after getting vaccinated.

I mean this seems like a great way to create vaccine resistant variants... but it's inevitable I guess.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#332

Post by hef19898 »

Hard_Space wrote: post #49
andy_ppp wrote: post #24

Does anyone know if PCR tests will find out if you've had the virus, after you had the vaccine?

My girlfriend got infected about ten days after my second AstraZeneca jab. We didn't isolate. I got tested: - Zero naturally-occurring antibodies (the kind you would get from having had COVID). - Strong presence of vaccine-induced antibodies. However, given the timing, I am still uncertain as to whether I contracted COVID during that post-second-jab 4 weeks when my girlfriend was infected (I gave blood for the test w…

Even if you were, if you didn't have any symptoms the vaccine did it's job. In which case you were not infectious neither.

I hope you better half fully recovered by now.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#333

Post by nickysielicki »

seren wrote: post #86

From my understanding if you had an mRNA vaccine, your body was only exposed to an artificial spike protein, so effectively you have spike specific antibodies. On the other hand, if you had a real infection by the virus, you likely have antibodies for the spike protein and other part of the virus like the shell. So from my layman understanding, the immunity should be more resistant to a mutation of the spike protein.…

> Confirmed by PCR

What was the cycle threshold? The problem with this whole manufactured pandemic is that all the numbers and tests are bullshit because people are doing bad science. The massive relief bills introduced financial incentives to do bad science. It’s institutional failure at a massive scale.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#334

Post by grey-area »

trompetenaccoun wrote: post #262
seren wrote: post #86

From my understanding if you had an mRNA vaccine, your body was only exposed to an artificial spike protein, so effectively you have spike specific antibodies. On the other hand, if you had a real infection by the virus, you likely have antibodies for the spike protein and other part of the virus like the shell. So from my layman understanding, the immunity should be more resistant to a mutation of the spike protein.…

> It is still possible it was a defective test the second time, and something else than Covid. Now that the whole world has gone banana over a virus outbreak, it's really important to look at and understand how these tests work. Just because she tested positive does not mean she was really sick with covid, nor does it mean that the test was defective if we assume she didn't have it. It's not an on/off thing, it depen…

You can see from the figures released by various governments on testing rates vs cases that the false positive rate on tests is very low (< 1%, probably less than 0.2%). There have also been a few documented cases of catching it twice, so this is very rare but possible. So either cause is possible in this case, and the tests are really quite reliable as tests go.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#335

Post by hef19898 »

mywittyname wrote: post #143
struxure wrote: post #56

Earlier quoted context omitted.

It may happen, also it is worth to notice that the immunity should form after the second vaccine

And it takes a few weeks after that second shot for full immunity to kick in. My vaccine details said two weeks after the second does for maximum immunity, but Moderna might be different.

And even then no vaccine is 100% effective in each and every individual. Without pre-vaccine tests it is also impossible to say whether or not a patient was already infected before getting the shot.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#336

Post by logicchains »

dmlittle wrote: post #275
loveistheanswer wrote: post #189

It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. Similar to how so many people have been unwilling to even consider a lab leak was a possibility, until just now it seems, because that idea was heresy to the orthodox dogma that ordained Scientists are Saviors. Humans have equated sickness…

I’m not sure if all natural immunities are stronger, or even strong. I’m not denying those exists but I also personally know 3 people that have gotten COVID-19 twice. If natural immunity only protects against a particular strain and the vaccine against a group of them I think that’s still a solid reason to continue pushing for people to get vaccinated.

For influenza it's been found that natural immunity provides better protection against future variants than vaccination https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870374/

Re: Had Covid? You’ll probably make antibodies for a lifetime

#337

Post by logicchains »

Scoundreller wrote: post #297
dmlittle wrote: post #275

Earlier quoted context omitted.

I’m not sure if all natural immunities are stronger, or even strong. I’m not denying those exists but I also personally know 3 people that have gotten COVID-19 twice. If natural immunity only protects against a particular strain and the vaccine against a group of them I think that’s still a solid reason to continue pushing for people to get vaccinated.

The vaccines (so far) all use sequences of the spike protein from an early sample of COVID-19. They just make spike proteins and your body sees it and becomes immune to it. They've made some modifications, but for better stability/structure outside of the virus, but not (yet) to address variants. If anything, infection from current circulating virus is more relevantly effective (but obviously more dangerous than the…

>The vaccines (so far) all use sequences of the spike protein from an early sample of COVID-19.

This is not true of Sinovac, which is a "good-old-fashioned" vaccine and provides exposure to the full (dead) virus.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#338

Post by procombo »

jonnycomputer wrote: post #289
xienze wrote: post #261

Earlier quoted context omitted.

> It almost seems like a lot of people don't want the data to indicate that natural immunity is strong and long lasting, even though the data shows that reinfection is extemely rare. I too remember when the concept of "natural immunity to Covid" was a wild, dangerous conspiracy theory, along with the "came out of the Wuhan lab" theory. Funny watching the narrative change in real time.

Natural immunity is great. If you survive. And if you don't give it to others. Almost impossible not to give it to others. Relying on it was pretty reckless, especially given how little we understand it.

> Almost impossible not to give it to others.

Your facts are old, very old.

Transmissibility has been linked to the nasopharyngeal viral load during onset symptoms. [https://pubmed.ncbi.nlm.nih.gov/33296437/] The virus may not be as present in your nasal discharge, or breath. We've also known from the start transmissibility is also definitely not linked to the severity of symptoms.

When you read from articles from the CDC such as [https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-si...] they don't mean all people spread it the same way, just "we have found it spreads commonly in these three ways".

Ironically enough, we traced my positive infection to a non-human animal which sneezed in my face. Within a day I had conjunctivitis (pinkeye). I had non-typical symptoms before severe fatigue set in. I just thought I was going through bad caffeine withdrawal at the time.

Locked inside the house with my spouse and kids for two weeks with symptoms, breathing all over each other, laughing in each others faces, touching the same items, etc.

I only got tested on day 13 when the respiratory and heart symptoms set in. 6 months later I still have some lingering issues. Nobody else in the house or who I associated with ever got it, and they tested every 5 days for a month.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#339

Post by CogitoCogito »

seren wrote: post #86

From my understanding if you had an mRNA vaccine, your body was only exposed to an artificial spike protein, so effectively you have spike specific antibodies. On the other hand, if you had a real infection by the virus, you likely have antibodies for the spike protein and other part of the virus like the shell. So from my layman understanding, the immunity should be more resistant to a mutation of the spike protein.…

> That being said I also know someone who got Covid 2 times, once in march 2020 and once in april 2021. (Confirmed by PCR the 2 times). The second time was much milder, but still she had to stop working for a week (versus one month the first time). It is still possible it was a defective test the second time, and something else than Covid.

For what it's worth my girlfriend is currently recovering from her second bout of covid. She had it first about a year ago and then second about a month and a half ago. Confirmed by PCR test and antibody tests afterwards as well as totally consistent symptoms. The first time knocked her out totally about a week and left her tired for a few weeks while the second time knocked her out totally for maybe 2 1/2 weeks and she's still quite weak now 6 weeks later, so the second case has been much worse.

Obviously just anecdotal, but getting it twice does happen and the second time apparently can be worse.

Re: Had Covid? You’ll probably make antibodies for a lifetime

#340

Post by CorrectHorseBat »

nickysielicki wrote: post #333
seren wrote: post #86

From my understanding if you had an mRNA vaccine, your body was only exposed to an artificial spike protein, so effectively you have spike specific antibodies. On the other hand, if you had a real infection by the virus, you likely have antibodies for the spike protein and other part of the virus like the shell. So from my layman understanding, the immunity should be more resistant to a mutation of the spike protein.…

> Confirmed by PCR What was the cycle threshold? The problem with this whole manufactured pandemic is that all the numbers and tests are bullshit because people are doing bad science. The massive relief bills introduced financial incentives to do bad science. It’s institutional failure at a massive scale.

Positive tests, hospitalisations and deaths are highly correlated. How could that be if the test are bullshit?
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