Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Current RNA vaccines protect against worrying coronavirus variants

nature.com

Post reply on HN
Print view View original

221–230 of 324 posts

Re: Current RNA vaccines protect against worrying coronavirus variants

#221

Post by nickthemagicman »

loxias wrote: post #57
sigmaprimus wrote: post #38

Earlier quoted context omitted.

I agree, unfortunately there have been so many half truths and misleading articles both online and on legacy media that I find myself not knowing what or who to trust anymore. I have an appointment to get my first jab in 43 hours from now and I am bouncing back and forth between getting it and cancelation. Five years ago I would not be having these doubts but it seems like everyone has alterior motives. I wish the so…

> I have an appointment to get my first jab in 43 hours from now and I am bouncing back and forth between getting it and cancellation. Cancellation??!??! WTF? Why? You have a free, safe, live-saving vaccine being offered to you! Why would you not take it?? Putting aside the fact that not being vaccinated is a horrible selfish act that hastens the evolution of a more virulent strain and more death, don't you want to r…

If variants or strains existed that could avoid the immune system surely it would be evading the immunity of the people in Texas, Florida or the over 50% of other states that have had no Covid restrictions for months... infection rates would be skyrocketing instead of lingering at record lows.

Stop fear mongering.

Re: Current RNA vaccines protect against worrying coronavirus variants

#222

Post by nickthemagicman »

sigmaprimus wrote: post #38
vmception wrote: post #33

I literally saw the opposite headline about Pzifer versus a strain in India today The actual article said "modest antibody evading capabilities“ I hate that the internet has become this way

I agree, unfortunately there have been so many half truths and misleading articles both online and on legacy media that I find myself not knowing what or who to trust anymore. I have an appointment to get my first jab in 43 hours from now and I am bouncing back and forth between getting it and cancelation. Five years ago I would not be having these doubts but it seems like everyone has alterior motives. I wish the so…

If you're under 55 and are healthy your chances of dying from this virus are basically non-existent.

You'll get a sniffle/fever for a few days and then be immune.

Don't put an experimental drug into your body for no reason.

Anyone who says variant or strains are a problem has merely to look at over 50% of the United States with no covid restrictions for months who are at record lows of infections and with minimal vaccines.

The variant or strain problem is a nothing burger.

Re: Current RNA vaccines protect against worrying coronavirus variants

#223

Post by nickthemagicman »

bawolff wrote: post #96
sigmaprimus wrote: post #80

Earlier quoted context omitted.

>>>Putting aside the fact that not being vaccinated is a horrible selfish act that hastens the evolution of a more virulent strain and more death. Rhetoric like that is almost as bad as the conspiracies floating around. Brow beating someone with legitimate concerns is not right. Im social distancing, wearing a mask doing all the things necessary and successfully I might add to not aquire or transmit the virus. So ple…

> Im social distancing, wearing a mask doing all the things necessary Those things are emergency measures, that are important, but not anywhere near as effective as vaccines are. They stop things from rapidly spiraling out of control so instead they just slowly spiral. Its a holding action, one with a pretty high cost, not a solution. > that has been rushed through trials They've had the same amount of safety testing…

They're choosing to become immune naturally instead of pumping an experimental drug into his body.

If they're under 55 and healthy they're actually doing a good thing by letting people who actually need the vaccine get it.

It's arguable that actually getting the vaccine if you're healthy and young is selfish by stopping someone who needs it from getting it.

Think if all the people in India and Brazil had the vaccines the young and healthy are taking in America.

Re: Current RNA vaccines protect against worrying coronavirus variants

#224

Post by pontus »

killingtime74 wrote: post #140
georgeplusplus wrote: post #132

Earlier quoted context omitted.

I’m curious, what is your education background in? Do you have some sort of medical education or this is a regurgitation of some sources you’ve read as a hobbyist? I ask this because you seem to talk from a place of authority and fact and i respect that but typically thought of Ycomb as a place comp sci folks usually congregate.

Maybe you should ask for sources instead. Authority is the wrong thing to trust in science

I completely agree... in principle. That being said, I actually think we tend to underestimate the value of trusting experts. Often times the sources out there that one could be quoting espouse conflicting and ambiguous conclusions and it ironically takes an expert to be able to parse through them all. If we could all trust experts a bit more and, rather than ask for sources, instead ask our experts to explain their reasoning to us, I think we'd all be better off in the long run in that we'd actually be learning from them rather than trying to constantly bootstrap becoming experts ourselves.

Re: Current RNA vaccines protect against worrying coronavirus variants

#225

Post by bavent »

nickthemagicman wrote: post #222
sigmaprimus wrote: post #38

Earlier quoted context omitted.

I agree, unfortunately there have been so many half truths and misleading articles both online and on legacy media that I find myself not knowing what or who to trust anymore. I have an appointment to get my first jab in 43 hours from now and I am bouncing back and forth between getting it and cancelation. Five years ago I would not be having these doubts but it seems like everyone has alterior motives. I wish the so…

If you're under 55 and are healthy your chances of dying from this virus are basically non-existent. You'll get a sniffle/fever for a few days and then be immune. Don't put an experimental drug into your body for no reason. Anyone who says variant or strains are a problem has merely to look at over 50% of the United States with no covid restrictions for months who are at record lows of infections and with minimal vac…

Tell that to my 30-year-old sister - who still has migraines and extreme fatigue a year after catching covid, who was healthy, an avid runner, and had no preexisting conditions before.

Re: Current RNA vaccines protect against worrying coronavirus variants

#226

Post by nickthemagicman »

bavent wrote: post #225
nickthemagicman wrote: post #222

Earlier quoted context omitted.

If you're under 55 and are healthy your chances of dying from this virus are basically non-existent. You'll get a sniffle/fever for a few days and then be immune. Don't put an experimental drug into your body for no reason. Anyone who says variant or strains are a problem has merely to look at over 50% of the United States with no covid restrictions for months who are at record lows of infections and with minimal vac…

Tell that to my 30-year-old sister - who still has migraines and extreme fatigue a year after catching covid, who was healthy, an avid runner, and had no preexisting conditions before.

-----

27,000 (ish) people under the age of 55 died of Covid out of 350 million.

0.0007714285% chance of dying from Covid.

------

32% of 10 million(ish) infections reported 'long covid'. This is 3.2 million.

------

2% of America are hypochondriacs. That's 6.4 million people.

-----

Statistically it's most likely that your sister is a hypochondriac and she needs a psychiatrist.

------

Also, this is what it sounds like when people give anecdotal evidence on the internet.

https://youtu.be/xzYO0joolR0

-----

Reference for long Covid statistics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392393/

Re: Current RNA vaccines protect against worrying coronavirus variants

#227

Post by danparsonson »

miked85 wrote: post #159
loxias wrote: post #88

Earlier quoted context omitted.

> we should respect their choices Honestly, why should I do that? I would if their choices only affected themselves. People have a right to control their own destiny. But their choices affect me, and, more importantly, those I care about. So no, I don't respect anyone's "choice" to be an unvaccinated asshole, increasing the chance that people I care about will die. I don't respect the "choice" to aide a foreign micro…

> But their choices affect me If you and your family get vaccinated, how do their choices affect you?

As far as I know, I haven't had COVID, but other people having it has certainly ruined my year and everyone else's regardless. There's a lot more at stake than just your personal health.

Re: Current RNA vaccines protect against worrying coronavirus variants

#228

Post by brigandish »

o-__-o wrote: post #203
brigandish wrote: post #174

Earlier quoted context omitted.

They wrote: > The immune response developed to our vaccines is quite specific - they only generate the spike protein - which leads to a much less diverse response than a natural infection. Which tells me that your response of: > You seem to have no idea what you are reading. Of course vaccines aren't going to have antibodies against the nucleocapsid -- they only generate antibodies against the spike! is wholly inappr…

The N protein is evasive, I do not believe your body can mount an effective (neutralizing antibodies) defense. But I guess you are right, your body can still fight it which is overall better than just fighting off the virus with vaccine protection

I wasn't making any statement about natural immunity versus vaccine provoked immunity, but the attitude and sloppiness of the commenter and comment I replied to. I have no idea if one is "better" than the other.

Re: Current RNA vaccines protect against worrying coronavirus variants

#229

Post by koheripbal »

garmaine wrote: post #79
Clewza313 wrote: post #49

Earlier quoted context omitted.

India is by and large not using Pfizer. Evidence to date points to AstraZeneca (which they are using) being quite effective in preventing serious illness.

So far ALL vaccines are effective against serious illness with all variants.

While this is very likely true, this has not been conclusively studied.

Only certain variants have been studied against certain vaccines.

Re: Current RNA vaccines protect against worrying coronavirus variants

#230

Post by koheripbal »

thomasahle wrote: post #150
vmception wrote: post #33

I literally saw the opposite headline about Pzifer versus a strain in India today The actual article said "modest antibody evading capabilities“ I hate that the internet has become this way

From what I have read, the antibodies are usually the least robust part of the response system. The real immunity comes from the T cells which will create new antibodies when needed, and may adjust those to variations in the strain.

They are they boots on the ground of the immune system. They just don't stick around more than a few months after infection.
Post reply on HN