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Suppressing a gene by using its antibody can lead to tooth growth: animal study

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Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#151

Earlier quoted context omitted.

I have never heard of this Novamin toothpaste before. Nor has any of my dentists ever recommended it. It looks like the popular brand is Sensodyne.

I never heard of Novamin, but I used Sensodyne for years becase it tastes better.

Has it helped with maintaining the health of your teeth?

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#152

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

> In this type of economic environment why would dentists allowed everyone to have perfectly healthy teeth?

This is utter nonsense. As someone close to the dental field, I can tell you that 99% of people already can have perfect teeth if they cut down/eliminate sugar consumption + brush and floss daily. No one does this. Pretty much all dentists want them too.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#153
post #31

Whatever progress it may provide, I am certain that dentists and dentists' associations will slowly and surely entomb any process that reduces the sum of their individual annual incomes. I believe Adam Smith called it "the invisible hand" (w/o explicitly noting that the "invisible boot" is jammed into the "invisible customers"' collective asses).

It's so sad that most dentists optimise for billable revenue, even at the detriment of long term patient health. Fillings for example always degrade and need repairs after X years. Drilling and filling even the smallest cavity puts that teeth on a lifetime progression to bigger and bigger fillings, eventually a root canal, eventually an implant. Cavities, on the other hand can be arrested (stopped), and if small can…

> Cavities, on the other hand can be arrested (stopped), and if small can even be remineralised. Yes, most dentists don't tell you that!

What is with this sentiment about evil dentists wrecking peoples' teeth prevalent in this thread? Any dentist will tell you that if you brush and floss daily and consume sugar responsibly, that your teeth will be healthy and happy for the vast majority of your life. A VERY small percentage of the population actually does this.

There is no big dental conspiracy to destroy our teeth. We do that just fine on our own.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#154

The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.

as long as they are only growing in your mouth, thats still a solution. Now, having teeth grow om your body randomly, thats a horror movie

It's ... it's ... possible to get cancer in the teeth. If it somehow breaks off and gets into other parts of the body. :|

Also don't google teratoma, or "giant neglected ameloblastoma" :(

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#155
post #122

Earlier quoted context omitted.

There's overwhelming evidence against such a broad statement. There are good mechanics, cars are getting safer, cops do fight crime, soldiers do fight wars and so on, social workers so do their jobs, teachers usually teach and so on. You can say the same for every kind of work -- that you are incentivized to do a poor work so that there's more demand for the work, but the counter incentive is the free market. If othe…

> ... but the counter incentive is the free market. Yes. Which is why the free market is ILLEGAL in the medical system, in the police system, in the educational system, in the judiciary system...

Lol, how do you manage to keep your sanity on HN? Everyone else thinks that medicine/police/education/judiciary is so special that the free market cannot deal with it.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#156

Earlier quoted context omitted.

> ... but the counter incentive is the free market. Yes. Which is why the free market is ILLEGAL in the medical system, in the police system, in the educational system, in the judiciary system...

Lol, how do you manage to keep your sanity on HN? Everyone else thinks that medicine/police/education/judiciary is so special that the free market cannot deal with it.

It's difficult :)

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#157

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

Unfortunately, stuff like this is what makes it clear to me that all claims of slowing aging / reversal are a complete joke. We can't even put a hard layer on a tooth that mimics a natural layer, seriously? Not to mention that we can't prevent baldness, nor do we REALLY know how much muscle control can reverse myopia. We can't even re-attach nails to the nail base, etc, etc, etc.

Probably not for us, but as soon as billionaires start dying some of them will get very scare of death, and put all his money in, and in future probably that fountain of youth will be reserved for a very small minority, or it will be like a commercial product for the elite, aristocrats mainly ...

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#158
post #78

Earlier quoted context omitted.

My dentist friend claims he makes far more money per hour from cleanings than from fillings. This is because most of a cleaning is done by a relatively lowly paid hygienist but still requires him popping in for 5 minutes and a filling requires him to be there the whole time.

That's really strange. Here in Norway I visit a dentist roughly once a year and usually only see my dentist if the dental hygienist has found a problem.

5 minutes may be a bit long for the US. I don't know if it's a legal requirement that the dentist pop in (to supervise) or because people will balk at paying as much without a Doctor appearing. I'm not aware of the dentist usually finding things that the hygienist missed.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#159
post #120

Earlier quoted context omitted.

Because any regrowth solution would be quite expensive, time consuming and prone to problems. It would likely be performed by surgeons and monitored by orthodontists there couls be multiple teeth comming out, missaligned and so forth. I'd much rather do things the old fashion way than risk all sorts of problem down the line, have multiple trips, wait months upon months for my teeth to regrow. As a last resort, or ins…

Regeneration need not be expensive. The cells can do the work, as evidenced by the embryo. We just have to figure out how to tell the cells to do it again. And, critically, tell them to stop when they're done...

Something tells me the "botox" cosmetical procedures are expensive where only doctors are allowed to do it.

Surely teeth regrowth must be more expensive and more complicated than that.

A simple anesthesia for tooth cannot be performed by someone who is not a certified dentist.

I'm just speculating that tooth regrowth will be in the same ballpark as implants and it will be just another option.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#160
post #41

Earlier quoted context omitted.

Novamin toothpaste has been life changing for me. Cannot recommend highly enough. A tooth that was deteriorating and the dentist wanted to cap is now fine enough for them to simply keep an eye on.

I just started using toothpaste with nano-Hydroxypatite after a recommendation from a friend. Obviously I can't say much about its effectiveness long-term. But it feels amazing. Feels like there's a protective layer over the enamel - hopefully there actually is! Apparently, nano-Hydroxypatite is even more effective than Novamin (which is still good): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121804/ If you're in…

Another interesting teeth restoring substance I just discovered:

Oligopeptide P11-4 [1]

[1]https://en.wikipedia.org/wiki/Oligopeptide_P11-4

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