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Suppressing a gene by using its antibody can lead to tooth growth: animal study

u-fukui.ac.jp

121–130 of 163 posts

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#122

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

There's overwhelming evidence against such a broad statement.

There are good mechanics, cars are getting safer, cops do fight crime, soldiers do fight wars and so on, social workers so do their jobs, teachers usually teach and so on.

You can say the same for every kind of work -- that you are incentivized to do a poor work so that there's more demand for the work, but the counter incentive is the free market.

If others can do a better job than you and eat your lunch, they will.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#124
post #31

Whatever progress it may provide, I am certain that dentists and dentists' associations will slowly and surely entomb any process that reduces the sum of their individual annual incomes. I believe Adam Smith called it "the invisible hand" (w/o explicitly noting that the "invisible boot" is jammed into the "invisible customers"' collective asses).

It's so sad that most dentists optimise for billable revenue, even at the detriment of long term patient health. Fillings for example always degrade and need repairs after X years. Drilling and filling even the smallest cavity puts that teeth on a lifetime progression to bigger and bigger fillings, eventually a root canal, eventually an implant. Cavities, on the other hand can be arrested (stopped), and if small can…

I've had multiple dentists(including my wife) tell me not to work on certain small cavities, or to use sensodyne.

Some have been under observation for more than 20 years.

I'm also sure they have re-mineralization treatments they do on site, if it was really worth it, they'd be glad to take your money for that.

I'm sure they have exact procedures for when to work on a cavity or not.

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#125

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

Look up "medicare accountable care"

Edit: I did it for you:

"An accountable care organization (ACO) is a healthcare organization that ties provider reimbursements to quality metrics and reductions in the cost of care"

https://en.wikipedia.org/wiki/Accountable_care_organization

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#126

Earlier quoted context omitted.

>Cavities, on the other hand can be arrested (stopped), and if small can even be remineralised. Yes, most dentists don't tell you that! >Careful monitoring and patient education on the other hand can lead to permanently keeping that natural teeth, as our teeth are living and can heal. Do you have any sources for this? I'm not disagreeing; I hope it's true.

I'd be suspicious of those claims – anecdotal but, unless US doctors differ greatly, neither of those are secrets that have been withheld from me by dentists in 3 European countries. In fact the second statement is surely the basis for most modern dentistry...? (I said US there because it's an assumption that the US approach to dentistry may be different to rest of the world. From afar, seems more cosmetic focused wi…

Well it isn't like dentists in the US are real doctors like in other countries

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#127
post #120

Although amazing, I am following similar news for last 20 years, and promise of tooth regrowth was as a holly grail of dental health, but on the other side it is similar like a nuclear fusion always 20 years away. Process goes like this, "big news -> excitement -> and then nothing -> few years later again nothing -> you go to you dentist for regular check and when you ask he laughs in your face." I read about steam c…

Because any regrowth solution would be quite expensive, time consuming and prone to problems. It would likely be performed by surgeons and monitored by orthodontists there couls be multiple teeth comming out, missaligned and so forth. I'd much rather do things the old fashion way than risk all sorts of problem down the line, have multiple trips, wait months upon months for my teeth to regrow. As a last resort, or ins…

That is interesting way of thinking, make sense, although it would be nice to have options, and then you choose on your own. Like you will go to dentist and they tell you:

- option 1 costs $$ and you need to wait 5 months and there is 2% danger of genetic mutation

- option 2 costs $ it is immediate but over time you need to come again and it will cost you $$ over 10 years, it does not look as nice and maybe there are side effects

- options 3 cost .c but has mercury that can over 30 years cause serious issue ...

Something along those lines

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#128
post #122

Earlier quoted context omitted.

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

There's overwhelming evidence against such a broad statement. There are good mechanics, cars are getting safer, cops do fight crime, soldiers do fight wars and so on, social workers so do their jobs, teachers usually teach and so on. You can say the same for every kind of work -- that you are incentivized to do a poor work so that there's more demand for the work, but the counter incentive is the free market. If othe…

> ... but the counter incentive is the free market.

Yes. Which is why the free market is ILLEGAL in the medical system, in the police system, in the educational system, in the judiciary system...

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#129

Earlier quoted context omitted.

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

It's worse than saying we should only pay devs the days there's no bugs in production, doctors can't decide to magically prevent diseases from existing or accidents to happen.

Huh. Almost as if a company would provide a guarantee and only get paid if they kept the servers running for at least 99.999% of the time.

Weird, huh?

Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study

#130
post #107

Earlier quoted context omitted.

As a general rule, the entire medical profession has the incentives set up the wrong way - the more problems you have, the more they benefit. I have read that there was a time, in the distant past, where you paid a doctor only as long as you were healthy. I can come up with some problems even in that case, but I can't help but think it might still be an improvement over the current situation...

Except that it is simply not true - the world is not that simple. There are several incentives at play for a doctor. Obviously there are different fields, and dental is slightly weird compared to the others, but first of all, doctors are trained to help and learn cures . A doctor that keeps you sick instead of healthy is quickly out of a job (or out of patients, if you prefer). There are other doctors you know, and t…

Or even private insurance. There is a reason many insurance plans send you exercise right reminders all the time: healthy people cost less to ensure and so make more money.
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