Suppressing a gene by using its antibody can lead to tooth growth: animal study
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Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#2The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#3> They found, with animal studies, that suppressing the gene USAG-1 by using its antibody can efficiently lead to tooth growth.
And we're sure that suppressing USAG-1 (uterine sensitization associated gene-1) is safe?
Since this has "uterine sensitization" in it, it seems like it may affect more than teeth!
Just from a quick glance, this says its involved in pregnancy.
> Given the remarkably tight restriction of its expression, USAG-1 may be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction.
https://academic.oup.com/biolreprod/article/67/5/1638/268387...
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#4The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.
Just pull all teeth and let them regrow at the same time, of course. Next!
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#5The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.
Don't rodent teeth grow continuously anyway? That's why they're always gnawing on stuff.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#6So in a few decades I might have a choice between dentures or tooth regrowth? That'll be nice if it happens.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#7The article linked says it causes new teeth to grow in rats and ferrets, and that pugs and dogs are next. It doesn't however talk about targeting that growth to a particular place.
Just pull all teeth and let them regrow at the same time, of course. Next!
I know you're joking but theres actually people who would pray for a treatment exactly like this. The elderly in particular. Over time all your teeth go.
When I'm 60 I wouldnt mind them just ripping them all out if I could regrow them in 3 months.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#8So in a few decades I might have a choice between dentures or tooth regrowth? That'll be nice if it happens.
Maybe not that long. I'm 41 and have dentures. 18% of people 33-45 have them. 3% of people 18-33 have dentures.
I've got a full denture with implant posts on the top, and a partial on the bottom. It's not just a "given" that teeth will hold out till retirement age.
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#9[deleted]
Re: Suppressing a gene by using its antibody can lead to tooth growth: animal study
#10In mice.