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Japanese scientists develop vaccine to eliminate cells behind aging

japantimes.co.jp

341–350 of 382 posts

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#341

Earlier quoted context omitted.

Happiness is a direct co-relation to GDP. The growth of a civilization is directly as a result of GDP. For example being in nature brings you happiness. BUT this is only in well developed countries and among people with enough wealth to live comfortably. Money does not make you happy but it gives you much more opportunity to be happy.

> Happiness is a direct co-relation to GDP. The growth of a civilization is directly as a result of GDP. That’s actually not correct. By that argument the happiest country should be the United States as it has the largest GDP. However the United States ranks #19 on the World Happiness Report: https://worldpopulationreview.com/country-rankings/happiest-...

I should have been more specific: GDP per capita is one of the most important part of a person's happiness.

https://ourworldindata.org/grapher/gdp-vs-happiness

Chart above clearly shows that mostly increase in GDP results in higher life satisfaction.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#342

Earlier quoted context omitted.

Lots of money and no red tape.

I thought it was interesting that no country in the world did challenge vaccination trials despite there being many volunteers. I don’t know if I’d call that refusal red tape exactly but it’s in the neighborhood.

https://www.the-scientist.com/news-opinion/q-a-human-challen...

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#343

Earlier quoted context omitted.

>Economically and ethically, we should prioritize this research above most else. This research and all similar research (and sentiments like yours, which I strongly agree with) remind me of the classic Fable of the Dragon-Tyrant.[0] It feels as though we are finally on the cusp of learning the shape of the armaments that will one day slay the dragon. And I wish the world could band together the way we attacked COVID…

Surely could have been much shorter! An enjoyable parable but clearly written by a philosopher.

As opposed to that terse and highly popular Tall-Hammam paper, perhaps?

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#344

Earlier quoted context omitted.

Evolution can optimize for longer lifespans if it makes propagation more favorable. It happened in humans — grandparents make us more successful. Except when they run our governments.

We need to evolve past the point where we expect to rely on government.

A benevolent Government is just Society. Nothing wrong with society.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#345

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

In an ideal world. Even if we achieve longevity with this approach, we can't use it for everyone. People need to die now more so than ever, where would we put them otherwise? The whole idea behind the current pandemic is that people need to die, via vaccines, or the virus, or the media.

> we can't use it for everyone.

Obviously it should only be used by the poor, so they have longer to find happiness. Someone has to blow the horn and push the wheelbarrows.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#346
post #260

Earlier quoted context omitted.

Lots of money and no red tape.

Red tape in the medical trials domain is forged from blood. Human experimentation is limited and carefully managed for very good reasons. Killing people to extend other people's lives is not a good tradeoff.

Wouldn't say otherwise, I don't necessarily agree it's a good idea.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#347
post #326

Note that these mice were fed a high fat diet (HFD), essentially toxic fat overload to generate disease phenotypes that one can demonstrate an improvement in. Mice normally eat a mainly grain based diet, so getting 45% of calories from fat is as you can imagine pretty bad for them. This is a common theme in anti-ageing research. When you administer some cariacature of poor lifestyle, it is much easier to find ways to…

Doesn't sound too different from the diet a lot of humans eat ;)

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#348

Earlier quoted context omitted.

You forgot tiny detail that they live in prison for entire life eating equivalent of Mc Donalds or worse.

by mouse life standards, they live like kings

You mean, by what some humans think is mouse standard.

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#349

1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…

>>Economically and ethically, we should prioritize this research above most else.

Sure, f*ck climate change, let's just live and suffer longer

Re: Japanese scientists develop vaccine to eliminate cells behind aging

#350

Earlier quoted context omitted.

Lonelyness seems to be a problem of social institutions rather than physical defficiency?

I would argue that it’s neither, rather I believe that the issue is how society disproportionately worships youth.

"society disproportionately worships youth."

Does it really? The derision of millenials seems never ending, along with 'kids these days' and 'back in my days'.

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