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Is there a good resource to learn more about this without a Biology degree? I always assumed the body generated matching snippets at random and the law of large numbers would result in a match eventually.
This book was written by makers of the Kurzgesagt's YouTube channel recently. https://www.amazon.com/-/es/gp/aw/d/0593241312/ref=tmm_hrd_s... Pretty cool illustrations too.
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Really? Because they get experimented on and then slaughtered by the thousands
You forgot tiny detail that they live in prison for entire life eating equivalent of Mc Donalds or worse.
2. I believe all governments should create Warpspeed for this approach. At the depths of covid lockdowns, GDP was down 20%. Imagine the massive GDP creation from making every 65+ year old feel 40 again. They'd work, consume, and generally flourish. Even if it's only 10 more years of quality life, this is the greatest good that could be done for humanity. To avoid another 10 years of my parents death is something I'd do a lot for. Economically and ethically, we should prioritize this research above most else.
3. This approach is scientifically sound. Certain aspects of aging cures are approaching engineering levels of work rather than pure science. We simply know that many diseases are caused or amplified by senescent cells. And we have ample evidence that elimination of these cells reverses diseases in complex mammals, as long as you don't remove too many, too quickly. The rest, is the engineering problem of how to remove the right cells at the right cadence.
4. This is the kind of thing biohackers should hack on. Find an aging part of your skin, and attempt to convince your body to kill the senescent cells. If you succeed, you will have benefited humanity, become beautiful, become wealthy, and be remembered forever (is there any other fundamental need humans have, not covered)?
Let the race begin!
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This would be like being worried about playing outside and being exposed to germs. Yes, it’s true that every new infection has the possibility of killing you. But, now we have evidence that exposure to diverse mild pathogens actually makes your immune system less dangerous to the self. Otherwise it would be safer to live in a clean room.
I agree you should not try to live in a clean room, and you shouldn't be worried about being exposed to normal amount of germs. When you say "exposure to diverse mild pathogens actually makes your immune system less dangerous to the self", I suspect you're referring to the hygiene hypothesis that has become part of popular culture. It's important to know that that hypothesis, nowadays, is about early exposure to beni…
Sign me up for this the second it is available. As an aside, to spite anti vaxxers I’m on a mission to get every vaccine I can. I want my bloodstream to be like the Library at Alexandria before it burned down.
I hope this is satire. The medical industry doesn’t always have your best intentions at heart. From talcum powder to thalidomide. Be careful.
1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…
This research and all similar research (and sentiments like yours, which I strongly agree with) remind me of the classic Fable of the Dragon-Tyrant.[0] It feels as though we are finally on the cusp of learning the shape of the armaments that will one day slay the dragon. And I wish the world could band together the way we attacked COVID to attack this problem.
>the king answered in a broken voice: “Yes, we did it, we killed the dragon today. But damn, why did we start so late? This could have been done five, maybe ten years ago! Millions of people wouldn’t have had to die.”
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Really? Because they get experimented on and then slaughtered by the thousands
You forgot tiny detail that they live in prison for entire life eating equivalent of Mc Donalds or worse.
Though 1/3 of my meals are Soylent, so even that doesn't seem entirely terrible.
1. Removing senescent cells extends life by 30-40% with huge quality of life improvements in the last 25% of the life (relative to control), in mice. This isn't an elimination of all aging, but quite a valuable thing regardless. Eventually, other causes of aging would kick in and still cause death, without a single senescent cell in your body (e.g. DNA methylation). 2. I believe all governments should create Warpspee…
So less jobs for young people.
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Definitely. We have a tremendous amount of risk aversion these days and a culture that has disdain for risk, even calculated abstract risks. What many don't realize is being too risk averse comes with its own risks, it also requires accurate risk assessment so you can make the correct decisions on when to take a risk and not. You could lockup in complete fear akin to analysis paralysis where non-zero risk keeps you f…
A few "yes, but..."s: > If you're not traveling outside the US and living a fairly normal life Globally, given an at-least-middle-class lifestyle (and any other years than 2020–2021), "not travelling outside [your home country]" is actually rather abnormal. It's mostly an American thing. I've seen it hypothesized that higher risk-aversion from a media-inculcated culture of fear could be responsible for Americans' uni…
Japanese people don't leave Japan much either. And between those two countries we've now called half the developed world "abnormal". It may be just as accurate to say Europe is the outlier, especially when you consider all of humanity and all of civilized history. Also it obviously depends where people travel to, developed or otherwise.
Either way though, the vaccination recommendations in the US (as I'm sure every country) vary depending on whether you plan to travel or not. There isn't a fixed policy for everyone, at least when it comes to recommendations.