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Sperm Count Dropping in Western World

scientificamerican.com

291–300 of 300 posts

Re: Sperm Count Dropping in Western World

#291
post #74

My belief is that the primary cause is environmental chemicals, specifically Phthalates and BPA (and related chemicals). The science on this is fairly conclusive. We can show that these chemicals bind to estrogen receptors, that they're present in everyone's body, and that if you're acutely exposed to a higher dose, your testosterone goes down. In my opinion, these chemicals are having social and cultural effects bey…

The linkage between consumption of these chemicals, and their exact nature of harm, is not well established- it's not "fairly conclusive" at all. What we have is a bunch of in vitro and in vivo studies, but not actual epidemiological evidence of the quality required to make rational policy decisions. If you believe otherwise, I'm happy to ready any high quality studies you can find. Pleaes don't just cherry pick a fe…

I don't know what would convince you that at minimum, these chemicals should be taken out of food contact applications or heated up and volatilized in thermal printers, and then handed to a customer.

Just picking articles at random, I don't have time for a full literature review for Hacker News, but the evidence taken in totality is overwhelming:

1. BPA (and related chemicals) activate estrogen receptors, causal study: https://www.ncbi.nlm.nih.gov/pubmed/28407500 This has been repeatedly demonstrated.

2. Direct human effects, correlational study: Working in a factory with BPA makes you impotent: http://www.oxfordjournals.org/news/dep381.pdf

3. Direct human effects, correlational study: BPA exposure by parents, especially mothers leads to reduced anogenital distance in children: https://www.ncbi.nlm.nih.gov/pubmed/21987463

4. Direct human effects, correlational: BPA and other EDCs are associated with penile defects: http://www.acmt.net/_Library/PEHSU_Webinars/Is_Hypospadias_A...

5. Human ingestion routes, correlational: Blood BPA levels are highest occupationally among cashiers (thermal receipts), and people who eat a lot of canned vegetables (plastic can liners): https://www.ncbi.nlm.nih.gov/pubmed/21205581

There are loads more where that came from. You've got a very direct mechanism of action, clear effects in animal models, and correlational studies showing people who are exposed to larger quantities show clear medical problems. You have clear, understandable routes of ingestion, and correlational data that shows that people who are exposed more to those routes of ingestion have more in their blood. I suppose you can complain that the human studies are correlational, but you can't legally perform a blinded study on this, because we know that BPA is harmful, and you won't get it past an IRB. Maybe you formed your opinion on this in the nineties or 2000s when only the hippies were trading out their nalgene bottles, but the science has come a long way, and the hippies were right. Phthalates are a very similar story.

Re: Sperm Count Dropping in Western World

#292
post #256

Earlier quoted context omitted.

The scientific process has also led to chemicals such as Thalidomide to be given to pregnant women, resulting in 10000 babies born with phocomelia. The point is not to be overly confident with what you think a chemical can do to your body, even if it is approved by the FDA.

Imperfect information and lack of tools/knowledge to perform adequate analysis, and perhaps selfish motivations might have caused Thalidomide to be given to pregnant women, but the scientific process did not. Unless you can pinpoint all the causal factors of a relationship, there is no other option I have heard of other than the scientific process, i.e. testing, calculating, re-testing, calculating, retesting...etc t…

I agree there is no better option but that is not sufficient to no longer doubt the state of the art knowledge of biomedicine or effects of chemical on the body.

Re: Sperm Count Dropping in Western World

#293

Earlier quoted context omitted.

I think I fear that marketing forces are stronger than consumer knowledge. I spend too much time debunking facts on Facebook posted by relatives to think that people in general want to spend time looking for the truth. Also we have studies that shows that doctors doesn't understand enough statistic to understand medical studies and make good choice. I also see that ordinary folk don't discern the difference in knowle…

>I think I fear that marketing forces are stronger than consumer knowledge. I fear regulations for that reason. If political marketers convince voters to elect some puppet for special interests, who imposes regulations mandating I use some inferior product, by prohibiting all other options, I have no way to opt out. I trust the ability of people to see through marketing lies when it's in the context of an organic mar…

I think you are quite correct to point that law and regulation reduces personal autonomy and that the law is violent in is nature. I agree 100% that the impact of marketing on the result of election and it scares me a lot the new trend to use social mass data to win election. I m more and more in favor of sortition for this reason. I agree also that you have regulation set up by people that seek rent above everything.

I think I fear also the harm that powerful people or corporation do right now and I think someone need to take action. What is difficult is to have the right balance between liberty and regulation.

We see a division between continental Europe and Anglo-saxon country; In Europe we have more regulation and I think less economical growth and less innovation and the US where it seems you have less regulation but often more meant to create rent and crazy companies behavior but you have growth and more innovation.

Thanks for your comments, it s nice to have a good conversation :)

Re: Sperm Count Dropping in Western World

#295
post #166

Turns out modernity is an extremely unhealthy environment for humans, especially men. Despite the narratives being thrown at you, we live in an incredibly "feminized" society where social stigma/violence/shaming are more powerful for the average person than plain old physical violence.

> Turns out modernity is an extremely unhealthy environment for humans, especially men.

Not modernity. Modern western society may be hazardous to men. For all the talk about male privilege, the society seems to be geared towards keeping men down and lifting up women.

Of course the male elites seem to be doing well, but generation by generation, the non-elite males have had their status/wealth/income/etc drop relatively speaking.

> Despite the narratives being thrown at you, we live in an incredibly "feminized" society where social stigma/violence/shaming are more powerful for the average person than plain old physical violence.

Absolutely agree with you on this. Instead of men physically beating women, now the violence is social/societal/governmental/etc. Where laws are created to favor women over men. Where women attack men by calling men "sexist/bigoted/aggressive/etc".

There probably is an environment component to this issue. But there is probably a social/societal component to this as well. Being attacked by society since birth probably negatively affects the male population in the west.

Certainly, the concerted effort by the elite to effeminize the western male for the past many decades has to have contributed.

Re: Sperm Count Dropping in Western World

#296
post #292

Earlier quoted context omitted.

Imperfect information and lack of tools/knowledge to perform adequate analysis, and perhaps selfish motivations might have caused Thalidomide to be given to pregnant women, but the scientific process did not. Unless you can pinpoint all the causal factors of a relationship, there is no other option I have heard of other than the scientific process, i.e. testing, calculating, re-testing, calculating, retesting...etc t…

I agree there is no better option but that is not sufficient to no longer doubt the state of the art knowledge of biomedicine or effects of chemical on the body.

The scientific process is all about doubting what you "know"...obviously to be pragmatic, it's useful to assume certain things such as gravity, time, that a chemical reaction yesterday will do the same today under the same conditions, etc. But the whole purpose of testing and retesting (which is the scientific process) is because you're always doubting.

That's why data should be free, in order to let this testing happen. Of course we have limited resources to do testing, so there must be some triage involved somehow, but that has nothing to do with the scientific process.

Re: Sperm Count Dropping in Western World

#297

Earlier quoted context omitted.

>I think I fear that marketing forces are stronger than consumer knowledge. I fear regulations for that reason. If political marketers convince voters to elect some puppet for special interests, who imposes regulations mandating I use some inferior product, by prohibiting all other options, I have no way to opt out. I trust the ability of people to see through marketing lies when it's in the context of an organic mar…

I think you are quite correct to point that law and regulation reduces personal autonomy and that the law is violent in is nature. I agree 100% that the impact of marketing on the result of election and it scares me a lot the new trend to use social mass data to win election. I m more and more in favor of sortition for this reason. I agree also that you have regulation set up by people that seek rent above everything…

Beyond the intellectual debate on net economic effect, we should have the humility to not punish people with legal penalties for actions that are fundamentally voluntary.

Re: Sperm Count Dropping in Western World

#298

Isn't this good anyway? Because of overpopulation?

No! Low population growth leads to a smaller labour force, and a growing elderly demographic. It's not a solution to overpopulation.

Having an increasing number of kids to ensure pensions are paid doesn't seem good for overpopulation issues either.

Re: Sperm Count Dropping in Western World

#299

Earlier quoted context omitted.

> potential dangers of every synthetic chemical I wouldn't put too much importance on the synthetic / natural distinction. Lead, tobacco, and various radioactive elements (uranium, radium, thorium, and radon) are all perfectly natural. If you were harmed by chemicals in the last century, it was probably one of them. There are also thousands of lab-made chemicals that never make the news because they're just not harmf…

"natural" is in some ways a proxy for "understood". We know lead, tobacco, and radiation are toxic. We have hundreds of years of evidence. On the other hand brand-new man-made chemical X that was just invented yesterday has no track record whatsoever. We just don't know. I try to read food labels, and it's exhausting trying to keep up with all the new chemicals they put in food (or in furniture, or plastics, or whate…

I'm not opposed to proxies, I just think "anti-synthetic" is a particularly bad one. Synthetics are so frequently protective that avoiding them is more likely to do harm than good.

A better heuristic might be:

Humans worry too much.

Or:

Don't invent heuristics that scientists working in the relevant field think are unnecessary.

Toxicology is full of smart people learning things on our behalf. They have models and simulations and labs to scrutinize new chemicals for us, or even just to avoid massive class action lawsuits.

Among their findings is the fact that we can't seem to make anything nearly as toxic as nature can. Even when we try we come up short by a factor of like a freaking million:

https://blogs.scientificamerican.com/guest-blog/natural-vs-s...

If you want simple guidelines to save time with groceries: avoid lunchmeats to reduce your risk of (natural) listeria, cook your chicken to avoid (natural) salmonella, don't can your own food to avoid (natural) botulism, and call it a day.

Or maybe don't worry about toxins at all, because they kill statistically almost no one, and instead: work out, eat some leafy greens, avoid obesity, smoking, drinking, guns, and unnecessary car trips.

At that point you're so far in the lead that if you die from a random chemical, just shake your fist at the gods and die knowing you did far more than most people. If you do die from a chemical, you didn't die from not being smart, you died from not being lucky, and could have easily been crushed by a meteor.

Re: Sperm Count Dropping in Western World

#300
post #211

Earlier quoted context omitted.

The burden of proof should obviously be reversed! Complex, synthetic chemicals in our water, food, packaging, or furniture should be assumed harmful and disallowed until it there is sufficient evidence that they are safe. Escalating trials basically. This is what we do for pharmaceutical drugs that we ingest or contact, why don't take this approach with other man-made chemicals we are adding to our immediate ecosyste…

Our diet is full of fruits and vegetables containing thousands of complex chemicals, indistinguishable from "synthetic" chemicals, that have entered our diet far too short a time ago to have had evolutionary impact. If one wanted they could surely distill many chemicals in isolation from these naturally occurring fruits and vegetables that in concentration would have many concerning health effects. The fact that many…

>Our diet is full of fruits and vegetables containing thousands of complex chemicals, indistinguishable from "synthetic" chemicals, that have entered our diet far too short a time ago to have had evolutionary impact.

Our diet of fruits and vegetables has been refined through thousands of years of trial and error, and the result is that we eat a tiny fraction of available plants. It's arrogant to dismiss that history.

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