So people on a vegan diet ( low in taurine ) will live shorter?
Taurine deficiency as a driver of aging
251–260 of 301 posts
Re: Taurine deficiency as a driver of aging
#252Earlier quoted context omitted.
By the way: A 16 oz can of Monster contains 2 grams of taurine. My first thought when I reading your post (before I finished): How many grams of taurine per kilogram of body weight were used in the trial? I found: Taurine supplementation increases the life span of mice To determine whether the observed drop in taurine concentration contributes to aging, we orally administered control solution or taurine at 1000 mg pe…
>1000 mg per kg body weight 1g/kg body weight daily of ANYTHING is A LOT. 0.1% of your entire bodyweight. What's interesting is I checked Wikipedia and found: https://en.wikipedia.org/wiki/Taurine >accounts for up to 0.1% of total human body weight >The mean daily intake from omnivore diets was determined to be around 58 mg So this study is adding the entire amount found in a typical human's bodyweight every day.
1g/kg is 1%.
Re: Taurine deficiency as a driver of aging
#253Isn‘t any deficiency a driver of aging?
Re: Taurine deficiency as a driver of aging
#254So people on a vegan diet ( low in taurine ) will live shorter?
„However, prolonged intake of a vegan diet with negligible taurine content leads to a decline of only ∼20% in circulating taurine in young healthy individuals (6, 7), suggesting that the ∼80% decrease observed in older people by Singh et al. at least partly reflects a loss of capacity for endogenous synthesis“
Re: Taurine deficiency as a driver of aging
#255Earlier quoted context omitted.
>1000 mg per kg body weight 1g/kg body weight daily of ANYTHING is A LOT. 0.1% of your entire bodyweight. What's interesting is I checked Wikipedia and found: https://en.wikipedia.org/wiki/Taurine >accounts for up to 0.1% of total human body weight >The mean daily intake from omnivore diets was determined to be around 58 mg So this study is adding the entire amount found in a typical human's bodyweight every day.
1g/kg is 1%.
It's 0.1%
Re: Taurine deficiency as a driver of aging
#256Don‘t miss out the related perspective article on this: https://www.science.org/doi/10.1126/science.adi3025
It discusses important issues like
„ A key issue for any longevity intervention is whether it causes calorie restriction (which can extend life span) or acts through independent mechanisms. Singh et al. found that taurine supplementation did not affect food intake in mice but nonetheless caused a small decrease in body weight, indicating a calorie deficit. Energy expenditure was higher in taurine-treated mice and intestinal transit time was accelerated, although it is not clear if nutrient absorption was decreased. The change in intestinal behavior is intriguing, because taurine is conjugated to bile acids to form bile salts, which facilitate uptake of dietary lipids (1). It will be crucial to control for the effects of taurine on body composition and nutrient uptake in future studies.“
Re: Taurine deficiency as a driver of aging
#257Re: Taurine deficiency as a driver of aging
#258Earlier quoted context omitted.
WHy does it have Taurine? I honestly don't know why any of the non-caffiene non-b vitamin ingredients are in "energy drinks" like Taurine.
According to GPT4 there's research indicating that taurine increases metabolism, improves athletic performance, helps regulate neurotransmitters (so could be construed to improve cognitive functioning), and improves cardiovascular health. I'd wager you can't conclude from any of that research that putting a gram of it in a drink will help with anything at all, but from a marketing perspective it's a name that carries…
GPT4 is not a search engine. Please stop.
Cite sources or don't do this.
Re: Taurine deficiency as a driver of aging
#259Earlier quoted context omitted.
> Jokes aside, This feels like one of "Wine is Good for you" In moderation and other fine point details. Not buying it. I mean, pinot noir has a lot of resveratrol. You'd just need 750-1000 glasses daily.
AFAIK, at this point resveratrol does not look promising.
David Sinclair wrote in "Lifespan"[1] that they extended mice lifespan by (iirc) something like 40% but amounts of resveratrol used was something like mentioned 750-1000 wine glasses daily when translated to humans.
While Wikipedia suggests that resveratrol is not proven to help with anything, I'm still taking 600mg in the morning, along with 600mg ALA and 100mg of CoQ10. Placebo is an effect, too.
[1] https://en.wikipedia.org/wiki/Lifespan%3A_Why_We_Age_%E2%80%...
Re: Taurine deficiency as a driver of aging
#260Earlier quoted context omitted.
Standard intake of taurine in most people is <200mg a day. That would be an astounding amount of taurine. Also, it's a little weird because humans can synthesize taurine, it's a major component of bile, so I'm unclear what mechanism could cause supplementation to have significant effects.
There are a lot of amino acids which the human body can produce that nonetheless show clinical effects when additional amounts are ingested. I don’t understand the logic either but I’ve decided the human body has a billion things yet unknown to science so I take macro effects at face value even if I can’t learn an underlying mechanism for them. As a side note, a lot of weightlifters believe taurine reduces muscle cra…
Maybe there's a benefit to not needing to spend the energy or raw materials needed to synthesize something yourself? The large amounts needed might reflect that outsourcing the production is inefficient.