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Taurine deficiency as a driver of aging

science.org

221–230 of 301 posts

Re: Taurine deficiency as a driver of aging

#221

In the study mice were given 1000 mg taurine per kg body weight per day. In comparison a typical taurine supplement for humans is 1000 mg total . IOW they gave the mice a dose of taurine that, proportionally, i'd be unwilling to take.

1000 mg ... you mean a gram :-) ?

he meant 0.001 kg

Re: Taurine deficiency as a driver of aging

#224

Earlier quoted context omitted.

Yes, I know this. However you're making the blanket statement that it's harmless, and I simply have to push back on that. If it affected me this negatively, it's surely causing harm to others.

I mean my wife is allergic to lactose, but I wouldn't say lactose is anything but generally harmless.

"...but I wouldn't say lactose is anything but generally harmless."

Obviously you've never lain (I cannot call it sleep) with a lactose-intolerant SO after an evening of milk-laden feasting (loves Indian desserts which, with Indian meal included, ratchets up the noxious undercover methane emissions by about 10,000%). The dog even moved out of the bedroom!8-((

Re: Taurine deficiency as a driver of aging

#225

Earlier quoted context omitted.

Standard intake of taurine in most people is <200mg a day. That would be an astounding amount of taurine. Also, it's a little weird because humans can synthesize taurine, it's a major component of bile, so I'm unclear what mechanism could cause supplementation to have significant effects.

I know of a condition that seems to involve inadequate bile production. So hypothetically, it could help in that case.

I know of one that is probably quite common: excess liver fat. Also if you costume crazy low amounts of fat you could probably get low bile production (as in fruitarian low, not whole foods plant based low).

Re: Taurine deficiency as a driver of aging

#226
post #165

I order stuff off the Internet from time to time including taurine, is there an easy/cheap way to test things that come through the post from Amazon or another company are Taurine and don’t contain things they shouldn’t? The supplement industry strikes me as dubious! Is there a better way to think about this?

Order from a trusted pharmacy, rather than from 3rd parties like Amazon. With the way binning works at Amazon, you can't trust that you will get a legitimate product even if you ordered the same thing you made sure was legitimate last time.

You may be correct, but I doubt there is a high enough profit for such a cheap supplement to be counterfeited and sold 3rd party.

Re: Taurine deficiency as a driver of aging

#228
post #71

Earlier quoted context omitted.

You probably can live longer if you stick with coffee (black), berries (minus the food you put the berries on top of), dark chocolate (unsweetened), and wine (in strict moderation).

Alcohol is a carcinogen, so if you’re optimizing for “living longer” you should take exactly 0 mL a day. If you’re optimizing for living happier, on the other hand…

Oxygen is a carcinogen, now what...

Re: Taurine deficiency as a driver of aging

#229

Earlier quoted context omitted.

By the way: A 16 oz can of Monster contains 2 grams of taurine. My first thought when I reading your post (before I finished): How many grams of taurine per kilogram of body weight were used in the trial? I found: Taurine supplementation increases the life span of mice To determine whether the observed drop in taurine concentration contributes to aging, we orally administered control solution or taurine at 1000 mg pe…

Standard intake of taurine in most people is <200mg a day. That would be an astounding amount of taurine. Also, it's a little weird because humans can synthesize taurine, it's a major component of bile, so I'm unclear what mechanism could cause supplementation to have significant effects.

There are a lot of amino acids which the human body can produce that nonetheless show clinical effects when additional amounts are ingested.

I don’t understand the logic either but I’ve decided the human body has a billion things yet unknown to science so I take macro effects at face value even if I can’t learn an underlying mechanism for them.

As a side note, a lot of weightlifters believe taurine reduces muscle cramps.

Re: Taurine deficiency as a driver of aging

#230

In the study mice were given 1000 mg taurine per kg body weight per day. In comparison a typical taurine supplement for humans is 1000 mg total . IOW they gave the mice a dose of taurine that, proportionally, i'd be unwilling to take.

> Serious adverse effects have not been reported with taurine supplementation.[24] The highest dose used in a human trial was 10 grams per day for 6 months, and the longest human trial was 12 months and used a dose of 0.5–1.5 grams per day. Based on the available evidence, it’s suggested that 3 grams per day can be consumed indefinitely without risk of side effects.[24]

https://examine.com/supplements/taurine/

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