Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Marijuana accelerates growth of HPV-related head and neck cancer (2020)

health.ucsd.edu

Post reply on HN
Print view View original

111–120 of 146 posts

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#111

Post by throwanem »

ChrisLomont wrote: post #95
paulsutter wrote: post #91

Why most published research findings are false: https://en.m.wikipedia.org/wiki/Why_Most_Published_Research_...

That study has been debunked. For example, in it he guesses at some factors fundamental to his thesis. Later studies to empirically measure those factors found his guesses to be wildly incorrect, and correcting for the empirical data, Ioannis claims are found to be unsupportable.

Debunked where, by whom? Not that Ioannidis isn't a publicity hound of the first water, but if nothing else it'd be useful to have cites for the next time this comes up.

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#112

Post by moron4hire »

SuoDuanDao wrote: post #106
vasco wrote: post #79

Earlier quoted context omitted.

It also is, children shouldn't be misled by their parents about scams like healing crystals because they will believe it as they are children. Later in life they might resort to crystals instead of getting medical attention.

I'm far more worried by children being misled by their parents about scams like stimulants instead of meditation. I've never heard of someone developing a dependancy on a crystal.

Depends on the crystal. Crystal meth, for example.

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#113

Post by avs733 »

intricatedetail wrote: post #87
avs733 wrote: post #86

Earlier quoted context omitted.

“ Cannabinoids Promote Progression of HPV-Positive Head and Neck Squamous Cell Carcinoma via p38 MAPK Activation” That is the study name. You are referencing the title of the press release from the university they work at. While it’s perfectly fair to discuss the historical context of words, it’s important that we also recognize that using commonly used terminology in translating science for public consumption is nec…

The N word is also commonly used, doesn't mean it's right. There should be no place for racism in academia. I am surprised this is up since 2020.

did you really compare saying Marijuana and a word you won't say?

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#114

Post by buescher »

ChrisLomont wrote: post #95
paulsutter wrote: post #91

Why most published research findings are false: https://en.m.wikipedia.org/wiki/Why_Most_Published_Research_...

That study has been debunked. For example, in it he guesses at some factors fundamental to his thesis. Later studies to empirically measure those factors found his guesses to be wildly incorrect, and correcting for the empirical data, Ioannis claims are found to be unsupportable.

A fair criticism of Ionnidis would be "statisticians always knew this about every field that reports statistical significance with p-values, but no one was going to listen, I don't know what that guy's got". I'm not aware of any substantive "debunking" of his famous paper, which is not a "study".

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#115

Post by smokelegend »

StreamBright wrote: post #62
TedShiller wrote: post #21

Earlier quoted context omitted.

Yep, cannabis seems like the solution for a lot of random things (various confounding diseases, including depression, etc) until you look at the possible long-term effects. Those are usually conveniently ignored. I get it though. The guy hyping and selling you cannabis is not going to be dealing with your long-term effects in 20 years.

Kind of how it was ignored for opioids in the US.

Or benzodiazepines in the 60's - 70's

https://pubmed.ncbi.nlm.nih.gov/24007886/

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#116

Post by asdfasgasdgasdg »

sitkack wrote: post #48
asdfasgasdgasdg wrote: post #32

Earlier quoted context omitted.

You can get it up 'til you're 45 (after that it's not approved), but you have to ask. My understanding is most adults have already been infected, so it is not considered very important to vaccinate them. If you haven't had any or many sexual partners, I reckon it could make sense to get it even if you're not a teen any more. On the other hand, if you've been with more than a handful of people, you've probably already…

I don't think you should be advising people to NOT do things unless it is actively unsafe.

I did not advise inaction at any point in my comment. I conveyed some information about why health policy has the configuration it currently does.

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#117

Post by asdfasgasdgasdg »

refurb wrote: post #39
asdfasgasdgasdg wrote: post #27

Earlier quoted context omitted.

Gardasil 9 hits enough of the HPV variants that the rate of cancer-causing HPV infections has fallen by 90% in the US. And that's with the fraction of folks who are anti-vaxxers taken into account. This is one of those diseases where the means to prevent being infected is already in hand.

Do you have a source for the 90% reduction? It can only be given to teens so most people haven’t gotten Gardisil and if you already have HPV (most do) it doesn’t make it go away.

https://www.cdc.gov/hpv/parents/vaccine-for-hpv.html

"Among teen girls, infections with HPV types that cause most HPV cancers and genital warts have dropped 88 percent."

This isn't exactly the same statistic as what I said, since not all HPV infections occur during teenage years. But this is the statistic I was referring to. Apologies for my imprecision.

Re: Marijuana accelerates growth of HPV-related head and neck cancer (2020)

#120

Post by selimthegrim »

Terry_Roll wrote: post #78
pmoriarty wrote: post #41

Though this study did not focus on other cancers, THC's adverse effect might not be limited to just HPV-related head and neck cancer. From the paper[1]: "Similar to CNR1, the cannabinoid receptor CNR2 was also found to be highly expressed and correlated with worse prognosis in tumors such as breast cancer (16), renal cancer (17), lung cancer (51), and HNSCC (21). In our study, the expression of CNR2 mRNA was upregula…

You might want to ask your medical expert about this. Penicillin based anti biotics break down into penicillamine https://wikidiff.com/penicillin/penicillamine "penicillamine treatment relies on its binding to accumulated copper and elimination through urine." https://en.wikipedia.org/wiki/Penicillamine "Copper deficiency reduces interleukin-2 (IL-2) production and IL-2 mRNA in human T-lymphocytes" https://pubmed.ncb…

Wouldn’t you want to stay copper depleted? I don’t follow.
Post reply on HN