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Calorie restrictive eating for longer life? The story we didn’t hear in the news

junkfoodscience.blogspot.com

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Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#31
post #20

Earlier quoted context omitted.

Slack and crud?

I'm paraphrasing because I'm not a scientist. Slack = various sorts of resources, including immune resources. Crud = inter- and intra-cellular unwanted buildup of proteins, failing cells, non-reversible damage, yadda yadda. It all gets torn up and coincidentally cleaned up by the body's panic for materiel.

If that's the case, intermittent fasting seems like it should produce similar effects to CR. I wait with bated breath for the experiment that does intermittent CR on mice. :)

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#32
post #8

Earlier quoted context omitted.

I haven't read the studies. Still, why isn't it reasonable to think that a monkey that eats too little will die more readily under stress? You can remove clearly unrelated causes (e.g. monkeys run over by bicyclists), but it's not nearly so clear for anesthesia.

Because the monkeys weren't being underfed and it's a straw man to suggest they were. Tibetan monks get by on much less food than we do and they will still kick our asses anytime.

In the caloric restriction experiments, the nutritional density of the food the animals are fed is almost always increased. Fewer calories, same levels of protein, nutrients, etc. It's not just a matter of 'less'.

From what I've read, humans on caloric restriction diets have to design their diets carefully, to increase the nutritional density of their own food supply. (E.g. http://www.calorierestriction.org/Getting_started)

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#33
post #19
post #13

One of the few negative things about the growth of the internet is how much people rely on it for health information. Sometimes I think they'd be better off flipping a coin.

You can get a lot of flaky diet fads from women's magazines, too.

I don't know if its just me who's noticed this, but if one pans out and takes an overview of the main diet fads over the past 30 years, one will notice that the main focus of a diet changes every 10 years or so.

Recall in the 90's when everything was "low-fat". Starting somewhere in the 2000's the health industry switched it over to "low-carbs".

In the 80's, if one wanted to build muscle they were told to eat as many carbs as possible. Nowadays one is supposed to eat as much protein as possible.

This is just diet information. Methods of exercise change too. In fact, they sort of cycle in a way.

Ever feel like the health industry is trying to pull one over on you?

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#34

The article in Science concludes with this: "Weindruch and his collaborators plan to continue monitoring the remaining monkeys, which could stretch the study's length past 3 decades. "If we reach the 40-year-old life span, the study could continue for another 15 years," Weindruch said." The NY Times article says: “Ultimately the results seem pretty inconclusive at this point,” Dr. Austad said. “I don’t know why they…

I don't see how prudent it is. What can I do with that information, given the rest of the results of the study?

I don't have anything against diabetes, cancer or heart/brain disease per se. It's not as if, when I die from an infection or pneumonia, I'll congratulate myself that it wasn't cancer!

I guess what I'm trying to say is that, if you consider it "prudent to note the reduced rate of diabetes, cancer, and heart/brain disease", then my response is it's just precisely as prudent to note the increase in non-diabetes, cancer, and heart/brain disease related deaths.

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#35
post #20

Earlier quoted context omitted.

Slack and crud?

I'm paraphrasing because I'm not a scientist. Slack = various sorts of resources, including immune resources. Crud = inter- and intra-cellular unwanted buildup of proteins, failing cells, non-reversible damage, yadda yadda. It all gets torn up and coincidentally cleaned up by the body's panic for materiel.

Last time I check slack and crud ("Schlacken" in German) were very popular with quacks and diet fads, but had no science behind them.

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#36
post #5

I take issue with much of what was said in this article. Many, if not all of the examples the author refers to are explicit in there statements and not being vague. Additionally, the results of the studies are available for review and carefully explain the reasons why some deaths were not inluded in the results. The author is picking apart chosen pieces of text and apparently has not read the actual study results.

What are you talking about? He linked to the study and priced it out for you, but he didn't read it? The article compared the actual findings of the study with what was reported in the media and press releases.

I don't care how careful they were in explaining why they vacated many of the deaths; if you're trying to show that monkeys live longer on calorie restricted diets, you can't do that. At least, you can't if you want to convince me or most rational people.

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#37
post #12
post #3

Summary: junk science reported by junk press.

You really think a blog post is enough to justify this conclusion? Here, read the journal article: http://www.scribd.com/doc/17316946/Caloric-Restriction-Delay... Please tell me how it's junk science.

Are you serious? How about this part right here in the study title:

Caloric Restriction DELAYS Disease Onset AND MORTALITY in Rhesus Monkeys

...combined with the fact that in the contents of the study you link to, they eliminate significant data points whose presence would contradict the claimed delay in mortality.

I guess we'll all have to judge for ourselves whether it's fair to eliminate a bunch of deaths other than for exceedingly obvious reasons, e.g., someone breaks into the lab and kills the monkeys. I know which side I'm on.

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#38
post #24

I've heard a talk recently by a guy who works with scientists who do calorie restriction experiments. What he said is an eye-opener. The animals look healthier but they don't live longer. They don't seem to die of age, but they do just drop dead one day, not always from any obvious cause at all - although they seem particularly susceptible to infections. His hypothesis was that calorie restriction works by forcing th…

What a wonderful... anecdote.

Why the downvotes? It's absolutely true. "I heard something" is not a proper argument, and the claim that CR has no effect on lifetime is at odds with everything I've heard on the matter. One of my friends (Chemistry PhD) is crazy about the subject, has read all the studies and he's very excited about the insight CR discoveries may bring.

So .. harsh but fair. Anecdotes are worthless. Source please. And cdr should be rewarded, not punished, for calling it out.

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#39
post #8

Earlier quoted context omitted.

could have links to their diet Replace that with could have been caused by aliens to see how ridiculous that sort of claim is. There is no reason to suppose that dying under anesthesia is related to the diet. Also your analogy doesn't make any sense. Perhaps if they removed bikers that died in traffic accidents while not riding a bike . And then you could argue 'bikers behave differently in traffic, so perhaps biking…

I haven't read the studies. Still, why isn't it reasonable to think that a monkey that eats too little will die more readily under stress? You can remove clearly unrelated causes (e.g. monkeys run over by bicyclists), but it's not nearly so clear for anesthesia.

Do you really think your casual pondering of the matter has revealed an insight not obvious to the experienced, professional scientists who designed and are now running this large scale, multi-decade experiment?

It beggars belief they have not considered, and painstakingly controlled for, such factors.

Re: Calorie restrictive eating for longer life? The story we didn’t hear in the news

#40
I do not know what I am talking about when it comes to this topic. Neither, it seems, do most others here. We are intelligent laymen, but laymen all the same. So what do we do in order to intelligently judge this blog post?

Well, first, let's consider what we know about the contenders. On one side, a number of respected professional scientists conducting a very expensive multi-decade study and publishing the results in peer-reviewed journals. On the other side, a nurse with a Blogspot blog.

OK, that is not necessarily bad. Great truths have been spoken by nobodies. We judge by the message, not the speaker.

But still, we need more "meta" information. Studies appearing in peer reviewed journals are assumed to be reliable because of the good history of the journal. Let's try to ascertain the reliability of this source, looking at her history - and maybe we'll find some other things she discusses that we do know something about, so we can match up her worldview to ours.

And ... oh dear. Let's look at this blog, shall we? I'll ignore the warning sign of the 20+ links to "fat support" groups in the blogroll. Maybe she's just supportive of her large readers. Maybe she doesn't have an agenda? Benefit of the doubt and all that.

Oh, another long (LONG) article in which she completely demolishes another study, this time about the "obesity paradox" - being slightly overweight was associated with a slight increase in health. She claims that in fact the study shows that overweight and obese people are much healthier than the media reported, and they were covering it up.

Hm. She takes two major studies to pieces in as many posts. That's unusual, for not one but TWO studies to be completely wrong, in a short amount of time, and one person - her - to be the one to find where they are wrong. And both wrong, as it happens, in favour of eating.

Are you getting suspicious yet?

Let's move further down the first page of her blog. Ooh, a post in which she cherry picks a couple of bad examples of govt. health care to make an unsubtle point about the planned health reforms in America. Completely ignores that every other developed country has socialised health care and we do fine - plus live longer (which we shouldn't, since fat people have an advantage, apparently!).

I am beginning to smell a crank.

I make it down to "Pudge Police are coming (Part 2)" before calling it quits.

Still treating this article as something worth your time?

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