[flagged]
His brain worm had a bad experience with Kratom once
DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
71–80 of 199 posts
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#72Kratom has been beneficial for me. Extracts can go but the leaf should stay.
My opinion is that long term daily kratom use is terrible for your health, but it doesn't carry an overdose risk so it should stay legal and the decision to use or not should be up to the user.
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#73Ah yeah surely banning more substances will be the end of the problem this time! It definitely won't just push anyone who got hooked on this non-lethal opioid towards unregulated black markets filled with lethal fentanyl... Fun fact, this is one of two """temporary""" opioid schedulings happening right now. The DEA is also banning 5,6-Dichloro Desmethylchlorphine (SR-17018), which has minimal to no recreational value…
> It is hard for me to read the combination of these two bans as anything but active malice.
Reading the document...
> In recent years, online forum users have begun to discuss recreational use of these four synthetic opioids and commonly compared these four synthetic opioids to other traditionally abused opioids, such as morphine and fentanyl (schedule II substances). However, unlike these two drugs that have FDA-approval for use in specific medical treatments, the four synthetic opioids have no currently approved medical use and, based on positive identifications of these four substances in forensic drug exhibits and toxicology samples, are likely to be trafficked and abused similarly to other synthetic opioids, such as brorphine (schedule I).
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#74Earlier quoted context omitted.
You have to provide ID and be over 21 to purchase nicotine. You can't advertise nicotine products. You have to be licensed to sell nicotine products. Same for alcohol. Restrictions on who can buy, who can sell, and how you can advertise and market. These are not the same as some random pill from a gas station sold to anyone with cash with zero regulations, safety, restrictions, or even any requirement to tell you wha…
When I was a kid, there were cigarette vending machines. I am not that old.
Then what happened?
Better regulation, better enforcement, anti-smoking advertising campaigns, banning public smoking, and drastically reduced amongst youth and the general public.
Cigarette regulation to reduce smoking starting in the mid/late 90s is the poster child for public policy done well.
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#75Earlier quoted context omitted.
This was happening during the early 2000s, though in more "reputable" places (like nutrition and supplement stores; different "drugs" and chemicals, though). Not really surprised it is still going on in the weird little label producers.
You used to be able to find some wild stuff in GNC ~20 years ago, the 'pro-hormone' era was funny. All the cannabinoid analogs are a good example too, people just want to get high. I do miss salvia extracts though. Being able to pick that up in a head shop was nice before it got banned.
GNC used to sell freaking GHB in the 80s and early 90s!
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#76Earlier quoted context omitted.
So is caffeine.
And sugar
Sugar in moderation is a fine thing the issue the US has is more focused on how pervasive sweeteners have become in what looks like savory food. A ban would be a very silly thing but at some point America needs an FDA with teeth to actually crack down on labeling requirements.
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#77Kratom is such an interesting drug. About 10 years ago, when it was less well-known, you could find better raw leaf powder and it was helping people get off actual opiates. IIRC there's an effect where the actual chemicals get stronger for older leaves. The bigger market has caused the harvest period to shorten, making the powder worse quality, and creating room for the concentrated extracts and stuff like 7-Oh. Trag…
> People say "let doctors prescribe", but that ignores how in order for that to happen, a pharma company will need something they can patent, pay for the years of testing, get sole control over it for a period, and years later a generic can come about.
Is there not universies that could just do this research on the leaf itself?
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#78Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#79Anyone got a quick primer on what 7-Oh is? That's a new term for me and the web search doesn't seem reliable.
Kratom is a leaf that is primarily farmed in Asia which contains the active ingredient Mitragynine, which has some very mild partial-agonist opioid effects. When kratom is consumed, your liver converts a very small amount to a MUCH more potent molecule called 7-hydroxymitragynine. As with all natural drugs, some asshats in a lab decided to figure out how to create the latter molecule semi-synthetically and in bulk. They pressed them into pills and sell them in head shops and some gas stations. It's pretty addictive, nasty stuff.
Re: DEA to Temporarily Schedule 7-Oh and Related Substances to Protect Public Safety
#80Earlier quoted context omitted.
So is caffeine.
This is always mentioned when people talk about addictive substances being widespread. However, I think the key thing to think about isn't whether somethings addictive or not, but if said addiction comes with significant negative consequences/attributes. I don't think you'll find many people saying Caffeine is GOOD for you, but it just doesn't have significant negative outcomes like Tobacco.
There's lots of evidence for positive influences of Caffeine on the body (some negative as well), especially the brain. In particular, there's active and promising research on the neuroprotective effects for Alzheimer's [1] and Parkinson's [2].
"There is a wealth of accumulating biological, epidemiological and clinical evidence to support the further investigation of selective adenosine A2A antagonists, as well as caffeine, as promising candidate therapeutics to fill the unmet need for disease modification of PD."
1: https://www.mdpi.com/2218-273X/13/6/967 2: https://pubmed.ncbi.nlm.nih.gov/33349580/