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How to sequence your own DNA at home

bradleywoolf.com

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Re: How to sequence your own DNA at home

#61

Post by lukan »

shevy-java wrote: post #59
jdmoreira wrote: post #57

I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.

Many companies offer that. In the local area they have e. g. mail-like stations where you give out your order and they give you what you need (e. g. if it is a plasmid, it is mailed into storage boxes often on the same day or next day). "Not keeping it on their side" ... well. If they sequenced it, they have data in their computer, right? How could you avoid that? I don't see this as possible, it depends on trust (an…

"Not keeping it on their side" ... well. If they sequenced it, they have data in their computer, right? How could you avoid that? I don't see this as possible, it depends on trust"

First it depends on the contract, if it states they have the right, then they can and will legally use it.

If the contract would say no - then they would have a much harder time making use of that data, as it would be illegal.

Re: How to sequence your own DNA at home

#62

Post by stymaar »

jdmoreira wrote: post #57

I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.

> But I do want to sequence it using a third-party

Don't forget to change your DNA when the third party's database will eventually leak. (see the 21andMe's data leak: https://en.wikipedia.org/wiki/23andMe_data_leak)

Re: How to sequence your own DNA at home

#64

Post by rtodea »

bambax wrote: post #56

This feels like the acme of narcissism. How much time and money are people willing to spend on navel gazing?

When you are taking care of your health, and need to learn more about your built-in limitations is it still narcissistic?

At the bottom of the page there is a link to Sid Sijbrandij's cancer journey. He is one of the cofounders of GitLab. This is one of the coverages of his story: https://centuryofbio.com/p/sid

Re: How to sequence your own DNA at home

#65

Post by randogp »

__MatrixMan__ wrote: post #20

I've bee thinking about starting a company where I fish roots out of your sewer and identify the plant (by sequence if necessary) that you have to kill so your sewer doesn't collapse as soon as it otherwise would. $100 to stave off that $10000 sewer replacement for a few years would be worth it to a lot of people

How will you reach out to enough people so they are aware and can order the service? I'm thinking about the minimum viable business opportunity here.

Re: How to sequence your own DNA at home

#68

Post by inferniac »

jdmoreira wrote: post #57

I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.

I used Macromo, think theyre a czech company, they give you the data

Re: How to sequence your own DNA at home

#69

Post by Lvl999Noob »

eks391 wrote: post #37
cowthulhu wrote: post #34

Earlier quoted context omitted.

That’s a really clever idea, I would definitely pay for that in the right circumstances. Now that I think about it - could you just pour some sort of biodegradable broad-spectrum herbicide down the drain to get the same effect for cheaper?

This is precisely what I do each year with a product designed for this exact purpose. $8+shipping gets me enough for my annual pipe maintenance. It's even the special kind because I have clay pipes. I don't wasn't to kill parents idea. It's neat, and Im sure there's use cases that my solution doesn't meet

Isn't this a problematic idea? If you flush down herbicide without checking the results, you would risk breeding herbicide resistance in the weeds.

Re: How to sequence your own DNA at home

#70

Post by embedding-shape »

jdmoreira wrote: post #57

I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.

> I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend?

At one point I randomly bumped into a cancer researcher as he were in town for some conference. I posed exactly the same question to him, and he told me to reach out to local labs, specifically to the individuals posted on the websites, and ask them directly to help me out or point me in the right direction. He said he've done it himself in multiple countries before, but I'm not sure yet people helped him because of his title, but he assured me I'd find someone willing to help me even if I was just a lowly software engineer. I have yet to actually try it myself, but maybe you could try if there is any nearby? :)

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