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How to sequence your own DNA at home

bradleywoolf.com

11–20 of 161 posts

Re: How to sequence your own DNA at home

#11
This is so cool. Thanks for doing this. The fact that we have this in a palm sized object is just crazy. Also, if/when we have a similar sized device for doing CRISPR .... umm i should stop here - it's becoming the plot of Gattaca

Re: How to sequence your own DNA at home

#12
post #7

I am very impressed with the, why wait? just do it now approach to the future. which while not here, IS there.

Nothing about this is the future. Sequencing at home will not solve any major problems. It's mainly a fun exercise to demonstrate that sequencing has been commodified.

Re: How to sequence your own DNA at home

#15
post #8
post #4

https://www.the-odin.com/whole-genome-sequencing-30x/ If you want it quick and cheap(er) - 599.00

If it's an US-based lab, aren't they subject to CLIA with all its retention requirements? For $7.5k+ you get a guaranteed privacy (as other comments suggest, other properties may vary, but at least the data never leaves your home).

I suspect there is a deep sequencing service that is non CLIA and cheap. True. they may not be trustworthy with the data. That said, there are steps here where the data is put into Claude. Do we trust that ?

Re: How to sequence your own DNA at home

#16
post #15
post #8

Earlier quoted context omitted.

If it's an US-based lab, aren't they subject to CLIA with all its retention requirements? For $7.5k+ you get a guaranteed privacy (as other comments suggest, other properties may vary, but at least the data never leaves your home).

I suspect there is a deep sequencing service that is non CLIA and cheap. True. they may not be trustworthy with the data. That said, there are steps here where the data is put into Claude. Do we trust that ?

I would never trust that. Instead I would use Claude to teach me genomics and build the tools to process and interpret data locally

Re: How to sequence your own DNA at home

#17
> This is intended to be read by AI- please just copy and paste the URL of this and have ChatGPT walk you through it. If you have AR glasses, even better, since the AI can walk you through the whole protocol.

What kind of magic is going on here, am I missing something?

Re: How to sequence your own DNA at home

#18

> This is intended to be read by AI Fuck this

Man, doctors thought they had it bad before. For just a six yards I can play Peter Thiel at home! $6k invested so I can set an AI in YOLO mode to tell me I have some hyper-specific version of kennel cough?

“But that occurs in dogs?”

“You’re right. Let me look into actual gene sequencing instead of just guessing. I think the N is the load bearing letter.”

Re: How to sequence your own DNA at home

#20
I've bee thinking about starting a company where I fish roots out of your sewer and identify the plant (by sequence if necessary) that you have to kill so your sewer doesn't collapse as soon as it otherwise would.

$100 to stave off that $10000 sewer replacement for a few years would be worth it to a lot of people

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