Cannabis users face substantially higher risk of heart attack (2025)

> Since both studies were limited by their retrospective nature and the meta-analysis was limited by the challenges inherent in pooling data from multiple studies, researchers said that additional prospective studies would help to confirm the findings and determine which groups may face the highest risk.

Here's the thing that both the alarmists and the naysayers keep ignoring: all this data is new, it's recent, and decades of effective global prohibition have meant the only sources of reliable data came from either post-war/pre-prohibition studies (often by Defense Departments) or from "anecdata" gathered retrospectively among large cohorts. We still lack a substantial amount of direct, quality, long-term data on drug use and Nth-order impacts on the body, and these studies are the first steps towards getting more data from higher quality research to draw better conclusions from.

If anything, I try to be quite open with my Doctors about my own use precisely because I know that data is thin and dated, and any contributions from patients in an honest manner is going to help draw better conclusions for healthcare guidance tomorrow. Letting alarmists use these thin precursors as justification for a return to total prohibition is the wrong move.

Growing up I definitely knew some people who had their demons who turned to drugs.

However we also had a lot of people who were in good situations who picked up drugs for purely recreational reasons. One of my friends at the time even boasted that drugs were actually more appropriate for people like him who were educated, in good situations, and rational (his description of himself) because they knew how to manage themselves and their usage better. He even had links to some subset of the rationality community who had become pro-recreational drugs with a lot of justifications.

His turn to drug use marked the end of his promising academic career. He started struggling with mental health in ways that were obviously related to the drugs. Holding a job had never been a problem until he starting smoking, which marked his turn toward job struggles. His friends and family relationships started declining and falling apart.

He’s not the only one I know like this. The first person I knew who had to go to rehab for drug addiction was a happy, successful guy who started using drugs as a way to party more and for longer. He thought his life was awesome and he was invincible.

I think there’s become a belief that drug use is purely a symptom, but I’ve seen enough people go from happy to falling apart as an obvious result of the drug use. Most of the people I know who started using drugs didn’t do it at their homes in private to cope, they started doing it at parties with friends.

This is even well known with alcohol: There is common belief that being a “social drinker” is a different risk profile than someone who does their drinking alone.

I think it’s a comforting idea that we tell ourselves that nobody chooses to use drugs, they are driven to do so by circumstances out their control. We like removing blame from people and hoisting it on to the world. I don’t think it’s always true, though. Many people use drugs because drugs are rewarding (at first) and they like the way the drugs make them feel. The negative consequences come later.