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Global review confirms mRNA vaccines are safe, effective and full of promise

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Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#81

Post by cedws »

swingboy wrote: post #67

Serious question in good faith: what was the deal with the “calamari” (clots?) the anti-vax crowd kept talking about being found in the veins/arteries of folks who took the Covid vaccine?

IIRC the vaccines were provably linked to the death of young people who had blood clots they shouldn't have had.

The common argument made is that the vaccine saved more lives than they took, but this is pretty fucked up IMO. It's the trolley problem IRL - if you force someone to get a vaccine and they die as a result, you are responsible for their death. Also, the manufacturers can never be held responsible, because they have legal immunity for the COVID vaccines.

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#82

Post by Torn »

swingboy wrote: post #67

Serious question in good faith: what was the deal with the “calamari” (clots?) the anti-vax crowd kept talking about being found in the veins/arteries of folks who took the Covid vaccine?

> Now an international team, led by Flinders University, have found that in a small number of people, the immune system can accidentally confuse a normal adenovirus protein with a human blood protein termed platelet factor 4 (or PF4).

Seems to have been a legitimate, very rare, side effect

https://www.flinders.edu.au/research/articles/covid-vaccine-...

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#83

Post by d--b »

You mean the stuff the whole world got injected with in 2020? Good to know!

Seriously though, I am very pro-vax, but the fact that studies like these come out now is just confirmation that people had the right to doubt the safety of mRNA back then. Many people shamed others for being anti vax but everyone has the right to be careful.

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#84

Post by ggm »

epistasis wrote: post #38
linzhangrun wrote: post #34

Two most populous countries, China and India, seem to have mainly relied on inactivated vaccines.

Which makes sense as they had less access to new technologies, and scaling issues were very hard in the early days. But I'm not quite sure how that's relevant to the article...

Both economies have massive drug industries and China in particular has advanced manufacturing processes for decades. I suspect they made an economic/risk decision and will be reviewing it in the light of mRNA production lead time.

We're way beyond lysenko. China has no intellectual or political baggage in vaccine theory or bio engineering.

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#85

Post by ggm »

Shorter lead times in the face of viral mutations will be helpful.

Tailored vaccines for things like cancer are a game changer.

I live in hope of a semi-universal flu+related vaccine.

I live in fear of the measles induced "immune amnesia" effect.

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#86

Post by manwe150 »

epistasis wrote: post #49
alex1138 wrote: post #44

Earlier quoted context omitted.

[flagged]

[flagged]

Having read it, he does cite something for almost every claim. Although almost every source also contradicts his conclusions on some basic, logical, statistical, mathematical, or humane level, if you bother to fact check them. So it’s quite hard to quantify what it means to say it has good citations.

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#87

Post by ifyoubuildit »

yieldcrv wrote: post #56

> The researchers emphasize that, like all vaccines, mRNA vaccines can have side effects. They found that serious adverse events—such as myocarditis, which occurs more frequently in younger males—are rare and consistently outweighed by the vaccines’ protection reminder to the myocarditis-maxxies, the actual virus causes that too and the 2020-2021 variants caused it worse if we were all going to drop dead (I think 2 y…

> reminder to the myocarditis-maxxies, the actual virus causes that too and the 2020-2021 variants caused it worse

Do you know if the vaccine prevented the virus-induced myocarditis? Cause the vaccine didn't do much to stop people from getting covid, multiple times even.

So many people frame this as either/or, you either had the risk of covid induced myocarditis or you had the (supposed) lesser risk of myocarditis from the vaccine. But if you got the vaccine (x times) and then covid (y times), isn't your risk roughly x + y?

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#88

Post by tjohns »

Torn wrote: post #82
swingboy wrote: post #67

Serious question in good faith: what was the deal with the “calamari” (clots?) the anti-vax crowd kept talking about being found in the veins/arteries of folks who took the Covid vaccine?

> Now an international team, led by Flinders University, have found that in a small number of people, the immune system can accidentally confuse a normal adenovirus protein with a human blood protein termed platelet factor 4 (or PF4). Seems to have been a legitimate, very rare, side effect https://www.flinders.edu.au/research/articles/covid-vaccine-...

It's worth clarifying that the adenovirus-based (viral vector) vaccines that article is discussing were a completely different technology from the mRNA vaccines.

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#89

Post by quinnjh »

timr wrote: post #64
baronvonsp wrote: post #53

Earlier quoted context omitted.

Yeah that's called survivorship bias. The ones that make it to market can be wildly profitable to manufacture . Doing all the work to sift through what does and doesn't work to discover new vaccines wouldn't happen without public funding.

No, that’s called pharmaceutical development. That’s the business. We don’t generally fund Merck’s R&D with federal money. You’ll note the following critical detail from the article: > That will impact 22 projects being led by major pharmaceutical companies, including Pfizer and Moderna , for vaccines against bird flu and other viruses, HHS said. We’ve gone so far round the bend with partisanship that straight-up cor…

Certainly not _all_ of it, but a few billion at least.

for the curious:

https://www.usaspending.gov/search?hash=5ec35bf87ec1fd63d28d...

Re: Global review confirms mRNA vaccines are safe, effective and full of promise 

#90

Post by doginasuit »

alex1138 wrote: post #44
epistasis wrote: post #35

Earlier quoted context omitted.

[flagged]

[flagged]

Well cited doesn't mean very much outside of the context of peer reviewed work.

This book pushes Ivermectin and Hydroxychloroquine as "miracle cures", thanks to that idea my relatives also have a stockpile of both.

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