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What Ozempic does to the gut-brain axis

psychologytoday.com

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Re: What Ozempic does to the gut-brain axis

#491
post #23

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I got pancreatitis from Zepbound, but it was indirect. Turns out rapid weight loss can cause gallstones, especially if you're genetically predisposed to them. I had one that ended up stuck in the bile duct, causing acute pancreatitis. I had to get my gallbladder removed shortly after and hundreds of stones were found. I would consider getting an ultrasound since the stones don't just go away when you stop taking the…

Wouldn't that be cholecystitis (and a cholecystectomy), not pancreatitis?

If the stone blocks below the hepatopancreatic ampulla (the ampulla of Vater) then it will be blocking the pancreatic duct as well, leading to a buildup of digestive enzymes inside the pancreas.

Re: What Ozempic does to the gut-brain axis

#492

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Look up what percentage of people take statins long term at some point in their life. For people in certain age brackets it's more than the 40% of people taking GLP-1s that you are so concerned with. Why don't they just lower their cholesterol via other means? Look up what percentage of people take antidepressants. Why don't they just try being happy? Look up what percentage of people regularly take OTC pain killers,…

> Look up what percentage of people take antidepressants. Why don't they just try being happy? If there's a genuine chemical imbalance that needs correcting, whether that's causing obesity or depression it certainly warrants medical intervention. That should only account for a couple of % of people, however. If 40% of your population is on antidepressants, in other words 40% of your population is chronically depresse…

> What happens when 50% of the population is on some cocktail…

I dunno. What happened when 99% of the population got the polio and measles vaccines?

Re: What Ozempic does to the gut-brain axis

#493
post #344

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Sounds like they eat the wrong things. So learning to eat properly and stopping with GLP after a while sounds more reasonable to me. Also that's how my mum got it in the swiss test run. It was never supposed to be long term, just to help change eating habits.

If telling people to eat better fixed obesity, we wouldn't have an obesity epidemic.

I mean the idea is that GPT helps to reduce appetite while you learn to eat properly. Not to take GPT the rest of your life.

Re: What Ozempic does to the gut-brain axis

#494
post #404
post #344

Earlier quoted context omitted.

Sounds like they eat the wrong things. So learning to eat properly and stopping with GLP after a while sounds more reasonable to me. Also that's how my mum got it in the swiss test run. It was never supposed to be long term, just to help change eating habits.

Is this advice coming from personal experience of significant diabetes and weight reversal or just online reading informed opinion? Physiology & psychology are quite complex and individualized and "just do this.." doesn't quite work at any sustainable level when people have jobs, families, mortgage, sick children & sick parents to also manage at the same time.

I lost weight by changing my eating habits (which definitely wasn't easy but doable) and have family who used GPT with different results. So a little of both I guess.

I stand by my words that just using Ozembic without changing your habits on the way can't be the right way. And as far as I know studies suggest that that is actually the case. Like with any diet really

Re: What Ozempic does to the gut-brain axis

#495

Earlier quoted context omitted.

considering what we have been learning about the importance of a working gut brain axis I'd be highly worried about Ozempic harming this connection.

whatever we learned about gut brain axis dysfunctionality? I thought most of the biggest findings were in that it exists in the first place.

the term "gut feeling" exists for a reason. the findings substantiated this colloquial wisdom and its relevance ... the article hints at it by associating mental disorders with gut microbiome. I wouldn't be surprised at all if it turns out that Ozempic et al. harm this gut/brain cooperation ... I'd bet on it.

Re: What Ozempic does to the gut-brain axis

#496

Earlier quoted context omitted.

Why would exercise use help? Burning calories makes your body want to eat, obviously - this is how our bodies are supposed to work.

Exercise absolutely helps as it helps regulate blood sugar more effectively. A surprising effect of building muscle and exercising is that your body becomes more insulin sensitive and your blood sugar stabilizes instead of having drastic swings.

This is all true but it doesn’t change that when you increase your metabolic rate from increased activity you’re going to get hungrier.

Re: What Ozempic does to the gut-brain axis

#497
post #400

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Do you think going thru an allergy shot regime from an MD allergy Dr is a viable alternative to actually dealing with the undelying allegie(s)? Seems like the issue is unsettled last Inchecked

Do you mean "hypo-sensitization" aka "allergen immunotherapy"? I tried that too but couldn't really tell whether it worked either. My experience was about antihistamines, which are definitely effective.

But how long was your regime before you turned back to antihs?

My impression was it was weekly at first for 1-few months then monthly for like 5 years.

Wish i had started like yestercade :(

Re: What Ozempic does to the gut-brain axis

#498

Earlier quoted context omitted.

Not really the fiber and stuff is normally too filling

Some fibers are not very filling, they just go through the guys quickly and you are hungry again a couple of hours later.

name the fibers, the meal and the quantity

if you one broccoli head with one pound of icecream then sure, you will feel hungry again quite soon

Re: What Ozempic does to the gut-brain axis

#500

Earlier quoted context omitted.

To the others on this reply, I take 1/4 dose of the "clinical dose" and it has been life changing. I've lost 30 lbs. I've done that in the past, but for me that was harder than ranger school in the army. I LOVE food. Eating out and family dinner were always important to me. I was very worried that I would lose my pleasure in this. I haven't. But now I can just eat 1/2 slice of pie. Or 1 scoop of ice cream, etc etc. I…

I've been on Mounjaro for a couple of years. Unfortunately this effect seems to plateau somewhat and you have to bump your dose. I've changed doses 3 times now, so I'm pretty familiar with how long each increase lasts. It still provides some appetite control, but those initial gains, or the honeymoon phase, definitely tapers. Still, I'm better off being on it versus not and I think it allows me to maintain a healthy…

Which was it? Did it plateau or taper?

With same dose do you get flat and consistently low appetite or do the effects lose power if you dont up the dose?

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