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What Ozempic does to the gut-brain axis

psychologytoday.com

471–480 of 555 posts

Re: What Ozempic does to the gut-brain axis

#471
post #265

Earlier quoted context omitted.

People can get fat by eating too much healthy food.

Not really the fiber and stuff is normally too filling

Some fibers are not very filling, they just go through the guys quickly and you are hungry again a couple of hours later.

Re: What Ozempic does to the gut-brain axis

#472
post #265

Earlier quoted context omitted.

People can get fat by eating too much healthy food.

I consumed +11lbs (5.1kg) of food yesterday for only 2,500kcal If you have a stomach and appetite that are capable of consuming the 15 to 20 lb you need to eat 3,500 to 4,000 calories of similar foods, you ought to call a research lab

Nuts are healthy to eat, its easy to eat 4000 calories of nuts. Healthy doesn't mean low calories.

Re: What Ozempic does to the gut-brain axis

#473
post #363

Earlier quoted context omitted.

The latest fad promoted by companies to sell you something?

Eating disorders are mental health condition. Just because there are a lot of visible "false" cases, it doesn't mean that someone else is not living it for real. Your comment is insensitive

these types of (modern) eating disorders are a product of our current market, and I think that blaming humans for eating wrong due to 'food noise' when many shelves have little else to offer is insensitive victim blaming.

the perpetrators are the people selling poison under false auspices.

we're not blaming people with pica for eating drywall.

We're blaming profiteers for shoveling garbage into the mouth of anyone with a buck while systematically lobbying to maximize garbage advertising and minimize actual food where feasible and simultaneously incentivizing sales groups as much as is profitable -- all the while trying to convince medical professionals and scientists to produce overtly narrow results to support the public consumption through bogus 'science' papers.

Re: What Ozempic does to the gut-brain axis

#475
post #335

Earlier quoted context omitted.

Because usually you can't study long-term effects before releasing a drug, and even then it can take a long time for them to surface. I took antihistamines basically throughout my 20s. My allergy specialist said there's no reason not to. I developed some other issues and wanted to stop taking antihistamines to see if that would help (or get a hint whether they were causing it) - but that got me into itching hell for…

Do you think going thru an allergy shot regime from an MD allergy Dr is a viable alternative to actually dealing with the undelying allegie(s)? Seems like the issue is unsettled last Inchecked

Allergy immunotherapy (shots) work by gradually desensitizing the immune system for your specific allergens over several years, so yes. Some people can get to the point where they no longer need a daily antihistamine, but it's all very personalized and individual.

In any case, it's worth doing the skin prick allergy shot testing so you can have some idea of what common allergens affect you and the intensity of each.

Re: What Ozempic does to the gut-brain axis

#476
post #21

Earlier quoted context omitted.

Why not? People take depression meds, blood pressure meds, all kinds of meds for their whole life. I'll be on omeprazole for reflux my whole life. It doesn't solve the underlying problem of my gut being prone to overpumping acid into my stomach. So omeprazole is problematic? The underlying issue is being treated, it's treated by taking the drug. It works. It's doing its job. I'd be curious as to how you came to this…

> People take depression meds, blood pressure meds, all kinds of meds for their whole life. And a lot of these medications have side effects that can affect quality of life negatively in other ways. That doesn't mean they're not helpful, or shouldn't be taken. But the "no free lunch" rule usually applies, sometimes to a noticeable degree.

OK, so is the point being made that "drugs have side effects"?

Wow. I had no idea.

Come on, why is it that whenever GLP-1s come up on this site, the comments are filled with people helpfully pointing out this fact as if no one knows it already?

Re: What Ozempic does to the gut-brain axis

#477

Earlier quoted context omitted.

>my body and mind are no longer is in starvation mode What does it mean? If a drug reduces your desire to eat food, wouldn't it also decrease your desire to eat food beneficial for your body? I think the effect most people want is to stop craving junk food but still eat nutritious food required for muscle growth and health.

It does which is why medically supervised weight loss with GLP1s includes diet recommendations to mitigate this. But in my experience, decreased cravings make it easier to choose food rationally. The food noise that causes people to overeat usually doesn’t cause them to overeat healthy foods anyway.

> But in my experience, decreased cravings make it easier to choose food rationally. The food noise that causes people to overeat usually doesn’t cause them to overeat healthy foods anyway.

"Food noise" is much more than just craving calories, we have cravings for most of the different nutrients we need. That is how people ate a balanced diet in history even though it was much harder to do back then, peasants craved meat and vegetables even though it was easier to just eat potatoes for calories.

Re: What Ozempic does to the gut-brain axis

#478
post #21

Earlier quoted context omitted.

Why not? People take depression meds, blood pressure meds, all kinds of meds for their whole life. I'll be on omeprazole for reflux my whole life. It doesn't solve the underlying problem of my gut being prone to overpumping acid into my stomach. So omeprazole is problematic? The underlying issue is being treated, it's treated by taking the drug. It works. It's doing its job. I'd be curious as to how you came to this…

If you can find a way to use your own free will and self-discipline to stop the bad condition then that seems preferable to using a drug. Maybe someone doesn't have the willpower in which case it's good that we have the drug. With regards to omeprazole, I changed my diet a bit and no longer needed the omeprazole. I don't know exactly what it was, but if you can get off of a drug because you don't need it anymore that…

> Maybe someone doesn't have the willpower in which case it's good that we have the drug.

This is all that needs to be said and this is also not that profound of a point. It's literally just harm reduction.

Why do people have such a problem with harm reduction? Why do they feel the need to feel oh-so-smart and point out "weeellll acccktschually there is still some harm so its better if you didn't need the harm reduction therapy and instead just i dunno magically not require it"

Re: What Ozempic does to the gut-brain axis

#479
post #150

Earlier quoted context omitted.

No, the symptom is being treated, not the underlying issue. And that's ok, but treating the underlying issue, when possible, is better, as the problem ceases to exist.

And what's the underlying issue, exactly?

Eating ultra processed foods with added sugar / loads of calories. A huge reason why they're so destructive is because they lack fibre (which keep our microbiomes healthy) and lack compounds which are good for us. Try keeping weight on while eating minimally-processed food that is more vegan in nature: the amount you'll have to consume to keep the weight on is significant. When you start this diet, you won't like it that much and you will feel hungry since your microbiome is used to your old diet -- but try doing it for a month, and you'll see a huge shift in the way you feel and the foods which you crave (the above will start transforming your microbiome quite significantly). Do it for 3 - 6 months you'll wonder how in the world you ever lived without it.

Re: What Ozempic does to the gut-brain axis

#480
post #427

Earlier quoted context omitted.

But the drug feeds the flora in your gut, which tells your brain to crave more of it. Like if you completely cut off sugary foods for 2-4 weeks you won't crave them as much. Why? The gut flora that feeds off sugar specifically dies off and can't send as strong signals to your brain. Thus: gut-brain axis. It's a thing and will become more important when we study it more. Your brain isn't as much in control as you thin…

Your explanation doesn't seem plausible to me. If your stomach and small intestine is working properly, the bulk of the bacteria shouldn't see much sugar. Afaik the mechanisms how the intestines regulate the gut flora are not well understood. At least not to the point where there are any working treatment for the many widespread digestive problems. There is some slow progress around fecal transplant research.

There's a bunch of "in mice" research on it, but with actual humans it's really hard because we don't yet have the tools to measure the baseline composition of gut bacteria before and after the experiment.

It's all mostly just anecdotal and empirical.

Same with the fecal transplant stuff, which (AFAIK) basically replaces one persons gut biome with a different one. Which causes cravings to change completely for the recipient, in some cases resulting in weight loss.

Which, to me, kinda tells that it's not a willpower or brain thing, it's just the gut biome controlling what you "want" to eat.

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