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Anti-aging injection regrows knee cartilage and prevents arthritis

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Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#91

Post by [deleted] »

mancerayder wrote: post #78
mcswell wrote: post #73

Anecdote for any runners reading this: I'm a 75 year old runner. (Some young runners might say I run at a jogger's pace, I just tell them to keep off my lawn.) A couple decades ago, I stopped running on concrete or asphalt, and took up trail running, i.e. running on (mostly) dirt. It feels way easier than running on asphalt, much less on concrete. If you're skeptical that running on concrete or asphalt feels harder,…

I'd worry about sprained ankles on a false step or a slippery leaf-rock trap. Is there a technical approach to running in these conditions?

[deleted]

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#92

Post by abrookewood »

nappy-doo wrote: post #3

As I've gotten older, my knees have been the main signal letting me know. I tore my meniscus years ago. This is exciting news for people like me.

I've torn mine as well and am yet to get it repaired. Did you get surgery? Anything working for you?

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#93

Post by nosefurhairdo »

mettamage wrote: post #24

Does anyone have any idea if you have arthritis what you can do to manage the symptoms? I figure there are some people here that researched it relatively well.

Arthritis is a general term; need narrow down for useful advice on managing symptoms.

Two most common types are osteoarthritis (wear-and-tear associated with aging and/or injuries) and rheumatoid arthritis (autoimmune).

I only know about age-related knee osteoarthritis to try to help my mom manage her symptoms, so I'll share my understanding of treating that.

High ROI, low cost: - weight management. Extra lbs are extra stress on the knees, plus I suspect chronic inflammation associated with being overweight can exacerbate arthritis independent of mechanical stress. - exercise, specifically low impact cardio and any pain-free strength/hypertrophy work targeting the musculature around the knees (mainly quads).

Variable ROI, low cost: - NSAIDs, specifically topical to focus on treatment area and reduce impact on GI system/kidneys. - curcumin, mixed evidence but some people report benefits.

Variable ROI, high cost: - PRP injections. Apparently the quality on these varies dramatically by provider. Would recommend doing research and comparing multiple providers if possible. - Knee replacement. Far from a panacea; you'll lose range of motion forever, plus plenty of other trade-offs. Most people recommend putting this off for as long as possible.

Also interesting is low dose radiation treatment for knee OA. More affordable than other procedures and has some promising research.

Not much else on the novel treatment front that I've found. Curious if anyone thinks I've missed anything worthwhile.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#94

Post by FpUser »

cake-rusk wrote: post #89
mcswell wrote: post #73

Anecdote for any runners reading this: I'm a 75 year old runner. (Some young runners might say I run at a jogger's pace, I just tell them to keep off my lawn.) A couple decades ago, I stopped running on concrete or asphalt, and took up trail running, i.e. running on (mostly) dirt. It feels way easier than running on asphalt, much less on concrete. If you're skeptical that running on concrete or asphalt feels harder,…

Why not take up cycling?

>"Why not take up cycling?"

I was a cycling maniac for some time. It fucks one up (knees, back, elbows) anyways. After 10 years of that I cut it down to occasional pleasure rides. Luckily all my pains had stopped after a couple of years.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#95

Post by chrisfosterelli »

IsTom wrote: post #56
chrisfosterelli wrote: post #38

Earlier quoted context omitted.

Among endurance athletes collagen supplements have become increasingly popular the past couple years -- from what I understand the evidence is kind of mixed though e.g. https://thefeed.com/products/pillar-performance-collagen-1?v...

I don't get what's the supposed mechanism of action here. Collagen is a hard to digest protein and it has to get digested to be processed and then it's no longer collagen. Why not just eat any other protein source instead?

Yes, that seems to sort of be the criticism and mixed results. Although not everyone has a complete protein diet so theoretically although it breaks down the idea is you then have all the things you need, should your body choose to use it to build collagen.

But I agree, I'd rather start solving deficiencies at the diet level than the supplement level and haven't integrated collagen personally so far.

TBH I suspect marketing plays a big role. "Collagen = good, therefore just buy it and eat it" makes logical sense if you don't actually do any research first.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#96

Post by davkan »

mancerayder wrote: post #78
mcswell wrote: post #73

Anecdote for any runners reading this: I'm a 75 year old runner. (Some young runners might say I run at a jogger's pace, I just tell them to keep off my lawn.) A couple decades ago, I stopped running on concrete or asphalt, and took up trail running, i.e. running on (mostly) dirt. It feels way easier than running on asphalt, much less on concrete. If you're skeptical that running on concrete or asphalt feels harder,…

I'd worry about sprained ankles on a false step or a slippery leaf-rock trap. Is there a technical approach to running in these conditions?

You just get used to trail running over time. If you’re nimble and light on your feet a slip almost never turns into a fall. With practice you dodge the bad steps without much thought or you step knowing it’s iffy, slide and keep running. You don’t commit hard down on your heel.

The form i use basically the “natural” running style. Land with your body over your foot, land on your foot flat or on the ball. This is good for trail running because it’s much easier to not commit to a step when you’re not planting hard with your heel.

I’ve never sprained an ankle trail running, not that it can’t happen. I’ve gone like 90 degrees on my ankle before but I can usually unweight and collapse on that leg and catch myself on the other leg and keep running. I run in sandals and I backpack in trail runners.

Trail running strengthens your ankles what with all the uneven ground that has to be compensated for.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#98

Post by 8f2ab37a-ed6c »

yep31 wrote: post #83
8f2ab37a-ed6c wrote: post #76

Earlier quoted context omitted.

Yep. On a keyboard with 8 thumb cluster keys per side, and custom 35g switches to lower the force needed to actuate, that helped a lot, but still not enough to be pain-free. Unfortunately once the damage is done on certain joints you can only do so much short of not using those fingers at all. 30 years of hammering keys pretty hard eventually catch up to you.

You should try 20g springs, they are really good for typing. I also removed the keycaps and replaced them with small pieces of band-aid on top of the switch stems which also helped. Also dictating plain text like comments and typing only for correcting errors in dictation and for short actions is better. It's easier to press a button rather than say a lengthy command, because vocal cords can also be damaged by speaki…

Where have you been able to find ultralight springs available to consumers? I was looking into this last week and the 10-20g ones were only available straight from the factory in South Korea with shipping costing $200... I was happy to get them and swap them out, but that shipping pricetag was too much of a highway robbery.

Would appreciate any advice here :)

And, intrigued about the idea of not using key switches at all. Are there any aftermarket alternatives available online for "keycaps" that are better at softening the impact on the finger, something softer and bouncier perhaps? Seems like something people would have experimented with.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#99

Post by rjdj377dhabsn »

stacktrust wrote: post #9

> Osteoarthritis occurs when a joint is stressed by aging, injury or obesity. The chondrocytes begin to release pro-inflammatory molecules and to break down collagen, which is the primary structural protein of cartilage. When collagen is lost, the cartilage thins and softens; the accompanying inflammation causes the joint swelling and pain that are hallmarks of the disease. Collagen synthesis in the human body can be…

A recent meta analysis suggests the positive results for collagen are mostly funding bias. See discussion here:

https://massresearchreview.com/2025/09/29/connecting-the-dot...

I have been taking collagen, but will likely stop.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#100

Post by giardini »

aeonik wrote: post #70
leechy wrote: post #66

Turns out the pain in my knee was a latent infection with staph aureus, forming small nubs under the skin. Debrided the skin, removing the nubs, applied 3% doyiciclin creme and pain is gone. This for a knee with 2 operations before and teo doctors saying I need a replacement. Doctors are mostly unhelpful idiots imho.

Yea, same here, following the studies had helped me fix a 18 year old shoulder tendon issue. I owe that research group a lot.

What happened to you? Might anything you have learned help me? Recommended reading?

I too have a shoulder tendon issue: 14 months ago a loud one-time "pop" occurred while doing a simple external rotation shoulder exercise with very light weight. I immediately lost most strength lhs and the shoulder felt very loose. More than a year later + 1 steroid shot my shoulder is much better but still loose.

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