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From your link "Kratom contains over 50 alkaloids—primarily mitragynine and 7-hydroxymitragynine—which act as partial agonists at μ-opioid receptors"
Cheese acts on opioid receptors also... we wouldn't call it an opioid
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They give me massive anxiety.
Well then I hope the 111th non opioid painkiller works for you. I know people in chronic pain (my body isn’t exactly a picnic) and so far none of them have gotten hooked on oxy but it’s always looming.
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A rheumatologist explained to me that in people with chronic pain from things like arthritis, the brain's pain perception can become permanently altered to register pain that no longer "exists". She explained that the brain itself is really the source of the sensation of pain, and you don't necessarily need a "real" source producing a signal. So one should at least not ignore pain if one can avoid it.
My late wife took her own life because of Chronic Pain. She was told "The pain has become fixed in your perception". Many years later we found that the actual cause was a Cerebrospinal Fluid (CSF) Leak. After two failed surgeries to fix it, she had enough and checked herself out. See our documentary Pain Warriors for the whole saga.
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wow I'm envious. I remember how much pimples hurt and I was astounded nobody warned me. This now makes me curious what the low pain tolerance to anxiety correlation is.
That the medical community acts as if you and I should be treated the same is insane to me.
In physiotherapy, we used to think that structural issues like slipped disks caused pain, but when we started imaging healthy people, we found the same structural issues commonly in the 'healthy' population.
Both how much pain we feel and how sensitive we are to it are things that can be learned. The bullet ant initiation rites of the Sateré-Mawé people are an extreme example.
A decent book on this is 'dopamine nation'.