Delighted to discover this kind of breakthrough is based on a gnarly regular expression: https://github.com/Svensson-Lab/pro-hormone-predictor/blob/m...
Beautiful yet terrifying. I'm glad that regex isn't something I'll ever have to touch.
Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
21–30 of 394 posts
Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#22What does "naturally occurring" mean in this context?
> Svensson has co-founded a company to launch clinical trials of the molecule in humans in the near future. At least not so natural that just 'anybody' can put it in a bottle.
Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#23Earlier quoted context omitted.
The article refers to results in animals which means it is probably years - maybe a decade - from being approved. Novo’s patent protection expires in 2033 [0] so it could be that the market is not yet worried about a potential competitor that likely won’t get to market before the IP protection runs out. [0]: https://www.reddie.co.uk/2024/08/30/the-year-of-ozempic-an-i...
And Novo (like many others) is already working on next-generation GLPs that’ll have new patent protection before Ozempic’s ends.
Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#24Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#25What does "naturally occurring" mean in this context?
Most people think "natural" means they can just go into backyard, dig up some root, and get this for free. But its " Gila Monster’s venom". So natural, but you aren't going to just go out and eat it like resveratrol from wine. At this point, 'natural', just means made from atoms, yes atoms are naturally occurring.
Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#26Isn't the molecule in Ozempic naturally occurring too?
Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#27Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#28They mention AI used to weed out molecules but don't mention how it was used. I'd be interested in know did they use pre-trained models or train one from the ground up.
For another example, and it actually calls out the name of the program.
Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#29Re: Natural occurring molecule rivals Ozempic in weight loss, sidesteps side effects
#30Earlier quoted context omitted.
> Svensson has co-founded a company to launch clinical trials of the molecule in humans in the near future. At least not so natural that just 'anybody' can put it in a bottle.
I think this is not really a charitable take. For one, nearly everything medical needs certain purity and concentration so you need specialized equipment. For two, even if a chemical is easy to produce by industrial standards, you still need to run trials to prove that it's both safe and actually does what you hope it does.
Could they have chosen to bring it to market as a supplement?