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Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

nature.com

181–190 of 236 posts

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#181

Earlier quoted context omitted.

Sometimes the first time you try something the new experience can be overwhelming. You can focus on a specific part of an experience, for example the bitterness of a drink and quickly decide you don't like it. It can also be that the first time you try something you are in a bad mood or negatively predisposed towards something, eg. your parents may have said something tastes bad while growing up and you haven't tried…

I’m specifically talking about taste and not experiences in general. I don’t like the taste of something I don’t try it again. I haven’t found it limiting and as I said I don’t understand people drinking coffee enough to acquire a taste for it. I know people do this and they end up liking coffee. I just don’t understand that mentality though. It’s not for me but clearly is for some people.

I used to be this way, but then I realized two flawed assumptions. Both related to each other:

1. Some % of the time, my first experience will not be like the others.

2. I will not be the same person the next time I try something.

If your strategy works for you and you don't feel limited, that's great! Many people do feel limited if they only ate things they liked the first time. I am very happy that I eat bell peppers, onions, yoghurt, coffee, and (less happy due to calories) beer. If I only ate what I liked when I first tried it as a kid, I would be eating a lot of cheese pizza, candy, soda, and ice cream.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#182
post #143

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

I agree with you about the experience, but nobody who really likes coffee goes to Starbuck for the taste:-). They are really addicted

You do have a point there.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#183

Earlier quoted context omitted.

I’m curious, what do amphetamines feel like to you that makes them addictive? For several months I took (extended release) dextroamphetamine and later lisdexamfetamine, because I was having a mental health crisis from a lifelong ignorance of ADHD(inattentive type), autism, and what was probably some sort of covid induced severe depression. This was in addition to Wellbutrin. While I’ve not found them useful in regard…

When I take them, anything I do feels insanely gratifying. Its just euphoric. Like as soon as they kick in I feel like im on a big drop on a rollercoaster. It goes away quick though, and gets replaced by a cadre of horrible side effects, which makes me just want more. They also make my mind race with ideas which excites me. They are never good and never go anywhere but the racing thoughts are thrilling. Honestly cant…

No that explains it really well, thank you. While that exact sort of experience is alien to me (my capacity for happiness or excitement is generally very muted), thanks to analogous enough experiences I can definitely see how that could become uncontrollable if people have them at hand.

If someone gave me 2 pounds of gummi bears that were secretly caffeinated, I could see doing something similar to myself.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#184
post #129

Caffeine does nothing for me at all, I do not get a kick when I drink coffee. It does not affect my sleep, it does not give me a boost at all. So I am a bit of jealous of those who can utilize caffeine for mental boost, I just drink it for the taste.

I used to say the same thing until I tried different types of coffee and different amounts. The average expresso doesn't do much. Also if you are already feeling well, it's unlikely you will feel a big difference unless you consume a high dosage of caffeine, which can also cause you some anxiety. Caffeine is great when we are feeling low energy or sleepy.

What specifically do you recommend trying? I don’t seem to get any physical symptoms after a coffee but my wife is the complete opposite.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#185

I've sad it before, and I'll say it again: the human body is not meant to ingest any other liquid than pure, filtered water.

Maybe you should stop saying it? When we are born we 1) don’t have a filter installed and 2) drink milk.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#186
post #30

I love my caffeine. But caffeine is an addictive, highly profitable substance. So advertising it and trying to promote it as somehow having real health benefits is widespread. I would not be surprised if routine consumption of caffeine was at least mildly detrimental to health. I think some drugs have managed to gain a special place in our society . Advertising and lobbying warps our perception of these drugs. I even…

This really hit home when I started swapping caffeine out for Adderall on work days. Literal amphetamines have a more mild effect on me than a strong coffee.

I agree, reasonable amphetamine dose is easier on me than too much tea and coffee.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#187
post #143

Earlier quoted context omitted.

> caffeine addicts are standing in line at Starbucks Have you considered that those people queuing outside Starbucks might be drinking coffee because they enjoy the whole experience? Caffeine pills are an absurdity to me because I only drink coffee for the taste. Why suffer the unwanted effects of a drug without the enjoyment that it’s supposed to come with?

I agree with you about the experience, but nobody who really likes coffee goes to Starbuck for the taste:-). They are really addicted

Starbucks is only a little worse than boutique coffee shops in my experience, but they are fast, conveniently located, open earlier, open later, pay their employees well (for a coffee shop) and pay for their employees' educations.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#188

Earlier quoted context omitted.

Everybody is different. 3 years ago I took a summer and then autumn off of caffeine; my intent was to quit and only use caffeine in "times of need". This would be an on-brand thing for me to do as a person, and something I wanted pretty bad. But after 4 full months without touching any caffeine, my mood/energy levels never returned or even really rebounded any further than they did after the first month. I'm just a d…

Possessing the GG variant of COMT rs4680 gene might explain this. Conversely, AA types might get overstimulated and irritable.

This makes me so tempted to get one of those whole genome tests. I had issues with anxiety from age 20 to 38. I was a regular drinker of coffee between the age 20 to 38. About a month after quitting I was finally able to yawn properly like I remember I was able to when I was young. Coffee overstimulates me I figure.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#189
post #30

I love my caffeine. But caffeine is an addictive, highly profitable substance. So advertising it and trying to promote it as somehow having real health benefits is widespread. I would not be surprised if routine consumption of caffeine was at least mildly detrimental to health. I think some drugs have managed to gain a special place in our society . Advertising and lobbying warps our perception of these drugs. I even…

> highly profitable substance Yes and no. I've been a fan of caffeine pills for years. They are very cheap, readily available (portable), and most importantly to me offer completely consistent dosing. With caffeine pills I'm able to ensure I stay below the FDA recommended maximum daily intake of 400 mg (worst case). Another fun bonus - when a physician asks you what your caffeine intake is and you respond in milligra…

>If you were taking any other drug (over the counter or RX) would anyone tolerate "today it's 100 mg, tomorrow it's 400 mg"?

afaik melatonin. Not super happy about it but it is what it is, giving it up has a high cost too.

Re: Caffeine suppresses cerebral grey matter responses to chronic sleep restriction

#190

Earlier quoted context omitted.

Unfortunately, there is almost nowhere on earth where a Hunter-gatherer can survive any more. The few remaining have been pushed to the very edge of survival by agriculturalists taking all the best land.

When I understood this is when I formally became an anarchist. Before grasping that, I didn't realize that I really didn't have a choice, no matter what. You serve or you die. Those are the options.

That is absolutely true. And the reason is that if you did have a choice, the system would crumble quite easily since those that find the system intolerable would then have somewhere to go and start something new or just live.
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