Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

High coffee consumption, brain volume and risk of dementia and stroke

tandfonline.com

Post reply on HN
Print view View original

101–110 of 142 posts

Re: High coffee consumption, brain volume and risk of dementia and stroke

#101

Post by elzbardico »

Kirby64 wrote: post #17
owlstuffing wrote: post #4

> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.

The scientific definition of a 'cup' of coffee is important. Usually this is defined as 4 ounces of brewed coffee, which means a normal mug of coffee (which can fit something like 10 oz) would be 2.5 cups! So, for most people's definition of a 'cup' of coffee, they really only mean 2.5 'mugs' of coffee.

Americans drink very watered coffee though compared to most of the rest of the world. For us that came from abroad, it is basically tea.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#102

Post by yanellena »

datavirtue wrote: post #72
Uinchuling wrote: post #57

Earlier quoted context omitted.

I doubt I'm the only obnoxious country dude who rolls into Starbucks and orders a "large". You can ignore their pretentious names, they're very accommodating.

Too insecure to use the size names. That's how it plays...fyi

It's probably more that you don't want a corporation to dictate how you describe (brand) the sizes of a drink where we have near universal language for that purpose already.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#103

Post by TyrianPurple »

owlstuffing wrote: post #4

> consumption of >6 cups/day was associated with 53% higher odds of dementia compared to consumption of 1–2 cups/day (fully adjusted OR 1.53, 95% CI 1.28, 1.83) 6+ cups! That’s a cranial marinade.

Coffee & Tea are both stimulants. So I wouldn't be wrong by coming to the same conclusion about tea drinkers. Guess my cranium has been marinated real good.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#104

Post by Arch-TK »

So my habit of putting in a lot of effort to prepare 1 or 2 cups of coffee per day puts me at the local minima for risk of dementia and stroke?

Excellent.

Now, while gloating about how this study matches up with my own biases, I would like to take a moment to remind everyone:

This is a single study, ignore it, wait for a meta analysis and then ask your local expert in that specific field to interpret it for you. Or, better yet, wait for a book covering a number of meta-analyses.

Single studies are not helpful for general consumption!!!

Re: High coffee consumption, brain volume and risk of dementia and stroke

#105

Post by benjijay »

Arch-TK wrote: post #104

So my habit of putting in a lot of effort to prepare 1 or 2 cups of coffee per day puts me at the local minima for risk of dementia and stroke? Excellent. Now, while gloating about how this study matches up with my own biases, I would like to take a moment to remind everyone: This is a single study, ignore it, wait for a meta analysis and then ask your local expert in that specific field to interpret it for you. Or,…

Should I consume 1-2 meta-analyses per day, and is there any risk associated if that number increases to 5+?

Re: High coffee consumption, brain volume and risk of dementia and stroke

#106

Post by morsch »

d1sxeyes wrote: post #90
stubish wrote: post #84

Earlier quoted context omitted.

It will average out, so we will need to ask a British person what size an average cup of coffee is.

Brit here, an average cup of coffee would be around 1 heaped tsp of instant coffee in a 300ml mug with a bit of breathing room, say 275ml? But that would include the milk, so maybe around 200ml water and 75ml of milk. Would vary quite a lot from person to person though.

That'd be around 57 mg caffeine. On the weak side, compared to espresso or drip coffee. You think the most common preparation is instant coffee? Kind of surprising.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#107

Post by zaphar »

chombier wrote: post #95
Kirby64 wrote: post #54

Earlier quoted context omitted.

Prep method matters so much though. For comparison, a standard double shot of espresso is typically 18g of coffee. This would yield approximately 110mg of caffeine. By comparison, the same 18g brewed using a pour over method should yield an 8oz cup of coffee with … likely around 170mg of caffeine. Check out this James Hoffmann video specifically on this topic: https://youtube.com/watch?v=etnMr8oUSDo

I remember reading somewhere that the amount of caffeine in the cup is also proportional to the brewing time, therefore an espresso may not actually contain that much caffeine in the end (for the same initial amount of ground coffee, of course)

When I was in Organic Chemistry in College we demonstrated this experimentally. A cup of drip coffee had more caffeine than a shot of espresso. We were college kids so I'm not sure how consistent our how methodology was but the result was pretty consistent across all of us.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#108

Post by op00to »

b800h wrote: post #88
xcv123 wrote: post #21

Earlier quoted context omitted.

The gene is called CYP1A2 with two variants. One variant is a rapid caffeine metabolizer. The other is a slow caffeine metabolizer. https://www.geneticlifehacks.com/liver-detox-genes-cyp1a2/ I have the rapid variant but could not sleep well on 6 cups.

Slow metaboliser here. If I drink a coffee at 11am my heart rate rises and doesn't return to normal until the following morning. There are other genes for it too, like one that affects the degree to which coffee causes anxiety. And plenty of others that we haven't found, presumably.

I love love love love coffee. It took me years to realize that my high blood pressure was controlled almost immediately by cutting out a high-test canned “Draft Latte” drink. I can drink a single 8oz cup every few days. Decaf is fine.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#109

Post by op00to »

FirmwareBurner wrote: post #18
op00to wrote: post #9

Earlier quoted context omitted.

That’s like a little more than 2 venti Starbucks.

> more than 2 venti Americans will do anything to not use the metric system :)

Haha! I was just thinking that I see people drink like 3-4 of those huge coffees a day. I am a true American Metric Patriot.

Re: High coffee consumption, brain volume and risk of dementia and stroke

#110

Post by op00to »

Uinchuling wrote: post #57
zdragnar wrote: post #37

Earlier quoted context omitted.

Venti is the Starbucks name for their largest size cup, which holds 20 ounces. Most people don't really care about the exact, specific volume of fluid, they just go by whatever the cup size happens to be called. At least it is more descriptive than the grande or short cups, or the small / medium / large at other places (even if you have to know that venti is 20 in Italian to make the connection).

I doubt I'm the only obnoxious country dude who rolls into Starbucks and orders a "large". You can ignore their pretentious names, they're very accommodating.

I order from the app, I think both the barista and I prefer to reduce talking. :)
Post reply on HN