101–110 of 258 posts
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mRNA will eventually save the day for everyone, including for perfectly healthy individuals, but to me as a healthy 40yo person, with no known immunity issues, not overweight etc. etc. it is in my opinion still too risky to take just like that. It's an interesting take. From what we know so far, the risk from taking vaccine is much smaller than from covid infection. You might counter this with highlighting the "so fa…
Should this really be called a “vaccine”? I feel like that is going to give people the wrong impression about what it does. I think labelling it gene therapy, immune therapy, or something like that would be closer to what it actually does. Also really interested to see if people will need and/or benefit from periodic re-treatment. I guess they can figure that part out if it makes it to market.
It's using the same mechanism as vaccines (exposure to the proteins in question), it's utterly bizarre to conflate it with gene therapy.
It's probably reasonable to call it a vaccine based immunotherapy.
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For coronavirus maybe, because it's not much of danger for you in the first place, but those risks would be thousands of times more acceptable for cancer. There are no side effects observed from mRNA CV vaccines that could be worse when compared to cancers with 1%+ mortality rate. As a reminder you won't be taking it before the cancer, you would be taking it after the fact.
This might be true if the treatment was thousands of times more effective than the best available alternative treatment. I don't know enough about this treatment to know if that's the case or not
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mRNA will eventually save the day for everyone, including for perfectly healthy individuals, but to me as a healthy 40yo person, with no known immunity issues, not overweight etc. etc. it is in my opinion still too risky to take just like that. It's an interesting take. From what we know so far, the risk from taking vaccine is much smaller than from covid infection. You might counter this with highlighting the "so fa…
Does that matter if you get covid anyway?
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It's not about what anyone cares, but about making calculated decisions.
What
On the group level you would have to consider the damage on the group level as well from not getting vaccinated due to increase of covid-19 spread, and increased hospitalisation levels.
On the global communication and messaging level I agree you should tell everyone to vaccinate as you can't easily provide everyone with those calculators. And not to mention people not being able to come up with correct values for those factors themselves.
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Yes this should really be called a vaccine. A vaccine is a preparation that stimulates the body's immune response against diseases. For example, a specific vaccine injection (such as a flu shot) can boost the body's own immune system to help protect against a specific disease (such as the year's flu variant).
All previous vaccines were aimed at preventing infectious diseases. None of them are (primarily) indicated for preventing recurrence of a non-infectious disease. Whether it meets the technical definition or not, we can probably agree this is fundamentally different to all other vaccines. Also, since no other vaccines are custom to each patient, using the term “vaccine” could cause confusion. Do we really want to give…
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> the ones for the CV vaccine were listed on many pages of tiny text (both from Pfizer and from Moderna) The size of the pages side effects were written on says absolutely nothing about what the side effects are or their severity. > Then there are the long term consequences, many studies keep coming out with surprises (recent buzzword “Ribosomal frameshift” Ribosomal frameshift is in itself not a “long term consequen…
> The size of the pages side effects were written on says absolutely nothing about what the side effects are or their severity. Naive question: Do they say what the side effects are and their severity in an easily accessible manner somewhere?
5 WARNINGS AND PRECAUTIONS
5.1 Management of Acute Allergic Reactions
Appropriate medical treatment to manage immediate allergic reactions must be immediately available in the event an acute anaphylactic reaction occurs following administration of Moderna COVID-19 Vaccine.
Monitor Moderna COVID-19 Vaccine recipients for the occurrence of immediate adverse reactions according to the Centers for Disease Control and Prevention (CDC) guidelines (https://www.cdc.gov/vaccines/covid-19/clinical-consideration...).
5.2 Myocarditis and Pericarditis
Postmarketing data with authorized or approved mRNA COVID-19 vaccines demonstrate increased risks of myocarditis and pericarditis, particularly within the first week following vaccination. For Moderna COVID-19 Vaccine, the observed risk is highest in males 18 years through 24 years of age. Although some cases required intensive care support, available data from short-term follow-up suggest that most individuals have had resolution of symptoms with conservative management. Information is not yet available about potential long-term sequelae.
The CDC has published considerations related to myocarditis and pericarditis after vaccination, including for vaccination of individuals with a history of myocarditis or pericarditis (https://www.cdc.gov/vaccines/covid-19/clinical-consideration...).
5.3 Syncope
Syncope (fainting) may occur in association with administration of injectable vaccines. Procedures should be in place to avoid injury from fainting.
5.4 Altered Immunocompetence
Immunocompromised persons, including individuals receiving immunosuppressive therapy, may have a diminished response to Moderna COVID-19 Vaccine.
5.5 Limitations of Vaccine Effectiveness
Moderna COVID-19 Vaccine may not protect all vaccine recipients.
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We have seen how that went during covid, so dont i wouldn't hold your breath on it. The only hope is competition from China and others initiating a race to the bottom.
I mean, it seemed like it worked pretty well with covid. Vaccine was produced very quickly, and in most countries was free.