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Moderna's mRNA cancer vaccine works better than thought

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Re: Moderna's mRNA cancer vaccine works better than thought

#2
If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.

Re: Moderna's mRNA cancer vaccine works better than thought

#3
Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

Re: Moderna's mRNA cancer vaccine works better than thought

#4

Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

What kind of side effects?

Re: Moderna's mRNA cancer vaccine works better than thought

#5

Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

The side effects of most cancer treatments are aweful. How do they compare?

Re: Moderna's mRNA cancer vaccine works better than thought

#6

If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.

i love this idea. worldbank or imf or gates or thiel foundation compensates the company for opening the patent for the benefit of humanity.

Re: Moderna's mRNA cancer vaccine works better than thought

#7

If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.

I imagine an individually customized vaccine would still be expensive even if produced at-cost. Things get cheap when they can be mass produced.

Re: Moderna's mRNA cancer vaccine works better than thought

#8

If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.

We have seen how that went during covid, so dont i wouldn't hold your breath on it. The only hope is competition from China and others initiating a race to the bottom.

Re: Moderna's mRNA cancer vaccine works better than thought

#9

Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

> failed clinical trials in the 2000s and 2010s

We didn’t start testing neoantigen mRNA cancer vaccines until 2017 [1].

[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8942458/

Re: Moderna's mRNA cancer vaccine works better than thought

#10

Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

What kind of side effects?

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