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Moderna's mRNA cancer vaccine works better than thought

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Re: Moderna's mRNA cancer vaccine works better than thought

#21

If this turns out to work as promised, in a idealistic universe, Moderna gets a big influx of money from all countries in the world and they immediately publish details and surrender any patent allowing the treatment to be produced worldwide and be affordable for everyone.

i love this idea. worldbank or imf or gates or thiel foundation compensates the company for opening the patent for the benefit of humanity.

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Re: Moderna's mRNA cancer vaccine works better than thought

#22
post #5

Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

The side effects of most cancer treatments are aweful. How do they compare?

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Re: Moderna's mRNA cancer vaccine works better than thought

#23

Earlier quoted context omitted.

What kind of side effects?

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For coronavirus maybe, because it's not much of danger for you in the first place, but those risks would be thousands of times more acceptable for cancer.

There are no side effects observed from mRNA CV vaccines that could be worse when compared to cancers with 1%+ mortality rate.

As a reminder you won't be taking it before the cancer, you would be taking it after the fact.

Re: Moderna's mRNA cancer vaccine works better than thought

#24

Past mRNA cancer vaccines haven't failed to get through trials because of ineffectiveness. They failed clinical trials in the 2000s and 2010s due to their side effects being too bad. The side effects of mRNA vaccines are getting less and less severe over the years, but the proof of the pudding will come in phase III for this vaccine, as with all the other ones.

Do you have any references?

Re: Moderna's mRNA cancer vaccine works better than thought

#25
post #22
post #5

Earlier quoted context omitted.

The side effects of most cancer treatments are aweful. How do they compare?

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> bar for side effects is much stricter for preventative treatments like vaccines

These vaccines are for treatment. They don’t prevent cancer. They treat it. They’re vaccines because they work by arming your immune system versus doing the fighting themselves.

Re: Moderna's mRNA cancer vaccine works better than thought

#26
post #22
post #5

Earlier quoted context omitted.

The side effects of most cancer treatments are aweful. How do they compare?

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This does not appear to be a preventative treatment. It treats existing melanoma by inducing the body to produce antibodies against it, no?

Re: Moderna's mRNA cancer vaccine works better than thought

#27
post #13

Earlier quoted context omitted.

We have seen how that went during covid, so dont i wouldn't hold your breath on it. The only hope is competition from China and others initiating a race to the bottom.

I mean, it seemed like it worked pretty well with covid. Vaccine was produced very quickly, and in most countries was free.

Not free enough for anticapitalists!

Re: Moderna's mRNA cancer vaccine works better than thought

#28

Earlier quoted context omitted.

What kind of side effects?

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mRNA will eventually save the day for everyone, including for perfectly healthy individuals, but to me as a healthy 40yo person, with no known immunity issues, not overweight etc. etc. it is in my opinion still too risky to take just like that.

It's an interesting take. From what we know so far, the risk from taking vaccine is much smaller than from covid infection. You might counter this with highlighting the "so far" part, but keep in mind that many studies keep coming out with surprises not only regarding vaccine side effects, but also negative long term effects of covid.

Re: Moderna's mRNA cancer vaccine works better than thought

#29
post #22

Earlier quoted context omitted.

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> bar for side effects is much stricter for preventative treatments like vaccines These vaccines are for treatment. They don’t prevent cancer. They treat it. They’re vaccines because they work by arming your immune system versus doing the fighting themselves.

> The cancer vaccine: Moderna and pharma giant Merck are developing an mRNA-based cancer vaccine, mRNA-4157 (V940), for people who’ve had high-risk melanomas removed.

Re: Moderna's mRNA cancer vaccine works better than thought

#30
post #22

Earlier quoted context omitted.

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This does not appear to be a preventative treatment. It treats existing melanoma by inducing the body to produce antibodies against it, no?

It is intended for people who’ve had high-risk melanomas removed, to prevent cancer from coming back.
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