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The Uselessness of Phenylephrine (2022)

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221–230 of 350 posts

Re: The Uselessness of Phenylephrine (2022)

#221
post #207

Earlier quoted context omitted.

Dude, that report was written AFTER the laws which required it to be moved behind the counter, people to take IDs, etc. 2 years after. Smurfing was the response to that. They used those databases to identify it and target folks. That's the whole point.

I re-read it again. It says that exactly nowhere. In fact, the one specific case it did talk about, the causality was reversed: the investigation started with a couple that was recruiting other people to buy.

The law causing all these effects was passed in 2005.

https://www.deadiversion.usdoj.gov/meth/index.html

https://obamawhitehouse.archives.gov/sites/default/files/pag...

Page 5.

I’ve read press releases where the DEA flat out says they looked at the logs to identify suspicious purchasers, but i can’t find them in the noise.

Re: The Uselessness of Phenylephrine (2022)

#222
post #214

Earlier quoted context omitted.

They mention one box every six months, which is entirely reasonable.

Not sure how widespread it is or if there's a federal limit, but my state (Washington) even makes it illegal to possess more than 15 grams of it.

If my math is correct, 15 grams would mean more than 20 normal boxes of Sudafed, if each box is 24x 30mg.

I usually buy boxes of 48x 30mg, but even then I'd have to stash 10 boxes for it to be illegal.

Re: The Uselessness of Phenylephrine (2022)

#223

Probably will get downvoted for this, but a bunch of my family members are pharmacists. Their quiet opinion is that most pharmaceuticals don’t work. Even the ones that are thought effective. The data is anecdotal, but is over 15 years of watching people come in for prescriptions. The other aspect, is they say it’s mind boggling to see what kind of drugs people are on.

Of course you are going to get downvoted and you should. I know my blood pressure medicine works for instance because every time I talk to my doctor about reducing it or getting off it, I monitor my blood pressure and it spikes. I know psuedophredrine works. And your data is just that, “anecdotal”, it’s no better than the people doing “research” by watching YouTube on the toilet.

GP didn't say your blood pressure meds or pseudoephedrine don't work, they said "most drugs don't work." I would have preferred some specifics, but we didn't get them so you shouldn't argue as though they were given.

Re: The Uselessness of Phenylephrine (2022)

#224
post #210
post #108

Earlier quoted context omitted.

The effectiveness of dextrometorphan is... underwhelming in most people. But you are correct that no effective cough suppressant is available OTC in Europe.

Dextromethorphan is one of the other “scientifically proven ineffective” OTC products mentioned by the authors. Once when I had a quite severe cough I did some (highly motivated) research and my conclusion was that there is no such thing as an effective cough suppressant. At least, none that isn’t also a consciousness suppressant.

Low dose codeine is notoriously efficient.

Re: The Uselessness of Phenylephrine (2022)

#225
post #160
post #136

Earlier quoted context omitted.

You can still get pseudoephedrine, for example Claritin D, the D for decongestant. It's not by prescription but you have to sign for it at the pharmacy desk, present ID, and I believe it's reported to FDA/DEA and there are limits to how much you can buy per month.

That's mostly right, but it's not reported to anyone. It came from the "The Combat Methamphetamine Epidemic Act of 2005" . If you want to sell pseudoephedrine, your org has to "self certify", keep a logbook purchasers have to sign, require ID, enforce the purchase limits, train employees, etc. But, the logbook doesn't go anywhere unless some investigation or audit prompts that. So, if you're a really determined cooke…

>but it's not reported to anyone

I'm apparently wrong about that. Seems NPLEX/MethCheck was made a requirement US state by US state over a number of years. So there's no national monitoring, but many (most?) US states require it and give law enforcement access. And like most things set up that way, enforcement and monitoring varies by state/county/etc.

Re: The Uselessness of Phenylephrine (2022)

#226
post #81

Earlier quoted context omitted.

Ehh. Your experience is similarly anecdotal. You ignore that there is a placebo effect, blood pressure is a surrogate marker for cardiac events, and drugs can have adverse effects. It’s best to look at all cause mortality in your example. Many studies have looked at that endpoint if you are curious.

It’s “anecdotal” that I can measure with a machine that gives a number and that I track over a period time? It’s not like I said “I feel better” when taking it. So my blood pressure just magically comes down after I’m taking it?

I mean it is technically anecdotal evidence; it is just a story about you and wasn’t collected in any systemic way, we have no way to abstract it.

But there’s also lots of clinically collected evidence behind blood pressure medicine, right? I don’t see why anyone would have reason to doubt you.

Re: The Uselessness of Phenylephrine (2022)

#227

Phenylephrine did its job of convincing people to accept restricting access to pseudoephedrine, since there was a substitute that could still be freely available. Now it'll be taken off the market, but pseudoephedrine that actually works will still be restricted. At least the homeopathics consumers will buy instead have fewer side effects

I, like many others I suspect, bought phenylephrine when Sudafed first disappeared from store shelves. It was 100% ineffective for me from the first dose. In the meantime, Sudafed has become one of the most difficult to acquire substances for my daily life (I need it every day as directed by my doc). So many times when I go to a pharmacy to get it, they're out of 96-count or 48-count or any count, meaning my one allo…

I've been in this boat too, and it's infuriating. I once had a doctor that wrote me a script for it though and the pharmacy let me get a whole 90 day supply with no problems. I ended up moving and couldn't see this doc anymore, sadly. This was in the late 00s though, I don't doubt that they closed this "loophole" and don't allow docs to write for that anymore.

Re: The Uselessness of Phenylephrine (2022)

#228
post #212

Earlier quoted context omitted.

By literally going to the aisle with the decongestants, taking a pack, and paying for it like every other thing I would be buying. Like every other OTC drug. Without having to give ID, find a pharmacist, etc. I remember those days. They're long gone, obviously.

"Find a pharmacist"? I can tell you where the pharmacist is! They have their own checkout aisle!

And bankers hours, and their own waiting line! Perfect!

Re: The Uselessness of Phenylephrine (2022)

#229

Probably will get downvoted for this, but a bunch of my family members are pharmacists. Their quiet opinion is that most pharmaceuticals don’t work. Even the ones that are thought effective. The data is anecdotal, but is over 15 years of watching people come in for prescriptions. The other aspect, is they say it’s mind boggling to see what kind of drugs people are on.

It seems like a wild breach of professional ethics to sell medical treatments that they don’t believe will help their patients. Did they mistake themselves for cashiers or something?

Re: The Uselessness of Phenylephrine (2022)

#230

Earlier quoted context omitted.

And now we've got a fentanyl epidemic filling the void and even more power handed to Mexican cartels since meth got harder to produce domestically. Drugs continue to win the war on drugs.

You can't fight a war against inanimate objects. You can fight a war against drug addicts. You cannot possibly win a war against drug addicts without addressing the fundamental problem.

The problem with decriminalization/legalization is that those are the most abused drugs.

However, our drug war is causing Mexico to descend in to anarchy and people are dying by the thousands, or living in total fear of cartels that we trained in the School of the Americas.

Thus, I conclude we have to decriminalize and treat our addicts. Enforcement is not working. If we had a sane drug policy 30-40 years ago, Mexico might be a healthy vibrant trading partner.

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