The Uselessness of Phenylephrine (2022)

Post by onco » Wed, Sep 13, 2023, 6:43 PM UTC

scarface_74 wrote: post #24

greatpostman wrote: post #5

Probably will get downvoted for this, but a bunch of my family members are pharmacists. Their quiet opinion is that most pharmaceuticals don’t work. Even the ones that are thought effective. The data is anecdotal, but is over 15 years of watching people come in for prescriptions. The other aspect, is they say it’s mind boggling to see what kind of drugs people are on.

Of course you are going to get downvoted and you should. I know my blood pressure medicine works for instance because every time I talk to my doctor about reducing it or getting off it, I monitor my blood pressure and it spikes. I know psuedophredrine works. And your data is just that, “anecdotal”, it’s no better than the people doing “research” by watching YouTube on the toilet.

Post by nonethewiser » Wed, Sep 13, 2023, 6:46 PM UTC

jawns wrote: post #33

I laughed out loud when I read about the lobbyists who are trying to keep phenylephrine from being taken off store shelves. In one article about the FDA panel vote, a lobbyist said that most consumers hate the alternatives -- nasal sprays because of the discomfort and pseudoephedrine because it's stored behind the pharmacy counter -- and so depriving them of a hassle-free option is anti-consumer. The fact that the ha…

Post by kstrauser » Wed, Sep 13, 2023, 6:47 PM UTC

tptacek wrote: post #62

buildsjets wrote: post #45

Earlier quoted context omitted.

At least if I followed that path, I would not be required to have my purchase recorded in an insecure government database.

Why are you worried about the government recording your usage of Sudafed? What is anybody going to do with that information? Serious question! I understand the principle involved; I just want to know if there's some practical concern.

Post by kstrauser » Wed, Sep 13, 2023, 6:49 PM UTC

pixl97 wrote: post #70

ctoth wrote: post #55

Earlier quoted context omitted.

Unfortunately, this is the actual logic which will be used to justify it staying on shelves. > The decongestant is in at least 250 products that were worth nearly $1.8 billion in sales last year, according to an agency presentation. Look those yachts aren't gonna buy themselves.

"Ok fine, you can still sell it over the counter... except a X by Y sign stating 'This product is completely ineffective if taken in pill form' needs displayed on the shelf where the product is sold"

Post by scarface_74 » Wed, Sep 13, 2023, 6:53 PM UTC

onco wrote: post #81

scarface_74 wrote: post #24

Earlier quoted context omitted.

Of course you are going to get downvoted and you should. I know my blood pressure medicine works for instance because every time I talk to my doctor about reducing it or getting off it, I monitor my blood pressure and it spikes. I know psuedophredrine works. And your data is just that, “anecdotal”, it’s no better than the people doing “research” by watching YouTube on the toilet.

Ehh. Your experience is similarly anecdotal. You ignore that there is a placebo effect, blood pressure is a surrogate marker for cardiac events, and drugs can have adverse effects. It’s best to look at all cause mortality in your example. Many studies have looked at that endpoint if you are curious.