My kids seem to derive benefit from chewable tablets which I tell them to suck on. Curious if anyone has found different research on metabolization in the mouth versus gut?
The Uselessness of Phenylephrine (2022)
111–120 of 350 posts
Re: The Uselessness of Phenylephrine (2022)
#112Re: The Uselessness of Phenylephrine (2022)
#113Earlier quoted context omitted.
Indeed. I've known that phenylepherine is worthless for a long while, and just make it a point to buy a pack of the real stuff every 6 months or so, so that I always have it on hand when I need it. In my state, it's controlled - you have to get it from a pharmacist (though you can do so without a prescription) - they take your driver's license and don't allow you to purchase it too often.
You can buy 6 boxes of sudafed per month (24 doses each). Isn’t that more than the recommended (and probably safe) daily limit? I dont doubt your intentions but I don’t think you actually need 6 boxes per month + a stash.
Re: The Uselessness of Phenylephrine (2022)
#114Earlier quoted context omitted.
What they're going to do with it is prevent me from making a purchase if I've crossed some arbitrary limit as if exceeding that limit automatically makes me a drug trafficker. From there, it's not too far of a stretch to imagine the government assigning someone to review the list and to expend additional investigative resources into merely "suspicious" cases. Plenty of good tragedies start this way. If the government…
They're just going to say "no", right? They're not going to "automatically make you a drug trafficker". They're just trying to enforce a rate limit.
Otherwise, what right is it of the government to enact this rate limit? What interest are they protecting? How is the rate limit decided? What can I do if I disagree with the rate limit? Why is a private business being burdened with the governments agenda here?
I get where you're coming from, it _is_ a /small/ thing, but the implications immediately become onerous if you think about their meaning inside of a "free" country.
Re: The Uselessness of Phenylephrine (2022)
#115Public service announcement: sinus rinse (e.g. NeilMed) works. Available in every drug store with no prescription or pharmacist involvement necessary. It's gross, though. Do it in private.
Netty pot with salty water and a pinch of baking soda, and an even saltier water gargle clears things up nicely. And is very budget friendly.
Re: The Uselessness of Phenylephrine (2022)
#116Re: The Uselessness of Phenylephrine (2022)
#117I laughed out loud when I read about the lobbyists who are trying to keep phenylephrine from being taken off store shelves. In one article about the FDA panel vote, a lobbyist said that most consumers hate the alternatives -- nasal sprays because of the discomfort and pseudoephedrine because it's stored behind the pharmacy counter -- and so depriving them of a hassle-free option is anti-consumer. The fact that the ha…
My understanding is the nasal spray version works, but the oral just gets metabolized ineffectively?
Re: The Uselessness of Phenylephrine (2022)
#118The fact that phenylepherine is ineffective is quite old and has been common knowledge for many years. What is news is that the FDA is finally acknowledging it. I've maintained my own reserve of pseudoephedrine for years. https://gizmodo.com/report-many-over-the-counter-decongestan... https://www.forbes.com/sites/daviddisalvo/2015/10/26/the-pop... https://www.newscientist.com/article/2089555-breaking-bad-sn...
I just came here to say that I actually find phenylephrine nasal spray quite effective - but I use it for a different use case: stopping nosebleeds quickly. It's quite effective at that and came recommended by an ENT, so I do believe it's an effective vasoconstrictor when applied locally and I'm glad it's available.
Re: The Uselessness of Phenylephrine (2022)
#119Earlier quoted context omitted.
Indeed. I've known that phenylepherine is worthless for a long while, and just make it a point to buy a pack of the real stuff every 6 months or so, so that I always have it on hand when I need it. In my state, it's controlled - you have to get it from a pharmacist (though you can do so without a prescription) - they take your driver's license and don't allow you to purchase it too often.
You can buy 6 boxes of sudafed per month (24 doses each). Isn’t that more than the recommended (and probably safe) daily limit? I dont doubt your intentions but I don’t think you actually need 6 boxes per month + a stash.
Re: The Uselessness of Phenylephrine (2022)
#120Earlier quoted context omitted.
Anything a government uses to uniquely identify and track individuals (i.e. driver's license) is the target.
Until very recently, drivers license numbers were effectively public in a lot of states (they're deterministically generated from public information).