261–270 of 314 posts
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Aspirin is famous for having teratogenic effects on rabbits and would never have been approved for humans if it were to be tested nowadays
Why? Plenty of teratogenic drugs are approved and in routine use in non-pregnant patients.
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No. There was a drug released that targeted that pathway, but the approval in and of itself was a scandal - I spoke with a pharmacist last night who said people at her hospital were disgusted by the FDA’s decision. It was removed from the market two weeks later. There was basically no evidence of efficacy.
FDA approves stuff all the time that has no efficacy
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Why? Plenty of teratogenic drugs are approved and in routine use in non-pregnant patients.
Any recent example?
There are many commonly used drugs with teratogenic risks that we discontinue in pregnancy or counsel the patient on, picking randomly from a list of medications that were approved in 2023: sparsentan
I'm not sure if I'm missing something but why are you thinking teratogenicity matters when the vast majority of patients are not pregnant at a given moment?
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Ehh. We’ve been here long enough to both know that there’s a balance. $10 says the mods won’t change the title to the suggested one, precisely because of this balance. It’s not about clickbaiting. The whole reason the research is getting funded in the first place is to try to find the link.
We really need "saved you a click" version of hacker news. Same UI just title recommended by users
It's not perfect, sometimes the generated title is still totally clickbait and I've seen a couple instances of it being completely wrong or hallucinating a detail. But generally it's pretty neat.
The app also uses the same tech to summarize articles into a few bullets which I don't use as often but is also neat.
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Ohhh, I misinterpreted your comment. I think other people did too. It seemed as if you were saying that your dentist told you not to step foot in the dentist office at all for 18 months. But you just meant, the literal dentist doesn’t need to see you. Got it. I feel like this isn’t out of the ordinary now. I always hear every 6 months for a cleaning. This new “3-month” information takes a bit away from your original…
You're replying to a different person, now =]
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> A title is not "the most informative and complete sentence summarizing the article", it also has the goal to stimulate curiosity. Are you advocating clickbait?
Why did you italicize a word? Why speak with any emotion ever? Why not focus exclusively on the optimal method of transferring information from one being to another?
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Brief summarization that seems redundant to the topic because it's the model priming itself to generate a response in the requested form, which is usually a: 3-10 item list which mentions certain phrases related to the prompt every time ("nitric oxide" here). Disclaimer about accuracy/expertise.
So actually, it's a well formed answer?
Problem is all the other sets it belongs to, including the set of all answers containing unverified factual statements, not to mention the set of answers that resemble the output of a large language model.
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If you take a lot of vitamin d, make sure you also take vitamin k. Just a random source here because I'm too lazy: https://www.balancedwellbeinghealthcare.com/are-you-taking-v... > Because vitamin D is so good at improving calcium levels, by taking it alone you could be working to increase the calcification of your arteries instead of strengthening your bones so make sure to include K2 in your vitamin D supplement re…
Make sure it's vitamin K2 and not K1. Vitamin K2 is what essentially takes calcium out of your blood and puts it in your bones (and teeth). It's something that's rather lacking in western diets and could be a big reason why people in western countries suffer so many bones injuries in old age (and why our teeth suck).
That's an important distinction. Alzheimer's disease is a specific problem, separate from long-term cognitive decline. That the mechanisms of both have been identified is real progress. One way medicine progresses is by differentiating causes of the same symptoms. Then specific treatments can be worked on.
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Please note that overtaking vitamin D is unhealthy as well. It’s a hormone and I believe taking too much is damaging to the liver. But supplemental and when having a lack of Sun is probably a good balance. But if you can be in the sun your skin can make vitamin D.
Note that windows typically block the majority of the radiation that allows you to make vitamin D, so even if the sun hits you every day through your window, it's still not a good substitute for a sunny walk every once in a while. My doctor told me to go out at noon every day, but anything is better than nothing.
There is a corrugated plastic sheet (2mx1m) which allows UV-B through, but it needs replacing every few years as it breaks down and its expensive!