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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

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Re: Ozempic drug supresses desire to smoke, drink and more?

#411

Post by MagicMoonlight »

thegreenswede wrote: post #379
MagicMoonlight wrote: post #365

I was always of the opinion that being fat was a moral failing. Trying the drug really changed that. Normies have it so easy. They take one bite and feel full. My brain would scream at me continuously to try and make me eat and would never be satisfied.

"they take one bite and feel full"- I strongly disagree with this as the reason some people are just lean. As someone who's bounced around weight a lot and also had long periods where I had to basically control it (wrestling in college), the main difference I've seen with people who are in shape and people are overeat is that the former group understands that it's 'ok' to not feel full all the time. As in like learni…

Oh buddy... you're not normal. If you're yoyoing 50 pounds then you also have the eating disorder.

Trust me on this. I also thought it was a self-control thing. It's not at all. When you're normal you actually get full. I don't mean telling yourself you are full, actually full. You do not want to eat anymore. You don't want chocolate straight after eating dinner. You don't go to the fridge randomly to get snacks. You actually have no desire for food. You voluntarily stop eating during meals because you don't want to eat anymore.

It's something you can't really comprehend without experiencing it because you've experienced a lifetime of the hunger constantly telling you to eat. The idea that you could just... not want to eat is just absurd. But that's how it feels. When a normal person eats a small meal and says they are full, they are actually full. There's no self-control for them, no screaming voice or impulses.

Re: Ozempic drug supresses desire to smoke, drink and more?

#412

Post by MagicMoonlight »

sourcecodeplz wrote: post #373
MagicMoonlight wrote: post #365

I was always of the opinion that being fat was a moral failing. Trying the drug really changed that. Normies have it so easy. They take one bite and feel full. My brain would scream at me continuously to try and make me eat and would never be satisfied.

It's the same for me. I resorted to just eating yogurt, vegetables and fruits in between meals. Give it a try.

I'd rather take the medication that stops the addiction. You can't eat your way out of an eating disorder

Re: Ozempic drug supresses desire to smoke, drink and more?

#413

Post by thegreenswede »

MagicMoonlight wrote: post #411
thegreenswede wrote: post #379

Earlier quoted context omitted.

"they take one bite and feel full"- I strongly disagree with this as the reason some people are just lean. As someone who's bounced around weight a lot and also had long periods where I had to basically control it (wrestling in college), the main difference I've seen with people who are in shape and people are overeat is that the former group understands that it's 'ok' to not feel full all the time. As in like learni…

Oh buddy... you're not normal. If you're yoyoing 50 pounds then you also have the eating disorder. Trust me on this. I also thought it was a self-control thing. It's not at all. When you're normal you actually get full. I don't mean telling yourself you are full, actually full. You do not want to eat anymore. You don't want chocolate straight after eating dinner. You don't go to the fridge randomly to get snacks. You…

Miswrote: I don't yo-yo 50lb normally. Only once during the pandemic gained that much and I was purposely eating like shit bc I was angry with the lockdown situation and had nothing else to do. Just used that as an example that if I actually just eat as much as I want (like eat till I'm full-full 3x a day) with no control, I'd be 50lb heavier. But 95% of my adult life post college (9+ years), I hover around the same weight.

I guess I understand what you mean that you'd think that every skinny person must actually be full after eating and that's why they're like that, but everyone I know who is in shape (like really in shape, either ex college athlete or lives the gym life now and would be considered top 5% of the population), they absolutely do not feel full every meal/day. I mean talking about planning cheat meals and fantasizing about certain foods is super common in the fitness lifestyle.

I've met maybe 3 people in my entire life who have what you're describing: they truly don't care about food and can forget to eat meals if distracted. All the others have some form of habit/routine and wish they could eat more and stay lean.

I'm not discounting that some people really struggle with eating habits and literally cannot stop thinking to eat more (I have family members like that) but I do heavily disagree that 'normal' people are always full quickly and that's why they are 'normal' weight.

If it was a simple normal/not normal appetite wiring then why do most major cities contain way more skinny people and places like Mississippi are almost 50% obese? Or the fact that obesity was pretty rare 100 years ago. I think there's a lot more going on than just 'normal people get full quicker'.

Re: Ozempic drug supresses desire to smoke, drink and more?

#414

Post by thegreenswede »

gerbilly wrote: post #386
thegreenswede wrote: post #379

Earlier quoted context omitted.

"they take one bite and feel full"- I strongly disagree with this as the reason some people are just lean. As someone who's bounced around weight a lot and also had long periods where I had to basically control it (wrestling in college), the main difference I've seen with people who are in shape and people are overeat is that the former group understands that it's 'ok' to not feel full all the time. As in like learni…

When I'm on vacation my stress is reduced to the point where my 'appetite' drops, and this is despite the fact that I'm increasing my exercise load enormously (surfing, hiking, etc...) I've noticed that stress causes me mild stomach pain, which can register as hunger. It also causes dry mouth which registers as thirst. If you're satisfying that thirst with sugary drinks long term, then you're going to be in trouble.…

I also lose so much weight on vacation it's weird. I once lost weight when visiting Japan for two weeks but I swore I was going crazy with the food, so I was confused. But I still managed to eat less than at home (I must have). Definitely a busyness thing.

Im the opposite when it comes to stress. I lose my appetite when I'm stressed but get super super hungry when bored. The lockdowns really messed up my eating habits but thankfully I've shed all the weight now that I can actually do stuff again.

Re: Ozempic drug supresses desire to smoke, drink and more?

#415

Post by mcntsh »

hombre_fatal wrote: post #295
trasz4 wrote: post #27

Earlier quoted context omitted.

>From what I have heard, all of these issues come back as soon as someone comes off the drug Same as with drugs for hypertension, depression, hyperglycemia and many, many others. Not every drug is supposed to somehow permanently cure you.

The same could be said even for interventions like "don't eat surplus calories" and "life weights". Once you stop, you don't get the benefits and you'll regress. "But you have to do it forever" shouldn't be a convincing dismissal after 10 seconds of thought.

By completely changing your lifestyle and retuning your habits your health isn't hinging on one single point of failure (a drug you need to take).

If I stop going to the gym for a couple of months, I'm probably not going to gain any weight because I still eat healthy and stay active.

Re: Ozempic drug supresses desire to smoke, drink and more?

#416

Post by aorloff »

acjohnson55 wrote: post #29
nancyhn wrote: post #17

Earlier quoted context omitted.

Is a drug or drug-like-food (ie, sugar) dependency really the only option?

Most research indicates "yes", conditioned on the consensus of what comprises the modern lifestyle. I've been trying to understand what changed to create the obesity epidemic. Many things contribute, but it's hard to identify the smoking gun. My understanding is that one major lever seems to be the advent of snacks, refrigeration, and microwaves. Drastically reduced food prep overhead has radically alerted eating pat…

Read Gary Taubes

Re: Ozempic drug supresses desire to smoke, drink and more?

#417

Post by nwienert »

rblatz wrote: post #393
cmcaleer wrote: post #348

Earlier quoted context omitted.

I can’t find the specific study this website cites, but it mentions: > In a 2-year trial among patients with type 2 diabetes and high cardiovascular risk, patients treated with this drug experienced a great incidence of diabetic retinopathy complications (3% vs 1.8%). The absolute risk was greater in patients with a history of diabetic retinopathy at baseline (8.2%[drug] vs 5.2%[placebo]) than those without (0.7%[dru…

Non diabetic, didn’t/don’t have diabetic retinopathy. I had assumed that the detachments were unrelated to Semaglutide but just happened as a freak coincidence in time. The no apparent reason was a bit of hyperbole, since my vitreous was pulling away from the retina and brought some pieces with it during the process. But as to why that was happening at my current age is unknown. Second was likely related to stress in…

Were you prescribed it? What strength?

Re: Ozempic drug supresses desire to smoke, drink and more?

#418

Post by [deleted] »

hayst4ck wrote: post #264
trasz4 wrote: post #20

Earlier quoted context omitted.

One works, the other doesn't.

Ivermectin did feasibly improve covid outcomes, but only in places where worms were common, which is not the US. So it's true that people like the one you are responding to are ignorant and can't really understand nuance and that they are also wrong for their lack of trust in institutions, but institutions also failed to communicate to those ignorant people and that is a problem all of it's own. Very fun science read…

[deleted]

Re: Ozempic drug supresses desire to smoke, drink and more?

#419

Post by tboyd47 »

roywiggins wrote: post #15
tboyd47 wrote: post #4

[flagged]

Wegovy- semaglutide- is approved for weight loss "in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol)": https://www.fda.gov/news-events/press-announcements/fda-appr...

I appreciate the reply, really.

Re: Ozempic drug supresses desire to smoke, drink and more?

#420

Post by TeaBrain »

Jun8 wrote: post #178

So, instead is suppressing the desire to eat, how about inventing a drug that blocks the absorption or breakdown of carbohydrates in the gut? Or maybe control the gut biome so that growth of bacteria that breaks down high calorie food is minimized. Is this faster-than-light-like impossible daydream or is there any plausible path to it?

Your first proposal is what acarbose does. It is widely used in Asia, but is much less popular in Western countries. It inhibits alpha glucosidase and alpha amylase, which has the effect of decreasing the rate that complex carbohydates are broken down and absorbed.
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