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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

11–20 of 504 posts

Re: Ozempic drug supresses desire to smoke, drink and more?

#11

Now if only it didn’t cost so damn much every month even under insurance =(

Going to be huge when it goes off patent off exclusivity. I'd also expect you'll be able to get it when it's made in jurisdictions that will ignore the patent. Up to you to get it from those places, either via mail or travel runs.

They will find some way to prevent people from acquiring it and promote some other in-patent drug.

Re: Ozempic drug supresses desire to smoke, drink and more?

#12
post #11

Earlier quoted context omitted.

Going to be huge when it goes off patent off exclusivity. I'd also expect you'll be able to get it when it's made in jurisdictions that will ignore the patent. Up to you to get it from those places, either via mail or travel runs.

They will find some way to prevent people from acquiring it and promote some other in-patent drug.

Lots of ways around jurisdictional regs. Consider how many people live near a national border, or have access to the postal service.

https://www.usnews.com/news/best-states/articles/2018-11-01/...

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7523158/

https://www.cnn.com/2023/03/07/health/fda-drug-shipments-khn...

https://www.usatoday.com/story/news/health/2022/12/14/states...

Also, I expect CRISPR or gene therapy to be the long game wrt this and updating the body's GLP-1 regulation, versus maintenance doses of a pharma product. This is a shim.

https://benmay.uchicago.edu/crispr-gene-therapy

https://www.creative-biogene.com/crispr-cas9/solution/glp1r-...

Re: Ozempic drug supresses desire to smoke, drink and more?

#13

Now if only it didn’t cost so damn much every month even under insurance =(

It's not the only GLP-1 agonist out there. Victoza is another GLP-1 agonist and should be going generic in the US in a little over a year. It might already be available as a generic outside the US. There might be other GLP-1 agonists that are going generic soon as well.

Re: Ozempic drug supresses desire to smoke, drink and more?

#14
post #9

I'm surprised Ozempic gets all the press. Supposedly Mounjaro is all that and more. The wonderful Paul Ford has the best writeup I've seen that discusses these more meta levels, the post-human implications of a drug we can genuinely widescalely reprogram ourselves with. Paul's so great. https://www.wired.com/story/new-drug-switched-off-appetite-m... https://news.ycombinator.com/item?id=34660232

Ozempic has been around longer and there were a bunch of celebrities taking it and talking about it on twitter so I think it has more cultural cachet. Most people probably don't know about mounjaro, I don't even think it's approved for weight loss yet.

Re: Ozempic drug supresses desire to smoke, drink and more?

#15
post #4

[flagged]

Wegovy- semaglutide- is approved for weight loss "in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure, type 2 diabetes, or high cholesterol)":

https://www.fda.gov/news-events/press-announcements/fda-appr...

Re: Ozempic drug supresses desire to smoke, drink and more?

#16

Now if only it didn’t cost so damn much every month even under insurance =(

You can buy it as a "research chemical" and save money, but then the potential consequences of diy medicine and all that that entails are all on you. Hopefully the price will come down more as it becomes more prevalent or as generics become available.

I'm not that afraid of swallowing random chemicals but self injecting is a bit hardcore for me.

Re: Ozempic drug supresses desire to smoke, drink and more?

#17
post #5

A drug that promotes weight loss, lessens the desire to smoke, drink, etc...sounds too good to be true? From what I have heard, all of these issues come back as soon as someone comes off the drug. So either a person is committing to a lifetime of being dependent on this drug, or a person is committing to some period of time of ideal living, followed by a possible time of depression after reverting to the status quo.

For a lot of people, it's kind of a choice of which substance you are going to be dependent on. It's all expensive and sad, but between Ozempic and cigarettes, alcohol, or overeating, Ozempic has got to be healthier, and quite possibly cheaper in the long run.

Is a drug or drug-like-food (ie, sugar) dependency really the only option?

Re: Ozempic drug supresses desire to smoke, drink and more?

#18
post #11

Earlier quoted context omitted.

Going to be huge when it goes off patent off exclusivity. I'd also expect you'll be able to get it when it's made in jurisdictions that will ignore the patent. Up to you to get it from those places, either via mail or travel runs.

They will find some way to prevent people from acquiring it and promote some other in-patent drug.

It is not possible to stop people from getting mail order pills from China. Especially with the abortion restrictions the market already is pretty large and it will be easy for them to throw these drugs in too.

Re: Ozempic drug supresses desire to smoke, drink and more?

#19
post #17

Earlier quoted context omitted.

For a lot of people, it's kind of a choice of which substance you are going to be dependent on. It's all expensive and sad, but between Ozempic and cigarettes, alcohol, or overeating, Ozempic has got to be healthier, and quite possibly cheaper in the long run.

Is a drug or drug-like-food (ie, sugar) dependency really the only option?

No, there's also badmington.
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