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Ozempic drug supresses desire to smoke, drink and more?

theatlantic.com

251–260 of 504 posts

Re: Ozempic drug supresses desire to smoke, drink and more?

#251

Is this mostly a US drug? I never heard about it in France. I can't believe people love it so much without thinking about the actual source of their problem.

The source of the problem is that animals are wired to eat as much food as possible as quickly as possible. You can't blame half of the population for something that is deeply wired into our brain and bodies.

Re: Ozempic drug supresses desire to smoke, drink and more?

#253

Exercise is free and the side effects are you get stronger, more energetic, and better looking. Ozempic costs money and its side effects include cancer, kidney failure, and ruining your eyes. https://www.ozempic.com/faqs.html edit: many point out calorie intake is the real problem, it's true: buy a kitchen scale, weigh your food, count your calories, and you will lose weight. Exercise is optional compared to that. St…

Exercise does nothing for weight loss if you're eating too much. Exercise has health benefits, but weight loss is not one of them for the vast majority of people. People wildly overestimate how many calories they're burning.

Yeah, you can exercise enough for weight loss. Ultramarathoning, the Tour de France, digging canals by hand.

It only takes ten or twelve hours of high-output exercise per day. Everyone's got that time to spare, right?

Re: Ozempic drug supresses desire to smoke, drink and more?

#255

Earlier quoted context omitted.

That sounds like the lesser of two evils to me. Get healthier now and maybe sometime later lose access to the thing that helps you be healthier...or don't get healthier now? Yeah, there are other, orthogonal, choices but I don't think they're part of this particular decision matrix.

But given that the actual health benefits of ozempic(for me weight loss is not indicative of better health) have not actually been seen yet, you are quite possibly just taking on both evils at the same time.

On the contrary: GLP1 agonists show broad health benefits across the board.

Check this 24-month clinical trial with >3000 participants[0]. It showed improvements in rates of:

- Cardiovascular death

- Non-fatal Myocardial Infarction

- Non-fatal Stroke

- Revascularisation

- HbA1c

- Fasting Plasma Glucose

- Body Weight

- Lipid Profile ( total cholesterol, LDL cholesterol and triglycerides)

- Urinary Albumin to Creatinine Ratio

- Systolic blood pressure (mmHg)

- "overall health related quality of life namely bodily pain, general health, mental component summary, mental health, physical component summary, physical functioning, role-emotional, role-physical, social functioning and vitality." (each of these categories were "quantitatively" measured using a calibrated questionnaire - - and they all showed a dose-response relationship -- 1.0mg semaglutide made a bigger improvement than 0.5 mg, vs. two different placebos)

0: https://clinicaltrials.gov/ct2/show/results/NCT01720446?term...

Re: Ozempic drug supresses desire to smoke, drink and more?

#256

[flagged]

I'm a former alcoholic. I quit cold turkey years ago.

Had a drug problem before that. Cold turkey as well.

While I agree with you somewhat, I too don't like the narrative, I also realize that some people actually can't do that. Some people are faster, some smarter, some stronger, and some of us are better at sticking to a resolution. Everyone has things they're good at and things they struggle at despite the effort. Gotta find what works for you personally.

Re: Ozempic drug supresses desire to smoke, drink and more?

#257

[flagged]

Couldn’t agree more. Although I never suffered from obesity, I’ve lived a generally unhealthy lifestyle for most of my life. Slowly I’ve gotten my diet in order - not perfect, but a lot better. I haven’t had a smoke for three days, and frankly, it was easier to quit than I thought. I still get the impulse to go buy a pack, but I hold out and 20 minutes later that intrusive thought is gone.

I don’t believe a pill would do much, in the end I needed to change

Re: Ozempic drug supresses desire to smoke, drink and more?

#258
post #151

I’ve been on Mounjaro since August. Down almost 60lbs, and it’s been a life changer. Have I had some gastrointestinal issues, sure, but expected. I feel great and my brain seems to be functioning as well as when I was in my 20’s. Now, when I go to the bar with friends, I end up having maybe 2 beers and although enjoyable, I don’t feel that light switch turning on which encourages me to drink more. Can I force myself…

If you're interested - not pushing an agenda. Here's what worked for this weird dude to not drink and stay fit.

I used to lift and be real fit till about 40. Like bulky-lean looking, bench 400 10x with a 6pack. Had a lot to do with being on the road for work all over the world, and you sit at the gym at the hotel for an hour every night because of nothing else to do, and there are girls there also on business who you'll never see again. I drank A Lot, ate anything I wanted, and did lots of blo on weekends.

It was getting out of control, so I did months of google-foo, went to a pharmacy in eastern europe, got like a thousand 150mg disulfiram pills under the counter for fifty bucks, and took one pill every morning for 2 years. You don't drink, you can't drink or you die, you forget drinking exists and after a couple of months don't even think about it, yet still do all the same stuff you used to - like dancing and clubs if that's your thing. And it's even more fun. There were no side effects.

Then things changed with age, testosterone went to crap, joints hurt. I got married and settled down. Can't work out too much now - just a couple of hours per week, and no heavy weights. Within 2 years I couldn't fit into my clothes and had high blood pressure and high cholesterol.

I realized I don't eat because I'm hungry, but because it keeps away sadness. So I changed my diet so I could eat however much I want. I now have a 4-pack instead of 6, fit into my pants, and eat however much I want.

I cut out fat completely. No oil when I cook besides a light spray on the frying pan. No nuts. Tuna - not salmon. Real expensive lean filet if I want cow in my mouth. Only white meat from birds. All the pasta, rice, and potatoes I want, but zero sugar added to anything. Lots of splenda and sweet n low. Fat free fairlife milk (lactose filtered out = less sugar calories). I eat normal sized meals.

Then, I have fruit and berries, and I eat as much of that as I want. I'm stuffing my face the whole day. Today, I had a pint of blueberries, 5 medium apples, 2 mangoes, and a pound of grapes.

Speaking of gastrointestinal issues, my poo is now soft and gentle, and smells delicious.

Re: Ozempic drug supresses desire to smoke, drink and more?

#259
I am taking Contrave to lose weight. Lost 30 lbs in 4 months. It is a drug that's composed of an anti-depressant and an opioid antagonist. Together they have a synergistic effect that represses binging envy and cuts appetite.

It also has a repressive effect on drinking and smoke, to my great surprise. And it also has had an effect on my addiction to video games.

Drugs companies get a lot of slack (most of the time deserving) but sometimes they create miracles pills.

Re: Ozempic drug supresses desire to smoke, drink and more?

#260

Earlier quoted context omitted.

Reality does not need to be peer-reviewed to be true.

how could you separate actually will power from the illusion of will power?

You know the conversation has strayed once you start debating epistemology.
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