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New insights into why aspirin works so well

eurekalert.org

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Re: New insights into why aspirin works so well

#71

Post by consp »

zabzonk wrote: post #8

annecdata: aspirin is pretty good as an anti-inflamitory and hence pain-killer. the reason i don't take it is that it irritates the stomach, and i have enough issues with my insides as it is (irritable-bowel syndrome - not fun) i currently use cocodamol (codeine and paracetomol) to control my arthritic pain, but it isn't doing so great. at the end of the day, if you really need pain control, you probably want a pure…

You might be a poor codeine metaboliser. My mom and I both have this and need about twice the normally prescribed amount to have any workable effect. Always check with a medical professional before assuming you are since if it's the reverse you could easily od yourself due to rapid metabolisation of codeine to morphine.

Re: New insights into why aspirin works so well

#72

Post by DrDoonothing »

9dev wrote: post #60
11235813213455 wrote: post #47

I use nothing for reducing inflammation, nor any drugs since decades, when I'm ill from time to time (once or twice a year), I let the fever go, the body is just working actively, it's not especially uncomfortable

The body handles inflammations just fine, but you can actively help it to get it done more quickly. Doesn't have to be Aspirin though, chamomile tea and lots of other things work wonders, too.

Actually there are a lot of things which do not do anything.

Its probably one of the most fake markets out there.

Re: New insights into why aspirin works so well

#73

Post by DoreenMichele »

alkori wrote: post #58
zabzonk wrote: post #46

Earlier quoted context omitted.

> how dare the other guy suggest alternatives that do not work

So I guess all that research from respected institutions like John Hopkins is just made up? Can you show me a peer reviewed study that would prove otherwise?

I took it to mean "it doesn't work for me". If so, no peer reviewed study is required to back that up.

Re: New insights into why aspirin works so well

#74

Post by TheSpiceIsLife »

11235813213455 wrote: post #47

I use nothing for reducing inflammation, nor any drugs since decades, when I'm ill from time to time (once or twice a year), I let the fever go, the body is just working actively, it's not especially uncomfortable

I wouldn't know how old you are, some people just have such wildly good genetics they can smoke and drink till they get hit by a bus jogging at night at 98 years old.

Other people don't, you wave a celery stick near them and they put on eight pounds, a pollen particle passes within thirty kilometres of them and they're hayfever nearly kills them.

Re: New insights into why aspirin works so well

#75

Post by wiz21c »

nobody9999 wrote: post #56
simianparrot wrote: post #45

Earlier quoted context omitted.

Ibuprofen being an NSAID is high risk for anyone who’s had stomach ulcers due to its risks involved in causing GI bleeding. For people like me it’s simply not even an option.

>For people like me it’s simply not even an option. Good. More for me. ;) More seriously, you're absolutely right. Which is why even folks who can take ibuprofen should only do so within appropriate limits (IIUC, 2400mg/day maximum). I have spinal issues (disc degeneration, stenosis) which have, in the past, caused serious amounts of pain. If that pain is acute and not too serious, ibuprofen has been a life saver for…

I totally concur. Got a condition comparable to yours and ibuprofen makes a real difference whereas paracetamol just doesn't do anything. Dunno why.

Re: New insights into why aspirin works so well

#76

Post by nobody9999 »

School-Cotton wrote: post #64
nobody9999 wrote: post #41

Earlier quoted context omitted.

>It's shocking to me how we still refer to paracetamol and ibuprofen in the same breath when their relative risks are so different. And it's shocking to me how we still refer to paracetamol (Acetominophen for us USAians) and ibuprofen in the same breath, when paracetamol might as well be a sugar pill, for all the good it does and ibuprofen is the liniment of the gods!

I think this must depend on the person. Acetaminophen helps me a lot more than ibuprofen, consistently.

>I think this must depend on the person. Acetaminophen helps me a lot more than ibuprofen, consistently.

I think you're probably right.

Acetaminophen does absolutely nothing for me. Nor does Naproxen Sodium. But ibuprofen does. And consistently over decades.

I wonder if there's been any research into what makes different analgesics more or less effective for various cohorts. Unsurprisingly, there has been[0][1].

[0] https://www.npr.org/sections/health-shots/2011/09/26/1407055...

[1] The meta-study referenced in the link is from 2011.

Re: New insights into why aspirin works so well

#77

Post by imwillofficial »

seattle_spring wrote: post #57
archerx wrote: post #39

Earlier quoted context omitted.

[flagged]

You don't have any idea what you're talking about. Please stay in your lane

That’s not what this site is about. Here every lane is our lane. It’s how we grow.

Re: New insights into why aspirin works so well

#78

Post by imwillofficial »

zabzonk wrote: post #37
glass3 wrote: post #29

Earlier quoted context omitted.

If you haven't seen it: >consumer451 3 months ago | next [–] >I was diagnosed with arthritis at a very young age. [...] >One day I learned about modifying my diet to avoid inflammation. I greatly limited, but did not entirely eliminate, tomatoes and potatoes in my diet. >[...] https://news.ycombinator.com/item?id=34163231

unhappily, i was diagnosed with arthritis at quite an old age (60+) after happily eating tomatoes and tatties for all my life. i won't say what i think about advice like this.

Have you found anything that works for you?

Re: New insights into why aspirin works so well

#79

Post by zabzonk »

agentgumshoe wrote: post #69
zabzonk wrote: post #31

Earlier quoted context omitted.

believe me, i know all about pain, from experience. cannabis derived products are not going to do anything, and i have no idea what you were going on about with tumeric. the only real actual pain-killers are opioids.

Is that so? You haven't tried cannibis derived products or you would have said "did not do anything.". But ok sell the opioids.

believe me, i have used lots of cannabis products, and i am not selling anything

Re: New insights into why aspirin works so well

#80

Post by seattle_spring »

imwillofficial wrote: post #77
seattle_spring wrote: post #57

Earlier quoted context omitted.

You don't have any idea what you're talking about. Please stay in your lane

That’s not what this site is about. Here every lane is our lane. It’s how we grow.

This site is about spreading false and misleading information under the guise of "just giving helpful advice"?

Thanks but I'll continue to call out dangerous misinformation when I see it. Let's keep "reefer madness, but for pain medicine" at the fringes.

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