Earlier quoted context omitted.
From a content and branding perspective, I wouldn't touch PeerTube with a thirty-foot pole. It is fundamentally untenable unless you want people able to take screenshots of your content being featured next to literal-not-figurative Nazi shit. Yes, that's the point of federation, and that the watcher is the one who has those settings to put them next to one another. No, it's not your fault. Yes, it looks awful and it'…
You can self-host and un-federate PeerTube, such that the user isn't even aware they're on a PeerTube instance. If I had a website where I'd host my videos as an alternative to YouTube, I'd probably go with PeerTube and have people support me by seeding videos for me.
I tend to think that, since you're already foregoing discoverability by not federating with other PeerTube instances, you might as well also just build your bootleg CDN off of Hetzner nodes or whatever and have points of presence in places you care about. It's not that expensive and it's likely to be more consistent in perf. (You could say "well, run PeerTube and register your pops as peers", but other peers falling out of the swarm is the problem, not your own.)
I just don't really see a point to doing so as a small/individual creator or as a brand/channel.