131–140 of 228 posts
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Finding a doctor who's up to "non-traditional" support can be a challenge, but you've inspired me to start that search.
Besides satisfying their altruism they have nothing to gain and everything to lose if this miracle drug causes cancer in 5 years. I read up ok it. It can literally cause cancer.
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That claim is notably absent from your source.
There seems to be a growing trend of generally healthy people looking for drugs/supplements to provide marginal improvements. I can't help thinking it's a sign of a vacuous and unfulfilling life. Instead of spending time and money on drugs to increase your life span, why not spend that time/money on actually living your life? I think this probably comes down to the general boredom that comes from not having a family…
Not sure I agree with your analysis. If I had a vacuous and unfulfilling life, I wouldn't strive to prolong it.
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"Old" people are expensive because as they age, their body degrade and gets harder and harder to "maintain". If you can prevent aging, then you pay a bit upfront for prevention, but then it get cheaper later.
If you want to compare with COVID, it is cheaper to vaccinate everyone than treat the bad cases in a non-vaccinated population
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If you want to sell me on the health effects you should be able to list them. If it made you feel better but not in an objectively measurable way that's great, but that's not a health effect.
My main point was that fasting could supplement or partially replace rapamycin the drug
How does one find a doctor willing to prescribe these kinds of drugs for anti aging?
The easiest way by safely and strongly inhibit mTOR is to simply stop eating for a while. Most people don't need the drug.
if you mean fasting, say that. "stop eating for a while" to most people would be skipping lunch.
your drive by non-chalant "stop eating" / "stop eating nutrients" is just not helpful commenting the way you are
This isn't new. David Sinclair wrote about rapamycin in Lifespan[1][2] (I keep linking this book on HN a lot; no relation) [1] https://en.wikipedia.org/wiki/Lifespan_(book) [2] https://lifespanbook.com/
When somebody asks about what is the next big thing, I always think on anti-aging. If you think that you don’t want to live forever, imagine that today when you arrive home you find a note saying that you will die exactly 1531[^1] days from today. How would you feel? With that said, I would stay away from miracle drugs, because no two human beings have the same physiology. But that’s not an unsolvable problem. [^1]:…
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I wouldn't call protein breakdown in the muscle "wasting" without additional effects
> wouldn't call protein breakdown in the muscle "wasting" without additional effects Fair enough, given it's voluntary [1]. It's biologically identical to wasting, however. [1] https://en.wikipedia.org/wiki/Wasting