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Probiotics can support the effect of antidepressants

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Re: Probiotics can support the effect of antidepressants

#171

Post by appguy »

zackmorris wrote: post #138

I finally beat my digestive issues and chronic fatigue (physical depression) which lasted 3+ years from 2019-2021. Without getting too far into it, here's the stuff that finally worked, weighted by immediacy on a scale of 10: - 10: Eating a serving of Brussels sprouts, preferably daily - 10: Taking about 3 psyllium husk capsules occasionally with FODMAP and spicy meals - 10: Taking a digestive enzyme occasionally wit…

I’ve been making my own kefir and have been drinking it daily for a few months. I feel more energetic, happier and my skin looks better.

Re: Probiotics can support the effect of antidepressants

#172

Post by randycupertino »

l-albertovich wrote: post #142
pbhjpbhj wrote: post #102

Earlier quoted context omitted.

I have no medical training. This is speculation only. Consult a doctor. Assuming the translated gut flora to be the cause of your improvement then I'd look at two things. What bacteria the beneficial transplant contains, you can have it assayed (I believe it's called a bacterial culture test) and then find a cheaper source for that bacteria. Two, what the diet of the donor is, so you can try to replicate the benefici…

According to books such as "¡Es la microbiota, idiota!" (ISBN 8413440688 but I don't know if it's available in english) it's not that simple, I think they said that not all the strains are identified and even then there are strains that aren't easy to grow in vitro (I'm NOT a scientist, don't quote me on this, I just listened to the audiobook). What they make a point on is diet, she insists on the importance of havin…

> "¡Es la microbiota, idiota!"

Ha! As someone who has done clinical research on human subject on gut microbiome following blood & marrow transplants, this title is truly, truly great. My old lab needs t-shirts with that on it!

Re: Probiotics can support the effect of antidepressants

#173

Post by purplerabbit »

appguy wrote: post #171
zackmorris wrote: post #138

I finally beat my digestive issues and chronic fatigue (physical depression) which lasted 3+ years from 2019-2021. Without getting too far into it, here's the stuff that finally worked, weighted by immediacy on a scale of 10: - 10: Eating a serving of Brussels sprouts, preferably daily - 10: Taking about 3 psyllium husk capsules occasionally with FODMAP and spicy meals - 10: Taking a digestive enzyme occasionally wit…

I’ve been making my own kefir and have been drinking it daily for a few months. I feel more energetic, happier and my skin looks better.

Any advice on where to begin if interested in this?

Re: Probiotics can support the effect of antidepressants

#174

Post by markdown »

goda90 wrote: post #30
jokoon wrote: post #11

The problem is that you have to take them often to colonize your gut, so it becomes a bit expensive, and it won't work on everyone, depending on their gut (since scientists know too little about the gut).

My hypothesis is that probiotics also need to be paired with the right diet. Bacteria needs to be fed, and needs to compete with the existing gut flora. If conditions aren't right, then they may never get a foothold.

Of course the manufacturer will never tell you how to feed your pet bacteria, because they want them to die within a month so they can sell you more.

Re: Probiotics can support the effect of antidepressants

#176

Post by anotherevan »

These two episodes of the Huberman Lab podcast went into a lot of details about the gut and its effects on our mood and behaviour:

https://hubermanlab.com/how-to-enhance-your-gut-microbiome-f...

https://hubermanlab.com/dr-justin-sonnenburg-how-to-build-ma...

I found them quite interesting.

Re: Probiotics can support the effect of antidepressants

#177

Post by bwat48 »

nope96 wrote: post #131

This study scared me away from trying Probiotics: Probiotics linked to brain fog, severe abdominal bloating https://www.healio.com/news/gastroenterology/20180808/probio... “What we now know is that probiotic bacteria have the unique capacity to break down sugar and produce D-lactic acid,” he said in the press release. “So, if you inadvertently colonize your small bowel with probiotic bacteria, then you have set the s…

probiotics 'colonizing' at all is very rare, they are generally transient

Re: Probiotics can support the effect of antidepressants

#178

Post by plumeria »

bobthepanda wrote: post #168
tekno45 wrote: post #163

Earlier quoted context omitted.

Gonna be honest. I love brussel sprouts but i found a TON of dirt in my last batch and have been super apprehensive. Just wondering. How do you clean your brussel sprouts? I roast mine with olive oil and fairly simple spices.

You just rinse them in a bowl of water.

With added vinegar?

Re: Probiotics can support the effect of antidepressants

#179

Post by jollybean »

DoreenMichele wrote: post #169
jollybean wrote: post #158

Earlier quoted context omitted.

How do you know any of that worked? You can't do all that stuff to yourself - and - go through COVID (and other things) which has caused widespread depression, and assume any of that had an affect one wary or another without a fairly big randomized trial isolating all of those elements. Even just the notion of 'regime' will change people's psyches via placebo. I mean, I would certainly 'feel' healthy if I did such a…

Contrary to popular opinion, it is possible for an individual to somewhat confidently conclude that X helps them as an individual without checking it against large randomized trials. It's handwavy about some things but it doesn't assert anything beyond "I did this list of things and I, as an individual, am better now."

Sure, but 'I did these 10 things at the same time'?

... 'this is how they worked, to varying degree'?

One thing I can understand. Was sick -> did this -> was better.

But a 'regime', it feels like infomercial logic though I doubt doubt the author's motivations.

Re: Probiotics can support the effect of antidepressants

#180

Post by DoreenMichele »

jollybean wrote: post #179
DoreenMichele wrote: post #169

Earlier quoted context omitted.

Contrary to popular opinion, it is possible for an individual to somewhat confidently conclude that X helps them as an individual without checking it against large randomized trials. It's handwavy about some things but it doesn't assert anything beyond "I did this list of things and I, as an individual, am better now."

Sure, but 'I did these 10 things at the same time'? ... 'this is how they worked, to varying degree'? One thing I can understand. Was sick -> did this -> was better. But a 'regime', it feels like infomercial logic though I doubt doubt the author's motivations.

It's a single comment covering an unspecified time frame with no explanation of how much research, tracking, etc was involved. It's the TLDR of their experience in hopes of nudging people in the right direction and saying, in essence, "anecdotally, fixing my own gut issues has correlated with fewer mood issues. Here is some food for thought if you want to try to do the same."

The OP isn't selling anything, so it's not infomercial logic which is designed to get you to buy a product.

The gut is complex. I wouldn't expect one single thing to fix it.

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