Live data from Hacker News

Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

universityofcalifornia.edu

411–420 of 464 posts

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#412

Earlier quoted context omitted.

canola is probably the best out of the bunch but it's still too high in omega6s. PUFAs - as cooking oils - should be totally and utterly avoided. People should be using butter, ghee, beef tallow, coconut oil, avocado oil (which is a little higher in omega6s that i'd like but it's mostly a monosaturated fat), duck fat, emu oil. Macademia nut oil is higher in monosaturated fats than olive oil and has a higher smoke poi…

As I understand it, canola is the same as rapeseed oil, or is a refined version of it. For what I think are obvious reasons, I stay away from refined oils. However, where I live I can get locally produced cold pressed "extra virgin" rapeseed oil. How would you say that compares to canola oil regarding how healthy (or trashy) it is?

Imho it's too high in omega6s

And the omega3s it has is ALA, which your body has to convert to EPA or DHA to use, and the conversion is usually crap. Like 5-10% of ALA actually becomes something usable.

Rapeseed isbetter than canola due to the processing for canola raising the omega6 profile even higher.

But if it were up to me? I'd find another oil.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#413
post #349

Do not take this work seriously unless you are a male inbred mouse of the C57BL/6N persuasion. This is a classic N=1 study of one sex and one genome of mouse. As such this work is of almost no know relevance to other strains of mice, let alone to humanity. If you want an example of how mice dietary studies should be done then look to the National Institute on Aging and its Interventions Testing Program. They use both…

It's should be taken as a serious indication that further study is needed.

Then that should be the title of the article... If you want to be taken seriously for future studies, don't write a clickbait title off of a sample size of 1...

The article as written is making strong claims about a population it doesn't define very well...

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#414

Do not take this work seriously unless you are a male inbred mouse of the C57BL/6N persuasion. This is a classic N=1 study of one sex and one genome of mouse. As such this work is of almost no know relevance to other strains of mice, let alone to humanity. If you want an example of how mice dietary studies should be done then look to the National Institute on Aging and its Interventions Testing Program. They use both…

I think this is a fair point. I see other comments pointing out the value in this as exploratory research. There's some middle ground here though. I think studies like would serve the lay reader and non-scientific community by including a disclaimer sentence in the abstract about not extrapolating conclusions from this. Their opening sentence does the opposite, "Soybean oil consumption has increased greatly in the pa…

If you want something to be written by scientists for scientists, you have to make it inaccessible to non-scientists. Otherwise people are going to take it as the gospel truth. And honestly, they should put up major guard rails on any article interpreting a scientific study. It's too easy to miss things that other people will take to heart.

As a lay-person, when I come to this article, I have no idea of the information in the study. Which is why the veneer of a scientific study on this makes it actively worse for me to trust. And then if I ever find out the study is wrong, I trust science less, because I put my bets on a finding that was basically a coin-flip conclusion.

Now, I'm not inclined to trust the scientific process less because it finds something is wrong, but I also don't think I'm the average internet person.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#415
post #204

Earlier quoted context omitted.

Maybe that was oils in general? Eating too much cooking oil makes me feel like absolute crap mentally, regardless of type. Obviously the syndrome described in article is possible in your case, but the article sounds like a chronic accumulated damage thing, not an acute reaction just after eating.

Recently I learned the Whole Foods Plant Based diet avoids processed oils altogether, including olive and coconut. Not sure I could go that far myself, but it's interesting to know that people do it, and it's the one diet known to reverse cardiac disease.

No post body was provided.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#416
post #317

Earlier quoted context omitted.

Can’t all these things also be explained by our increasingly sedentary lifestyle?

I see three problems with that explanation. First, I'm not sure there's a strong case that our lifestyles today are any more sedentary than in, say, the 1970s (when obesity rates were around 12% rather than 30%). We had cars, transit, elevators, escalators, school buses, television, keyboards, etc. in the 1970s, while at the same time "going to the gym" was just not something that average people did on a regular basi…

There‘s a pretty marked decline in the amount of walking and cycling done in society.

In 1969 48% of US kids walked to school; in 2011 it was 13%. http://guide.saferoutesinfo.org/introduction/the_decline_of_...

Public transit is actually great for walking since you are walking to and from a stop.

People have become so unused to children walking around unsupervised that it has become grounds to call child protective services.

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#417

Earlier quoted context omitted.

Suggestions on how I can get enough complete protein in such a diet? I am open to reducing meat for health if this is a factor but eat about 150 grams complete protein every day and this is hard to replace from vegetarian. The few vegetarian dishes I see with significant protein are often not nearly as good as yogurt, meat, eggs or just stuff with whey protein in it. I can't see much with comparable protein to calori…

I'm a little confused, you write "vegetarian" but did you mean "vegan"? "The few vegetarian dishes ... are often not nearly as good as yogurt, meat, eggs, or [...] whey protein" Yogurt, eggs and whey protein are vegetarian (but not vegan). Vegetarian is extremely easy (I eat 95% vegetarian because it's cheaper and easier), vegan is very difficult and requires significant sacrifices. Or maybe I misunderstood your sent…

Hmm I don't know that I have to be either strictly, I'm thinking about cutting down my intake mostly of meat but also things like eggs that can carry through higher concentrations. Plus if there is some good complete plant protein that tastes fine, I hope maybe it's cheaper (eating lots of protein is expensive LOL)

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#419

It's nice to see the anti seed oil discourse ramping up lately, but I'm sort of pessimistic about this. Like what is the endgame, exactly? Seed oils are in basically everything. Trying to avoid them is like trying to avoid endocrine disruptors by not touching plastic or eating anything that has touched plastic. It's sort of an absurd thing to even attempt, it would drive you insane.

Basically speaking, you CANNOT eat out, no sauces, only home cooked foods. Even those need to be careful checked to not contain oils.

Technically, if you did the carnivore diet using 80% animal fat butter, or lard, then it'll be fine.

Except, the price you pay is enormous. Can't even eat a caesar salad!

Re: Soybean oil affects hypothalamus, causes genetic changes in mice: study (2020)

#420

Taking account that this is unproven in humans -- it's enough for me to avoid soybean oil, as cooking oil choice is not very important for my palate. That said, which oils would you use for frying and baking? Most high smoke point oils are, like soybean, polyunsaturated, so I'd guess that they could have some of the same (proposed) negative effects. Bonus points if the alternative is widely available (I see potential…

A few years ago, I went digging through studies and journals to answer this question. The answer I came to was avocado oil, EVOO and refined olive oil for when you desire a higher smoke point than EVOO.

EVOO, contrary to intuition, is apparently one of the better oils to use for long periods of pan and deep frying. The impurities lower the rate of oxidation of the oil and the formation of volatile organic compounds.

Post reply on HN