391–400 of 464 posts
I used to eat sardines every day trying to get the health benefits of fatty fish. They were packed in soybean oil. I drank the oil too. With time I began to have bizarre mental issues that I finally tracked down to the sardines. Sardines packed in olive oil don’t cause this issue. That’s my anecdata to share.
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Suggestions on how I can get enough complete protein in such a diet? I am open to reducing meat for health if this is a factor but eat about 150 grams complete protein every day and this is hard to replace from vegetarian. The few vegetarian dishes I see with significant protein are often not nearly as good as yogurt, meat, eggs or just stuff with whey protein in it. I can't see much with comparable protein to calori…
There's 2 ways to look at protein. There's a life-span way and a health-span way. Do you want to live longer? or do you want to feel and potentially look better? When it comes to protein, these two things seem to be at odds with one another. High protein is correlated with shorter lifespans. - https://www.nih.gov/news-events/nih-research-matters/protein... - https://www.youtube.com/watch?v=yC-ej7HbPWg You'll notice t…
The variances explained by the statistical models of longevity and health are generally woefully low.
Don’t even talk about correlation for populations unless you add the “variance explained” and unless you are sure the statical model and cofactors apply broadly.
You, as an individual, may be way out in metabolic and life-style left field. Are these recommendations even of the correct polarity for you?
We raised 80 different strains of inbred mice on both standard and very high fat (60% calories from lard) diets. Each strain was randomly assign to either diet for life with about 8 to 10 replicate “identical twins” per diet.
Do you think we can make a dietary recommendation for mouse number 81? Well at a crude level, sure. The high fat diet generally is not a good diet in terms of lifespan. But there are big deviations from the mean and at least one strain lived much longer on the ridiculous high fat diet than on the standard chow diet.
Paper by Roy S et al 2021 in Nature Metabolism, and open in bioRxiv:
Do not take this work seriously unless you are a male inbred mouse of the C57BL/6N persuasion. This is a classic N=1 study of one sex and one genome of mouse. As such this work is of almost no know relevance to other strains of mice, let alone to humanity. If you want an example of how mice dietary studies should be done then look to the National Institute on Aging and its Interventions Testing Program. They use both…
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I was at Target in the sauce aisle and I couldn't believe how literally every sauce I picked up had Soybean oil as the first ingredient.
What is surprising about that? They use what's cheapest.
Do not take this work seriously unless you are a male inbred mouse of the C57BL/6N persuasion. This is a classic N=1 study of one sex and one genome of mouse. As such this work is of almost no know relevance to other strains of mice, let alone to humanity. If you want an example of how mice dietary studies should be done then look to the National Institute on Aging and its Interventions Testing Program. They use both…
Well I am a male inbred mouse. My mother/sister and I appreciate this article immensely. We're both sight-impaired and have extra short tails.
Sorry to hear about the short tail running in the family.
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https://www.news-medical.net/health/Oils-Rich-in-Linoleic-Ac... Look, if we're going to make major life changes on the basis of this one study, you've missed the opportunity for an all-chocolate diet.
^ best post of the thread!
Does it have to be dark chocolate?
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Could you elaborate on that? It doesn't surprise we that "genetic changes" is used sensationally, just would like to know what is actually happening and whether it's uncommon or something pretty normal?
In the simplest terms: Gene expression constantly changes. It's a field known as epigenetics. You have tons of genes, not all of which are constantly active. You have histones in your DNA that allow certain portions to be read while others are locked away. This changes how your genes activate.
What is soybean oil traditionally called in the US? I've never actually seen "soybean oil" myself (though it surely exists). Is this the same as "vegetable oil"?
I was at Target in the sauce aisle and I couldn't believe how literally every sauce I picked up had Soybean oil as the first ingredient.
Hell - most "dried fruit" aside from raisins, like blueberries, dried cranberries, and so forth, are all swimming in it. Eating those "healthy" kale chips, beet chips, coconut chips? Check how much added sugar and how much omega6 ridden oils they use
Sardines are packed in soybean oil.
If it's not soybean oils, then it's cottonseed, grapseseed, canola, corn oil, or any other number of oils that we have as larger industrial byproducts.
Do not take this work seriously unless you are a male inbred mouse of the C57BL/6N persuasion. This is a classic N=1 study of one sex and one genome of mouse. As such this work is of almost no know relevance to other strains of mice, let alone to humanity. If you want an example of how mice dietary studies should be done then look to the National Institute on Aging and its Interventions Testing Program. They use both…
I think this is a fair point. I see other comments pointing out the value in this as exploratory research. There's some middle ground here though. I think studies like would serve the lay reader and non-scientific community by including a disclaimer sentence in the abstract about not extrapolating conclusions from this. Their opening sentence does the opposite, "Soybean oil consumption has increased greatly in the pa…
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Can’t all these things also be explained by our increasingly sedentary lifestyle?
I see three problems with that explanation. First, I'm not sure there's a strong case that our lifestyles today are any more sedentary than in, say, the 1970s (when obesity rates were around 12% rather than 30%). We had cars, transit, elevators, escalators, school buses, television, keyboards, etc. in the 1970s, while at the same time "going to the gym" was just not something that average people did on a regular basi…