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Heart-disease risk soars after Covid, even with a mild case

nature.com

431–440 of 546 posts

Re: Heart-disease risk soars after Covid, even with a mild case

#431
post #168

These numbers are exceptionally high on aggregate. From the article: "out of every 1,000 people studied, there were around 4 more people in the COVID-19 group than in the control group who experienced stroke." This means that for every million people who got COVID-19, we would expect 4,000 more strokes. Using a lower-bound estimate that 50% of the population will get COVID-19 at some point, this would mean roughly 65…

You seem to be assuming the U.S. is made up exclusively of 60 year old veterans.

Re: Heart-disease risk soars after Covid, even with a mild case

#432

Earlier quoted context omitted.

Not antivaxer, had my jab recently. I just respect other people's choice. Science has been settled a bit too many times in the last two years so I can understand some degree of distrust I like how I can figure out your hobbies by omissions. Have fun riding and drinking, not at the same time though ;)

Yeah, assumptions, slight of hand remarks at least you are sticking to the stereo type. Thankfully I never have to deal with people like you in a real rnd environment. surplus people.

I know, RnD departments can be very lonely places, especially these days. Anyway, was nice to have a good banter with you, friend. See you around!

Re: Heart-disease risk soars after Covid, even with a mild case

#433
post #39

COVID and the autoimmune response to it damages the endothelial layer of your cardiovascular systems. https://www.ahajournals.org/doi/10.1161/ATVBAHA.121.316101 and https://www.nature.com/articles/s41392-021-00819-6 The big question is how quickly and completely can that layer restore itself? If damage accumulates over time and people are catching new variants every 3-4 months it is only a matter of time before morta…

Bad news is that heart muscle doesn't rebuild, like how our body muscles do. But a doctor can ensure how much of our fear is right.

But that means it's almost impossible to get heart cancer, so at least we've got that going for us

Re: Heart-disease risk soars after Covid, even with a mild case

#434
post #330

Earlier quoted context omitted.

> or do you include it as an epigenetic factor? Well, in my mind `epigenetic = biological age * food intake`, where `food intake` is 'is he eating a consistent healthy diet, given that a typical person not eating healthy will surely says that she's eating healthy'. It's (unfortunately) enough to be >30yo, having bad genes around cholesterol handling pathways and eating a standard american diet (even without significa…

My cholesterol level are OK and I am Italian, so I surely don't follow an average American diet xD My gf and I love cooking and baking and all our food is freshly, with plenty of fruit and veggies, low salt in favour of spices, low sugar and plant based alternatives for butter and such :) What's apob?

What Is the Apolipoprotein B-100 (ApoB) Test?: https://www.webmd.com/cholesterol-management/what-is-apolipo...

Re: Heart-disease risk soars after Covid, even with a mild case

#435

Earlier quoted context omitted.

Omicron is not unstoppable. See mainland China. See Taiwan.

omicron is endemic in a lot of parts of the world already. it will never dissapear. china cannot adopt quarantine measures indefinitely.

> china cannot adopt quarantine measures indefinitely.

But isn’t this exactly the level of control the government wants to maintain indefinitely?

Re: Heart-disease risk soars after Covid, even with a mild case

#436
post #315

Earlier quoted context omitted.

There certainly was some disruption in gyms as workout places, but I'd be cautious about systematic conclusions like "broken everyone's regular exercise and healthy habits" given observable factors like: * increased personal time for workouts for anyone working remotely (or forgoing employment entirely) * dramatically increased demand & prices for home exercise equipment * shifts to cooking at home March / April 2020…

Absolutely. Sales of bike exercise equipment (plus Peloton’s share price), and outdoor sports gear went parabolic in 2020 and remain at record highs. The idea that “lockdowns” inhibited exercise while in many countries exercising outdoors is laughable.

No doubt there were high sales of home exercise equipment - and running became more popular.

But there were some very cautious times during lockdown. Events like Parkrun were cancelled for months on end. Loads of races were cancelled. Gyms were closed. Indoor fitness activities like dance, yoga, pilates, and aerobics were cancelled (and their online alternatives much more sparsely attended). If the place you were doing swimming/squash/tennis/golf is closed, you're out of luck. Football, hockey and basketball aren't compatible with social distancing. Neither is boxing, judo or MMA. People who commuted by foot or bike started working from home.

Running and cycling were certainly winners, but I'm certain there were a lot of losers as well.

Re: Heart-disease risk soars after Covid, even with a mild case

#438
post #331
post #259

Earlier quoted context omitted.

Funny enough, one of the original MRNA treatments developed my Moderna was something that would temporarily activate stem cell generation around heart tissue. Sounds like in testing, the mice that got the treatment after having a heart attack were much less likely to have subsequent heart attacks. https://www.youtube.com/watch?v=T4-DMKNT7xI

I was going to ask if anyone knew how they found mice for these studies. Do they choose mice they have on hand that naturally have had heart attacks? Would those mice be involved in other studies too? But I ended up googling it and sort of wish I didn’t ask the question. https://www.theawl.com/2016/04/if-you-give-a-mouse-a-heart-a...

Hopefully one day we'll have a perfect digital twin of the human body and can test drugs like this without harming animals..

Re: Heart-disease risk soars after Covid, even with a mild case

#439

Earlier quoted context omitted.

Trusting the numbers that come out of China, yeah right. Taking a look at your post history, you seem to spend a considerable amount of time defending China, what's up with that?

First off, accusations of being a shill go against HN rules. Second, the numbers that come out of China are reliable. I actually think we have a much better picture of what's going on in China with CoVID-19 than we do in almost any country, because the case numbers are low enough that each case is publicly reported in detail. Not only is there a daily rundown of the number of new cases in each city, but details about…

re normal life china. bave you ever visited /r/china ? read the stories of people living in china and how life is 'normal' there and pls report back

Re: Heart-disease risk soars after Covid, even with a mild case

#440
post #39

COVID and the autoimmune response to it damages the endothelial layer of your cardiovascular systems. https://www.ahajournals.org/doi/10.1161/ATVBAHA.121.316101 and https://www.nature.com/articles/s41392-021-00819-6 The big question is how quickly and completely can that layer restore itself? If damage accumulates over time and people are catching new variants every 3-4 months it is only a matter of time before morta…

I saw that it's mostly severe infection that results in high levels of auto-antibodies. But the studies I saw seemed to indicate that they only focused on acute infection. I wonder what the prevalence of anti-autobodies are in mild cases and how that correlates with the main article's finding of cardiovascular risk increase even in mild cases. Specifically, if these individuals already had auto-antibodies or some other outlying issue, or if this reaction is representative of the entire group.

It could take years for some autoimmune issues to arise. It would be quite concerning if this affects nearly everyone infected, including asymptomatic or mild infections following vaccination.

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