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Heart-disease risk soars after Covid, even with a mild case

nature.com

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Re: Heart-disease risk soars after Covid, even with a mild case

#311

Post by timr »

dzink wrote: post #39

COVID and the autoimmune response to it damages the endothelial layer of your cardiovascular systems. https://www.ahajournals.org/doi/10.1161/ATVBAHA.121.316101 and https://www.nature.com/articles/s41392-021-00819-6 The big question is how quickly and completely can that layer restore itself? If damage accumulates over time and people are catching new variants every 3-4 months it is only a matter of time before morta…

Both of these articles are about severe Covid-19, and study patients who were hospitalized.

It is incorrect and irresponsible to extrapolate these two papers to the entire world.

Re: Heart-disease risk soars after Covid, even with a mild case

#312

Post by postsantum »

girvo wrote: post #209
adflux wrote: post #204

Earlier quoted context omitted.

Quoted post unavailable.

If your “opinion” is contrary to observable facts and puts others in danger, yes. Pretty straightforward actually. Those posting this nonsense ignore the facts, so ignoring them seems prudent.

>observable facts

>FDA says it needs 75 years to release Pfizer COVID-19 vaccine data to the public

Re: Heart-disease risk soars after Covid, even with a mild case

#313

Post by timr »

Al-Khwarizmi wrote: post #207
lpolovets wrote: post #88

If I'm reading Figure 5 right in the original paper*, it looks like the biggest cardiac impact is on people who were hospitalized or went to the ICU for covid, and the effect on people who were not hospitalized is present but relatively small. Am I interpreting the data correctly? * https://www.nature.com/articles/s41591-022-01689-3 h/t to @greenyoda for posting elsewhere in this thread.

Relatively small compared to the impact for severe cases, but it looks very relevant if you consider the amount of people that are getting COVID and that many governments and societies are basically throwing the towel and accepting that people should just catch it.

This isn't a representative sample of the general public. Per supplementary tables 1-2, the average age of the participant was over 60, and had multiple co-morbidities. We know that age is the #1 risk factor.

The people in the "hospitalized" cohort, in particular, were quite old and sick prior to the disease.

Re: Heart-disease risk soars after Covid, even with a mild case

#314

Post by dtech »

cedivad wrote: post #293
lucd wrote: post #138

Earlier quoted context omitted.

The vaccine antigen is only a small part of the virus. Furthermore is was modified and is inert. https://cen.acs.org/pharmaceuticals/vaccines/tiny-tweak-behi... Because of international pharmacovigilance we know that ARNm vaccine induce some myocarditis and pericarditis, at a much lower rate than the virus and less severe.

50% and lower rate (the hk children myocarditis study) isn't a "much lower rate". Factor in omnicron and the clear difference between vaccinating everyone and 10% of society getting the virus and unsolvable questions should begin to arise.

99%+ eventually getting infected is more likely. Multiple countries already have confirmed infections over 10%.

Re: Heart-disease risk soars after Covid, even with a mild case

#315

Post by napier »

wwweston wrote: post #184
laurent92 wrote: post #98

Earlier quoted context omitted.

Lockdowns have also broken everyone’s regular exercise and healthy habits. On charts we all assign this to Covid, but lockdowns were an artificial, additional decision.

There certainly was some disruption in gyms as workout places, but I'd be cautious about systematic conclusions like "broken everyone's regular exercise and healthy habits" given observable factors like: * increased personal time for workouts for anyone working remotely (or forgoing employment entirely) * dramatically increased demand & prices for home exercise equipment * shifts to cooking at home March / April 2020…

Absolutely. Sales of bike exercise equipment (plus Peloton’s share price), and outdoor sports gear went parabolic in 2020 and remain at record highs. The idea that “lockdowns” inhibited exercise while in many countries exercising outdoors is laughable.

Re: Heart-disease risk soars after Covid, even with a mild case

#316

Post by benbruscella »

dijit wrote: post #150
uptownfunk wrote: post #106

This comment will probably get flagged, but I am genuinely curious from a scientific lens. What is the distribution of post-COVID heart disease conditional on having taken the vaccine?

This is actually the best reason to have people remain unvaccinated, and to not strictly mandate vaccines. I'm pro-vax (god, why do I have to say that?) but what's seriously pissed me off about this whole COVID thing is how quickly it became political. At the beginning there was a real sense of "we're in this together" but now you can be pretty certain of someones political affiliation if they choose not to wear a ma…

“Vaccines prevent you getting the worst of the illness”, on other words, a treatment…

Re: Heart-disease risk soars after Covid, even with a mild case

#317

Post by csee »

Fomite wrote: post #292
csee wrote: post #187

Earlier quoted context omitted.

Are there any problems with that paper that would invalidate their conclusion that myocarditis is more likely in young men who get Moderna than young men who get Covid?

My biggest concern is the studies that have been comparing myocarditis induced by the vaccine vs. those with MIS-C from COVID-19 that show that they're not necessarily directly comparable - the vaccine-induced version is also milder. It is elevated, but the implications of that depend wildly on things like case rates, as events/vaccine doses is static, and events/cases is dynamic. A conclusion reached in Sept., 2021…

Do you have a source on the vaccine-induced myocarditis being milder? If that's true then it is indeed a crucial thing to keep in mind when interpreting these results.

Re: Heart-disease risk soars after Covid, even with a mild case

#318

Post by timr »

lpolovets wrote: post #88

If I'm reading Figure 5 right in the original paper*, it looks like the biggest cardiac impact is on people who were hospitalized or went to the ICU for covid, and the effect on people who were not hospitalized is present but relatively small. Am I interpreting the data correctly? * https://www.nature.com/articles/s41591-022-01689-3 h/t to @greenyoda for posting elsewhere in this thread.

Yes. Also read the supplementary tables that describe the demographic co-variates of the study population:

https://static-content.springer.com/esm/art%3A10.1038%2Fs415...

Mean age of the Covid-19 cohort: 61.42

Percent with BMI over 30: 53.84%

Percent with chronic kidney disease: 19.52%

Lung disease: 15.26%

Diabetes: 32.13%

Hyperlipidemia: 33.97%

Hypertension: 26.7%

Almost all of these factors are significantly elevated over the control groups, and their attempts to normalize the data (ST2) do not eliminate the problem. We're talking about tiny differences in small numbers, and their population is biased toward the sick and the old. It's already clear from the main paper that most of the signal comes from the oldest, sickest cohort, but once you know that pretty much everyone in the study was old and sick, it's clearly difficult to generalize from this.

This thread is awash with 20-somethings pontificating about heart damage based on a paper about elderly veterans. Simply irresponsible reporting.

Re: Heart-disease risk soars after Covid, even with a mild case

#319

Post by bjoli »

passerby1 wrote: post #227
bjoli wrote: post #164

Earlier quoted context omitted.

Both my gym and pool were closed for almost half a year in Sweden.

In Göteborg SATS nor Friskis&Svettis were never closed during the pandemic. I also knew that Fitness24 was open all the way too. Which gym are you talking about?

My gym and pool area in the same building, run by the same company (medley). The pool was closed by the city and the gym was closed by proxy.

Fitness24/7 in town was so small that it was impossible to get in due to covid retrictions. Something like a maximum of 9 people which meant that it was impossible to get in during popular hours.

Re: Heart-disease risk soars after Covid, even with a mild case

#320

Post by DwarvenAcademy »

verisimi wrote: post #191
bpizzi wrote: post #132

Earlier quoted context omitted.

That's terrible, I hope you're recovering to the best possible. Do you happen to know what was your blood pressure prior to the heart attack, and/or your apob level? At least you should have it checked now (I assume that's what have been prescribe by your doctors). It is my understanding that it is more statistically sound to point the cause of a heart attack at your age to genetic/epigenetic factors instead of a pot…

"It is my understanding that it is more statistically sound to point the cause of a heart attack at your age to genetic/epigenetic factors instead of a potential coronavirus infection with no symptoms." He's saying that he has an effect 2 months after the vaccine. Is that not also worthy of consideration, or do you include it as an epigenetic factor?

Sorry I should point out I had pains even before the first dose but every doctor or specialist I consulted thought they were muscular pains (right chest and shoulder area). So it's likely a vaccine is not the cause but there are so many factors and cofactors to consider it's very hard to make a diagnosis. Other blood tests in March will hopefully clear some of this out --
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