Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Having SARS-CoV-2 once confers much greater immunity than a vaccine

sciencemag.org

Post reply on HN
Print view View original

31–40 of 371 posts

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#31

Post by kiba »

mc32 wrote: post #13
SketchySeaBeast wrote: post #5

I can only consider this a positive for those who are vaccine hesitant, as they will probably be getting it, but I can't see how, considering the realistic dangers of a vaccine, a rational individual wouldn't want both forms of protection even if they were previously infected.

I think people in high risk groups should get it, i.e., the elderly and people with weak immune systems or other health issues. Those who are strong health wise ok, they stand a good chance. That said, I am totally against this blanket insistence on passports. There may be some situations which warrant vaccinations where the subject has no acquired immunity, health workers, etc. But being denied access to govt servic…

Wearing a mask is a mild annoyance. With vaccine, you might suffer side effects, but even that is short term.

It's basically no-brainer, since getting infected with the virus is more likely to kill you than getting the vaccine.

The only reason people are not getting the vaccine is for various reasons they don't trust that the vaccine is going to help them. Everything else is justification.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#32

Post by Tenoke »

mc32 wrote: post #13
SketchySeaBeast wrote: post #5

I can only consider this a positive for those who are vaccine hesitant, as they will probably be getting it, but I can't see how, considering the realistic dangers of a vaccine, a rational individual wouldn't want both forms of protection even if they were previously infected.

I think people in high risk groups should get it, i.e., the elderly and people with weak immune systems or other health issues. Those who are strong health wise ok, they stand a good chance. That said, I am totally against this blanket insistence on passports. There may be some situations which warrant vaccinations where the subject has no acquired immunity, health workers, etc. But being denied access to govt servic…

In Europe you can show a recent test or your Vax passport anywhere (e.g. you need one or the other to travel or go to the gym) and I really don't see the issue.

I'm glad there's a way to ensure only low risk people are in the places I go to and the privacy risks are comparable or smaller than for things with lesser benefits.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#33

Post by SV_BubbleTime »

bigmattystyles wrote: post #14

But don’t you risk long hauler symptoms or worse? Meaning, it’s an interesting datapoint but not a viable strategy.

We know as much about “long Covid, as we know about “long covid vaccine“.

That’s not pro or con anything, it’s just the truth that some are having a hard time admitting.

I’m not sure at what point in the last year “we don’t know” became taboo. Maybe when we wrapped unknowns in policy decisions?

EDIT: yes, we have data for that long Covid symptoms especially in severe cases, and suspected in mild cases, my point was that we do not have enough data to make policy decisions based on this. Currently hard to quantify, as the CDC has anxiety and depression listed as long Covid symptoms.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#34

Post by vibrato2 »

SketchySeaBeast wrote: post #5

I can only consider this a positive for those who are vaccine hesitant, as they will probably be getting it, but I can't see how, considering the realistic dangers of a vaccine, a rational individual wouldn't want both forms of protection even if they were previously infected.

Consider the realistic uncertainty and probability from previous study of antibody dependent enhancement. It’s not proven that the mRNA therapy won’t worsen covid reaction in the long run.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#35

Post by sokoloff »

vibrato2 wrote: post #30
bigmattystyles wrote: post #14

But don’t you risk long hauler symptoms or worse? Meaning, it’s an interesting datapoint but not a viable strategy.

Working very viably for myself.

Well, we should just scale your experience/anecdote up by 8 billion and we’re good then.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#36

Post by peteradio »

bigmattystyles wrote: post #14

But don’t you risk long hauler symptoms or worse? Meaning, it’s an interesting datapoint but not a viable strategy.

Its not about vaccine vs natural immunity. Its about immunity vs mandates.

Getting covid intentionally is stupid. If you feel up to it, get the vaccine. Any encounter with covid will be milder.

However, some people have already had it and are frankly being unjustly discriminated in some states and institutions.

I'm not against vaccines but the treatment of previously infected people as second tier has got to stop.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#38

Post by vibrato2 »

kiba wrote: post #31
mc32 wrote: post #13

Earlier quoted context omitted.

I think people in high risk groups should get it, i.e., the elderly and people with weak immune systems or other health issues. Those who are strong health wise ok, they stand a good chance. That said, I am totally against this blanket insistence on passports. There may be some situations which warrant vaccinations where the subject has no acquired immunity, health workers, etc. But being denied access to govt servic…

Wearing a mask is a mild annoyance. With vaccine, you might suffer side effects, but even that is short term. It's basically no-brainer, since getting infected with the virus is more likely to kill you than getting the vaccine. The only reason people are not getting the vaccine is for various reasons they don't trust that the vaccine is going to help them. Everything else is justification.

Did you miss the part of the fda statement this week where they said they have no long term data available?

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#39

Post by KaiserPro »

AndrewBissell wrote: post #3

There's really nothing surprising about this conclusion. Before Covid came along and the focus inexplicably shifted to antibodies-only, it was well understood that infection with a pathogen was always likely to result in better immunity than vaccination.

kinda.

its more complex and nuanced than this. I had thought that the chickenpox vaccine gave you a higher chance of shingles in later life. However that appears to be the opposite of what actually happens.

The crucial thing is that its dependent on the vaccine and the thing infecting you.

For example the BCG jab which protects against TB is wild. Its a live vaccine that has been evolving, got lost once, and its kinda black magic. In older people it has a ~33% efficacy. its much more effective in babies and children though.

However we've got to the point that TB is so rare in the UK that targeted vaccination is more than enough to keep it under control.

With covid, we need to make sure that when people get it, they don't get seriously ill. Ideally they wont get it at all, but alas thats not the case, the vaccines are not effective enough for that against this variant.

I assume that altering the mrna vaccines would have a similar speed as the annual flu vaccine, so changes for new variants would require less development time.

But as someone pointed out, if you have a vaccine, and you get covid, te seems reasonable to assume that you will have a better immunity.

Also with just 8 cases out 32k, it seems a small dataset to draw conclusions on.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#40

Post by ukj »

AndrewBissell wrote: post #18
blablablub wrote: post #8

Survivorship bias comes to mind https://en.wikipedia.org/wiki/Survivorship_bias

Not sure how that's really relevant when over 99% of people in both the vaccinated and unvaccinated cohorts do not die from Covid.

The entire point of vaccintation is to enable a road to immunity which kills less people than simply getting infected.

If we were OK with the death rate of naturally-attained immunity we didn't need a vaccine.

Post reply on HN